Cited by 233Cardiac Valve Diseases and TreatmentsCardiovascular Function and Risk FactorsAortic Disease and Treatment Approaches

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Left ventricular hypertrophy in aortic valve stenosis: preventive or promotive of systolic dysfunction and heart failure?

Kupari, Markku, Turto, Heikki, Lommi, Jyri·2005·European Heart Journal

DOI 10.1093/eurheartj/ehi290

Open this paper in CoChat — free account

Abstract

AIMS: In aortic stenosis (AS), left ventricular (LV) hypertrophy is considered a compensatory response helping maintain systolic function. Recent research in experimental AS suggests, however, that LV hypertrophy is not necessary to sustain LV contractions but may in fact be maladaptive. The present work aimed to clarify the role of LV hypertrophy in AS-related heart failure (HF) in man. METHODS AND RESULTS: We studied 137 adult patients with isolated AS undergoing pre-operative echocardiography and cardiac catheterization. HF was diagnosed by the European criteria and LV hypertrophy by sex-specific limits of echocardiographic LV mass. The higher the LV mass was, the poorer was the LV ejection fraction (beta=-0.26, P< 0.001, linear regression) and the greater the likelihood of HF independent of the severity of AS (P< 0.001, logistic regression). In the subgroup of critical AS (valve area <0.4 cm(2)/m(2), n=85), patients with absent LV hypertrophy (n=19) had better preserved ejection fraction (mean+/-SE, 64+/-3 vs. 57+/-2%, P=0.045) and less HF (16 vs. 48%, P=0.025) than patients with LV hypertrophy (n=66). CONCLUSION: In isolated AS, increased LV mass predicts the presence of systolic dysfunction and HF independent of the severity of valvular obstruction. LV hypertrophy may be maladaptive rather than beneficial in AS in man.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1093/eurheartj/ehi290

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,487
Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings
Devereux, R. B., Alonso, D. R., Lutas, E. M., Gottlieb, G. J., Campo, E., Sachs, I., & Reichek, N. (1986) · The American Journal of Cardiology · doi:10.1016/0002-9149(86)90771-x · Cited by 6,226
Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart study
Levy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005313222203 · Cited by 5,699
Wall stress and patterns of hypertrophy in the human left ventricle.
Grossman, W., Jones, D., & McLaurin, L. P. (1975) · Journal of Clinical Investigation · doi:10.1172/jci108079 · Cited by 2,403
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T. M., Porenta, G., Lang, I. M., Christ, G., SCHEMPER, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,332
Prevalence of aortic valve abnormalities in the elderly: An echocardiographic study of a random population sample
Lindroos, M., Kupari, M. M., Heikkilä, J., & Tilvis, R. S. (1993) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(93)90249-z · Cited by 1,148
Self-citation
Prospective Study of Asymptomatic Valvular Aortic Stenosis: Clinical, Echocardiographic, and Exercise Predictors of Outcome
Otto, C. M., Burwash, I. G., Legget, M. E., Munt, B. I., Fujioka, M., Healy, N. L., Kraft, C. D., Miyake-Hull, C. Y., & Schwaegler, R. G. (1997) · Circulation · doi:10.1161/01.cir.95.9.2262 · Cited by 1,146
Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., de Leon, A. C., Edmunds, L. H., Fedderly, B. J., Freed, M. D., Gaasch, W. H., McKay, C. R., Nishimura, R. A., O’Gara, P. T., et al. (1998) · Circulation · doi:10.1161/01.cir.98.18.1949 · Cited by 1,026
Hypertrophy of the Heart
Frey, N., Katus, H. A., Olson, E. N., & Hill, J. A. (2004) · Circulation · doi:10.1161/01.cir.0000120390.68287.bb · Cited by 859
Standardization of M-mode echocardiographic left ventricular anatomic measurements
Devereux, R. B., Lutas, E. M., Casale, P. N., Kligfield, P., Eisenberg, R. R., Hammond, I. W., Miller, D. H., Reis, G. J., Alderman, M. H., & Laragh, J. H. (1984) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(84)80141-2 · Cited by 742

Show all 40 references

Research works printed but not linked: 1

The Task Force on Heart Failure of the European Society of Cardiology. Guidelines for the diagnosis of heart failure. Eur Heart J1995;16:741–751.

