A newly identified N‐terminal amino acid sequence of human eIF4G binds poly(A)‐binding protein and functions in poly(A)‐dependent translation

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.

Fuerst, T. R., Niles, E. G., Studier, F. W., & Moss, B. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.21.8122 · Cited by 2,078 · see citing works

Circularization of mRNA by Eukaryotic Translation Initiation Factors

Wells, S. E., Hillner, P. E., Vale, R. D., & Sachs, A. B. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80122-7 · Cited by 981 · see citing works

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.

Gallie, D. R. (1991) · Genes & Development · doi:10.1101/gad.5.11.2108 · Cited by 868 · see citing works

Initiation of Protein Synthesis in Eukaryotic Cells

Pain, V. M. (1996) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1996.00747.x · Cited by 712 · see citing works

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF‐4G.

Tarun, S. Z., & Sachs, A. B. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01108.x · Cited by 690 · see citing works

The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding Proteins

Mader, S., Lee, H. B., Pause, A., & Sonenberg, N. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.9.4990 · Cited by 685 · see citing works

Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes

Sachs, A. B., Sarnow, P., & Hentze, M. W. (1997) · Cell · doi:10.1016/s0092-8674(00)80268-8 · Cited by 679 · see citing works

The mRNA 5′ cap-binding protein eIF4E and control of cell growth

Sonenberg, N., & Gingras, A. (1998) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(98)80150-6 · Cited by 673 · see citing works

Mapping of Functional Domains in Eukaryotic Protein Synthesis Initiation Factor 4G (eIF4G) with Picornaviral Proteases

Lamphear, B. J., Kirchweger, R., Skern, T., & Rhoads, R. E. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.37.21975 · Cited by 557 · see citing works

Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.

Duncan, R., Milburn, S. C., & Hershey, J. W. B. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75938-9 · Cited by 483 · see citing works

A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: Domain structure and expression

Sachs, A. B., Bond, M. W., & Kornberg, R. D. (1986) · Cell · doi:10.1016/0092-8674(86)90557-x · Cited by 388 · see citing works

A common function for mRNA 5' and 3' ends in translation initiation in yeast.Preprint

Tarun, S. Z., & Sachs, A. B. (1995) · Genes & Development · doi:10.1101/gad.9.23.2997 · Cited by 374 · see citing works

Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

Craig, A. W., Haghighat, A., Yu, A. T. K., & Sonenberg, N. (1998) · Nature · doi:10.1038/33198 · Cited by 367 · see citing works

mRNA poly(A) tail, a 3' enhancer of translational initiation.

Munroe, D. J., & Jacobson, A. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.7.3441 · Cited by 351 · see citing works

Functional Dissection of Eukaryotic Initiation Factor 4F: the 4A Subunit and the Central Domain of the 4G Subunit Are Sufficient To Mediate Internal Entry of 43S Preinitiation Complexes

Pestova, T. V., Shatsky, I. N., & Hellen, C. U. T. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.12.6870 · Cited by 348 · see citing works

Rotavirus RNA‐binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F

Piron, M., Vende, P., Cohen, J., et al. (1998) · The EMBO Journal · doi:10.1093/emboj/17.19.5811 · Cited by 334 · see citing works

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

Tarun, S. Z., Wells, S. E., Deardorff, J. A., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.9046 · Cited by 316 · see citing works

A Novel Functional Human Eukaryotic Translation Initiation Factor 4G

Gradi, A., Imataka, H., Svitkin, Y. V., Rom, E., Raught, B., Morino, S., & Sonenberg, N. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.1.334 · Cited by 296 · see citing works

Human Eukaryotic Translation Initiation Factor 4G (eIF4G) Possesses Two Separate and Independent Binding Sites for eIF4A

Imataka, H., & Sonenberg, N. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.12.6940 · Cited by 292 · see citing works

Pattern-induced multi-sequence alignment (PUMA) algorithm employing secondary structure-dependent gap penalties for use in comparative protein modelling

Smith, R. F., & Smmith, T. F. (1992) · Protein Engineering Design and Selection · doi:10.1093/protein/5.1.35 · Cited by 280 · see citing works

Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast

Preiß, T., & Hentze, M. W. (1998) · Nature · doi:10.1038/33192 · Cited by 270 · see citing works

RNA-protein interactions in regulation of picornavirus RNA translation

Belsham, G. J., & Sonenberg, N. (1996) · Microbiological Reviews · doi:10.1128/mr.60.3.499-511.1996 · Cited by 266 · see citing works

Translation Initiation Factors eIF-iso4G and eIF-4B Interact with the Poly(A)-binding Protein and Increase Its RNA Binding Activity

Le, H., Tanguay, R. L., Balasta, M. L., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.26.16247 · Cited by 262 · see citing works

The mRNA Poly(A)-Binding Protein: Localization, Abundance, and RNA-Binding Specificity

Görlach, M., Burd, C. G., & Dreyfuss, G. (1994) · Experimental Cell Research · doi:10.1006/excr.1994.1104 · Cited by 247 · see citing works

The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.

Burd, C. G., Matunis, E. L., & Dreyfuss, G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.7.3419 · Cited by 222 · see citing works

2 The Pathway and Mechanism of Eukaryotic Protein SynthesisPreprint

Merrick, W. C., & Hershey, J. W. B. (1996) · Cold Spring Harbor Monograph Archive · doi:10.1101/087969458.30.31 · Cited by 221 · see citing works

A new translational regulator with homology to eukaryotic translation initiation factor 4G

Imataka, H., Olsen, H. S., & Sonenberg, N. (1997) · The EMBO Journal · doi:10.1093/emboj/16.4.817 · Cited by 221 · see citing works

Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif

Grange, T., de, C. M., Oddos, J., et al. (1987) · Nucleic Acids Research · doi:10.1093/nar/15.12.4771 · Cited by 188 · see citing works

TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

Goyer, C., Altmann, M., Lee, H. S., Blanc, A., Deshmukh, M., Woolford, J. L., Trachsel, H., & Sonenberg, N. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.8.4860 · Cited by 183 · see citing works

RNA Recognition Motif 2 of Yeast Pab1p Is Required for Its Functional Interaction with Eukaryotic Translation Initiation Factor 4G

Kessler, S. H., & Sachs, A. B. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.1.51 · Cited by 167 · see citing works

eIF4G: translation's mystery factor begins to yield its secrets.

Morley, S., Curtis, P. S., & Pain, V. M. (1997) · PubMed · Cited by 163 · see citing works

The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase

Haghighat, A., Svitkin, Y. V., Novoa, I., Kuechler, E., Skern, T., & Sonenberg, N. (1996) · Journal of Virology · doi:10.1128/jvi.70.12.8444-8450.1996 · Cited by 155 · see citing works

Amino acid sequence of the human protein synthesis initiation factor eIF-4 gamma

Yan, R., Rychlik, W., Etchison, D., & Rhoads, R. E. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50080-6 · Cited by 140 · see citing works

mRNA Poly (A) Tail, a 3′ Enhancer of Translational Initiation

Munroe, D. J., & Jacobson, A. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.7.3441-3455.1990 · Cited by 138 · see citing works

mRNA 5' cap-binding protein eIF4E and control of cell growth

Sonenberg, N. (1996) · Medical Entomology and Zoology · Cited by 123 · see citing works

The Multiple RNA-Binding Domains of the mRNA Poly(A)-Binding Protein Have Different RNA-Binding Activities

Burd, C. G., Matunis, E. L., & Dreyfuss, G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.7.3419-3424.1991 · Cited by 99 · see citing works

Isolation and sequence of the cDNAs encoding the subunits of the isozyme form of wheat protein synthesis initiation factor 4F

Allen, M. L., Metz, A. M., Timmer, R. T., et al. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50081-8 · Cited by 88 · see citing works

The poly(A)‐binding protein facilitates in vitro translation of poly(A)‐rich mRNA

de SA, M. G., Standart, N., de, C. M., et al. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14309.x · Cited by 84 · see citing works

TIF4631 and TIF4632 : Two Yeast Genes Encoding the High-Molecular-Weight Subunits of the Cap-Binding Protein Complex (eukaryotic initiation factor 4F) Contain an RNA Recognition Motif-Like Sequence and Carry out an Essential Function

