The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Regulation of ES cell differentiation by functional and conformational modulation of p53
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Citations
Cites
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., & Bradley, A. (1992) · Nature · doi:10.1038/356215a0 · Cited by 4,649
Mdm2 promotes the rapid degradation of p53
Haupt, Y., Maya, R., Kazaz, A., & Oren, M. (1997) · Nature · doi:10.1038/387296a0 · Cited by 4,506
Regulation of p53 stability by Mdm2
Kubbutat, M. H. G., Jones, S. N., & Vousden, K. H. (1997) · Nature · doi:10.1038/387299a0 · Cited by 3,312 · cited 1×
“It is possible that the recently suggested mechanism of regulation of p53 stability by mdm2 (Haupt et al., 1997; Kubbutat et al., 1997) might not be operational in this system, and hence p53 is maintained at high levels.”
BackgroundDefinition of a consensus binding site for p53
El-Deiry, W. S., Kern, S. E., Pietenpol, J. A., Kinzler, K. W., & Vogelstein, B. (1992) · Nature Genetics · doi:10.1038/ng0492-45 · Cited by 1,985
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
de Oca Luna, R. M., Wagner, D. S., & Lozano, G. (1995) · Nature · doi:10.1038/378203a0 · Cited by 1,420 · cited 3×
“Furthermore, mice lacking mdm2 die due to presence of p53 (de Oca Luna et al., 1995; Jones et al., 1995).”
BackgroundRescue of embryonic lethality in Mdm2-deficient mice by absence of p53
Jones, S. N., Roe, A. E., Donehower, L. A., & Bradley, A. (1995) · Nature · doi:10.1038/378206a0 · Cited by 1,280
Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor
Sibilia, M., & Wagner, E. F. (1995) · Science · doi:10.1126/science.7618085 · Cited by 1,002
Self-citationp53-Dependent apoptosis suppresses tumor growth and progression in vivo
Symonds, H., Krall, L., Remington, L., Saenz-Robles, M., Lowe, S., Jacks, T., & Van Dyke, T. (1994) · Cell · doi:10.1016/0092-8674(94)90534-7 · Cited by 880 · cited 1×
“Thus, in the absence of a wild-type p53 or the presence of a mutated p53 gene product, cells fail to arrest in G1 or undergo apoptosis in response to DNA damage, and mutations are propagated leading to tumorigenesis (Kemp et al., 1994; Symonds et al., 1994).”
BackgroundSpecific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53
Mack, D. H., Vartikar, J., Pipas, J. M., & Laimins, L. A. (1993) · Nature · doi:10.1038/363281a0 · Cited by 322 · cited 2×
“Although p53 has been shown to repress transcription of several genes (Ginsberg et al., 1991; Lechner et al., 1992; Mack et al., 1993; Harris et al., 1996), this may not be the mechanism regulating proliferation of differentiated cells, as transcriptional repression was observed when p53 adopted a…”
Background
Cited by
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
Jackson-Grusby, L., Beard, C., Possemato, R., Tudor, M., Fambrough, D., Csankovszki, G., Dausman, J., Lee, P., Wilson, C., Lander, E., et al. (2001) · Nature Genetics · doi:10.1038/83730 · Cited by 694
A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity
Percharde, M., Lin, C.-J., Yin, Y., Guan, J., Peixoto, G. A., Bulut-Karslioglu, A., Biechele, S., Huang, B., Shen, X., & Ramalho-Santos, M. (2018) · Cell · doi:10.1016/j.cell.2018.05.043 · Cited by 555
Reactivation of mutant p53: molecular mechanisms and therapeutic potential
Selivanova, G., & Wiman, K. G. (2007) · Oncogene · doi:10.1038/sj.onc.1210295 · Cited by 186
Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors
North, S., Moenner, M., & Bikfalvi, A. (2005) · Cancer Letters · doi:10.1016/j.canlet.2004.08.007 · Cited by 113
Mutation of Mouse p53 Ser23 and the Response to DNA Damage
Wu, Z., Earle, J., Saito, S., Anderson, C. W., Appella, E., & Xu, Y. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.8.2441-2449.2002 · Cited by 103
Metadata
- Authors
- Sabapathy, K.
- Venue
- The EMBO Journal
- Published
- 1997-10-15
- Volume
- 16
- Issue
- 20
- Pages
- 6217-6229
- ISSN
- 0261-4189 (ISSN-L)
- 1460-2075
- OpenAlex
- W2128020963
- Cited by
- 159
- References
- 9
- FWCI
- 2.72
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Regulation of ES cell differentiation by functional and conformational modulation of p53. https://app.cochat.ai/papers/10.1093/emboj/16.20.6217
- The paper
- Sabapathy, K. (1997). Regulation of ES cell differentiation by functional and conformational modulation of p53. The EMBO Journal. https://doi.org/10.1093/emboj/16.20.6217
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