Sorted by citations

Calcific aortic stenosis
Lindman, B. R., Clavel, M.-A., Mathieu, P., Iung, B., Lancellotti, P., Otto, C. M., & Pibarot, P. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.6 · Cited by 982
Controversies in ventricular remodelling
Opie, L. H., Commerford, P., Gersh, B. J., & Pfeffer, M. A. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68074-4 · Cited by 856
Aortic stenosis
Carabello, B. A., & Paulus, W. J. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60211-7 · Cited by 818
Calcific Aortic Stenosis
Dweck, M. R., Boon, N. A., & Newby, D. E. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.02.093 · Cited by 692
Noninvasive Detection of Fibrosis Applying Contrast-Enhanced Cardiac Magnetic Resonance in Different Forms of Left Ventricular Hypertrophy
Rudolph, A., Abdel‐Aty, H., Bohl, S., Boyé, P., Zagrosek, A., Dietz, R., & Schulz‐Menger, J. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.08.064 · Cited by 384
Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy
Abel, E. D., & Doenst, T. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr015 · Cited by 263
Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload
Doenst, T., Pytel, G., Schrepper, A., Amorim, P., Färber, G., Shingu, Y., Mohr, F. W., & Schwarzer, M. (2009) · Cardiovascular Research · doi:10.1093/cvr/cvp414 · Cited by 246
Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance
Dweck, M. R., Joshi, S., Murigu, T., Gulati, A., Alpendurada, F., Jabbour, A., Maceira, A. M., Roussin, I., Northridge, D. B., Kilner, P. J., et al. (2012) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-14-50 · Cited by 232
Current Management of Calcific Aortic Stenosis
Lindman, B. R., Bonow, R. O., & Otto, C. M. (2013) · Circulation Research · doi:10.1161/circresaha.111.300084 · Cited by 175
Introduction to Aortic Stenosis
Carabello, B. A. (2013) · Circulation Research · doi:10.1161/circresaha.113.300156 · Cited by 164
The Myocardial Oxygen Supply:Demand Index Revisited
Hoffman, J. I. E., & Buckberg, G. D. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.113.000285 · Cited by 160
Prognostic value of myocardial fibrosis in patients with severe aortic valve stenosis
Milano, A. D., Faggian, G. G., Dodonov, M., Golia, G., Tomezzoli, A., Bortolotti, U., & Mazzucco, A. (2012) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2011.11.024 · Cited by 134
Early Cardiac Remodeling Promotes Tumor Growth and Metastasis
Avraham, S., Abu-Sharki, S., Shofti, R., Haas, T., Korin, B., Kalfon, R., Friedman, T., Shiran, A., Saliba, W., Shaked, Y., et al. (2020) · Circulation · doi:10.1161/circulationaha.120.046471 · Cited by 135
Aortic valve stenosis: an active atheroinflammatory process
Helske, S., Kupari, M. M., Lindstedt, K. A., & Kovanen, P. T. (2007) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3282a66099 · Cited by 143
Self-citation
Diagnostic and prognostic value of cardiovascular magnetic resonance in non-ischaemic cardiomyopathies
Parsai, C., O’Hanlon, R., Prasad, S., & Mohiaddin, R. H. (2012) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-14-54 · Cited by 133
Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves
Helske, S., Syväranta, S., Kupari, M., Lappalainen, J., Laine, M., Lommi, J., Turto, H., Mäyränpää, M., Werkkala, K., Kovanen, P. T., et al. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehi706 · Cited by 129
Self-citation
Maladaptive Remodeling Is Associated With Impaired Survival in Women But Not in Men After Aortic Valve Replacement
Petrov, G., Dworatzek, E., Schulze, T. M., Dandel, M., Kararigas, G., Mahmoodzadeh, S., Knosalla, C., Hetzer, R., & Regitz‐Zagrosek, V. (2014) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2014.06.017 · Cited by 111
Management of Asymptomatic Severe Aortic Stenosis