Goyer, C., Altmann, M., Lee, H. S., Blanc, A., Deshmukh, M., Woolford, J. L., Trachsel, H., & Sonenberg, N. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.8.4860-4874.1993 · Cited by 58 · see citing works

The proteolytic cleavage of eukaryotic initiation factor (eIF) 4G is prevented by eIF4E binding protein (PHAS‐I; 4E‐BP1) in the reticulocyte lysate

Ohlmann, T., Pain, V. M., Wood, W., et al. (1997) · The EMBO Journal · doi:10.1093/emboj/16.4.844 · Cited by 54 · see citing works

Isolation and characterization of the cDNA and the gene for eukaryotic translation initiation factor 4G from Drosophila melanogaster

Hernández, G., Castellano, M. M., Agudo‐Barriuso, M., et al. (1998) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1998.2530027.x · Cited by 25 · see citing works

Engineering circular RNA for potent and stable translation in eukaryotic cells

Wesselhoeft, R. A., Kowalski, P. S., & Anderson, D. G. (2018) · Nature Communications · doi:10.1038/s41467-018-05096-6 · Cited by 884 · see citing works

Signalling to translation: How signal transduction pathways control the protein synthetic machinery

Proud, C. G. (2007) · Biochemical Journal · doi:10.1042/bj20070024 · Cited by 520 · see citing works

Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms

Kahvejian, A., Svitkin, Y. V., Sukarieh, R., M'Boutchou, M.-N., & Sonenberg, N. (2005) · Genes & Development · doi:10.1101/gad.1262905 · Cited by 491 · see citing works

Therapeutics Based on Stop Codon Readthrough

Keeling, K. M., Xue, X., Gunn, G., & Bedwell, D. M. (2014) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-091212-153527 · Cited by 306 · see citing works

Transcript-Selective Translational Silencing by Gamma Interferon Is Directed by a Novel Structural Element in the Ceruloplasmin mRNA 3′ Untranslated Region

Sampath, P., Mazumder, B., Seshadri, V., & Fox, P. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.5.1509-1519.2003 · Cited by 130 · see citing works

The Poly(A)-Binding Protein and an mRNA Stability Protein Jointly Regulate an Endoribonuclease Activity

Wang, Z., & Kiledjian, M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.17.6334-6341.2000 · Cited by 113 · see citing works

Importin α-Mediated Nuclear Import of Cytoplasmic Poly(A) Binding Protein Occurs as a Direct Consequence of Cytoplasmic mRNA Depletion

Kumar, G. R., Shum, L., & Glaunsinger, B. A. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05402-11 · Cited by 71 · see citing works

An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4

Fehler, O., Singh, P., Haas, A., Ulrich, D., Müller, J. P., Ohnheiser, J., & Klempnauer, K.-H. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku800 · Cited by 35 · see citing works

Cloning and Characterization of Rat BAT3 cDNA

Ozaki, T., Hanaoka, E., Naka, M., et al. (1999) · DNA and Cell Biology · doi:10.1089/104454999315222 · Cited by 22 · see citing works

EFFECT OF THE NEMATODE PHASMARHABDITIS HERMAPHRODITA ON YOUNG STAGES OF THE PEST SLUG ARION LUSITANICUS

Grimm, B. (2002) · Journal of Molluscan Studies · doi:10.1093/mollus/68.1.25 · Cited by 41 · see citing works

HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53Preprint

Sasaki, T., Gan, E. C., Wakeham, A. C., Kornbluth, S. A., Mak, T. W., & Okada, H. (2007) · Genes & Development · doi:10.1101/gad.1534107 · Cited by 127 · see citing works

Anthoxanthum Mosaic Virus

Catherall, P. L. (1970) · Plant Pathology · doi:10.1111/j.1365-3059.1970.tb00999.x · Cited by 6 · see citing works

Ecological and evolutionary importance of neighbors in the grass Anthoxanthum odoratum

Platenkamp, G. A. J., & Foin, T. C. (1990) · Oecologia · doi:10.1007/bf00317753 · Cited by 21 · see citing works