Lindman, B. R., Dweck, M. R., Lancellotti, P., Généreux, P., Piérard, L., O’Gara, P. T., & Bonow, R. O. (2019) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2019.01.036 · Cited by 108
RV pressure overload: from hypertrophy to failure
van der Bruggen, C. E. E., Tedford, R. J., Handoko, M. L., van der Velden, J., & de Man, F. S. (2017) · Cardiovascular Research · doi:10.1093/cvr/cvx145 · Cited by 105
Left Ventricular Hypertrophy in Valvular Aortic Stenosis: Mechanisms and Clinical Implications
Rader, F., Sachdev, E., Arsanjani, R., & Siegel, R. J. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.10.054 · Cited by 99
A clinical risk score of myocardial fibrosis predicts adverse outcomes in aortic stenosis
Chin, C., Messika–Zeitoun, D., Shah, A. S. V., Lefèvre, G., Bailleul, S., Yeung, E., Koo, M., Mirsadraee, S., Mathieu, T., Semple, S. I. K., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv525 · Cited by 98
Determinants and Functional Significance of Myocardial Perfusion Reserve in Severe Aortic Stenosis
Steadman, C. D., Jerosch‐Herold, M., Grundy, B., Rafelt, S. E., Ng, L. L., Squire, I. B., Samani, N. J., & McCann, G. P. (2012) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2011.09.022 · Cited by 97
Mechanisms of Cardiac Contraction and Relaxation
Opie, L. H., & Hasenfuss, G. P. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0398-6.00024-x · Cited by 97
Symptom Onset in Aortic Stenosis
Singh, A., Chan, D. C. S., Greenwood, J. P., Dawson, D. K., Sonecki, P., Hogrefe, K., Kelly, D. J., Dhakshinamurthy, V. A., Lang, C. C., Khoo, J. P., et al. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.09.019 · Cited by 96
Adverse Left Ventricular Remodeling in Community-Dwelling Older Adults Predicts Incident Heart Failure and Mortality
Zile, M. R., Gaasch, W. H., Patel, K., Aban, I., & Ahmed, A. (2014) · JACC Heart Failure · doi:10.1016/j.jchf.2014.03.016 · Cited by 87
Asymptomatic Aortic Stenosis in the Elderly
Manning, W. J. (2013) · JAMA · doi:10.1001/jama.2013.279194 · Cited by 77
Left Ventricular Diastolic Function Is Associated With Symptom Status in Severe Aortic Valve Stenosis
Dahl, J. S., Christensen, N. L., Videbæk, L. M., Poulsen, M. K., Carter‐Storch, R., Hey, T. M., Pellikka, P. A., Steffensen, F. H., & Møller, J. E. (2013) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.113.000636 · Cited by 76
Left Ventricular Remodelling in Aortic Stenosis
Rassi, A. N., Pîbarot, P., & Elmariah, S. (2014) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.04.026 · Cited by 75
The Adverse Impact of Diabetes Mellitus on Left Ventricular Remodeling and Function in Patients With Severe Aortic Stenosis
Lindman, B. R., Arnold, S. V., Madrazo, J. A., Zajarias, A., Johnson, S. N., Pérez, J. E., & Mann, D. L. (2011) · Circulation: Heart Failure · doi:10.1161/circheartfailure.110.960039 · Cited by 68
Aortic Valve Replacement Should Be Operated on Before Symptom Onset
Carabello, B. A. (2012) · Circulation · doi:10.1161/circulationaha.111.079350 · Cited by 67
Early Diastolic Strain Rate in Relation to Systolic and Diastolic Function and Prognosis in Aortic Stenosis
Dahl, J. S., Barros‐Gomes, S., Videbæk, L. M., Poulsen, M. K., Issa, I. F., Carter‐Storch, R., Christensen, N. L., Kumme, A., Pellikka, P. A., & Møller, J. E. (2016) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2015.06.029 · Cited by 64
Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway
Pellieux, C., Aasum, E., Larsen, T. S., Montessuit, C., Papageorgiou, I., Pedrazzini, T., & Lerch, R. A. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2006.06.004 · Cited by 61
Aortic Valve Area, Stroke Volume, Left Ventricular Hypertrophy, Remodeling, and Fibrosis in Aortic Stenosis Assessed by Cardiac Magnetic Resonance Imaging
Barone‐Rochette, G., Piérard, S., Seldrum, S., de Meester, C., Melchior, J., Maes, F., Pouleur, A., Vancraeynest, D., Pasquet, A., Vanoverschelde, J., et al. (2013) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.113.000515 · Cited by 61
Towards a Re-Definition of ‘Cardiac Hypertrophy’ Through a Rational Characterization of Left Ventricular Phenotypes: A Position Paper of the Working Group ‘Myocardial Function’ of the ESC
Knöll, R., Iaccarino, G., Tarone, G., Hilfiker‐Kleiner, D., Bauersachs, J. K., Leite-Moreira, A. F., Sugden, P. H., & Balligand, J. (2011) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfr071 · Cited by 59
Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves
Helske, S., Miettinen, T. A., Gylling, H., Mäyränpää, M. I., Lommi, J., Turto, H., Werkkala, K., Kupari, M. M., & Kovanen, P. T. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800058-jlr200 · Cited by 58
Self-citation
Circulating Levels of miR‐133a Predict the Regression Potential of Left Ventricular Hypertrophy After Valve Replacement Surgery in Patients With Aortic Stenosis
García, R., Villar, A. V., Cobo, M., Llano, M., Martín‐Durán, R., Hurlé, M. A., & Nistal, J. F. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.113.000211 · Cited by 53
Impact of the left ventricular mass index on the outcomes of severe aortic stenosis
Minamino‐Muta, E., Kato, T., Morimoto, T., Taniguchi, T., Inoko, M., Haruna, T., Izumi, T., Miyamoto, S., Nakane, E., Sasaki, K., et al. (2017) · Heart · doi:10.1136/heartjnl-2016-311022 · Cited by 52
Increased Circulating Concentrations and Augmented Myocardial Extraction of Osteoprotegerin in Heart Failure Due to Left Ventricular Pressure Overload
Helske, S., Kovanen, P. T., Lindstedt, K. A., Salmela, K. T., Lommi, J., Turto, H., Werkkala, K., & Kupari, M. M. (2007) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2006.10.015 · Cited by 47
Self-citation
Left Ventricular Hypertrophy and Clinical Outcomes Over 5 Years After TAVR
Gonzales, H. M., Douglas, P. S., Pîbarot, P., Hahn, R. T., Khalique, O. K., Jaber, W. A., Cremer, P. C., Weissman, N. J., Asch, F. M., Zhang, Y., et al. (2020) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2020.03.011 · Cited by 47
The dynamic interplay between cardiac mitochondrial health and myocardial structural remodeling in metabolic heart disease, aging, and heart failure
Werbner, B., Tavakoli‐Rouzbehani, O. M., Fatahian, A. N., & Boudina, S. (2023) · The Journal of Cardiovascular Aging · doi:10.20517/jca.2022.42 · Cited by 44
Impact of Afterload Increase on Left Ventricular Myocardial Deformation Indices
Réant, P., Métras, A., Détaille, D., Reynaud, A., Diolez, P., Jaspard‐Vinassa, B., Roudaut, R. P., Ouattara, A., Barandon, L., Santos, P. D. D., et al. (2016) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2016.09.006 · Cited by 45
Echocardiographic Assessment of Cardiac Structural and Functional Abnormalities in Patients With End-Stage Renal Disease Receiving Chronic Hemodialysis
Matsuo, H., Dohi, K., Machida, H., Takeuchi, H., Aoki, T., Nishimura, H., Yasutomi, M., Senga, M., Ichikawa, T., Kakuta, K., et al. (2017) · Circulation Journal · doi:10.1253/circj.cj-17-0393 · Cited by 45
Left Ventricular Mass Regression One Year After Transcatheter Aortic Valve Implantation
Tzikas, A., Geleijnse, M. L., Mieghem, N. M. V., Schultz, C. J., Nuis, R.-J. M., van Dalen, B. M., Sarno, G., van Domburg, R. T., Serruys, P. W. J. C., & de Jaegere, P. P. T. (2011) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2010.09.037 · Cited by 44
GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement
Kim, J. B., Kobayashi, Y., Moneghetti, K. J., Brenner, D. A., O’Malley, R., Schnittger, I., Wu, J. C., Murtagh, G., Beshiri, A., Fischbein, M. P., et al. (2017) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.117.005594 · Cited by 42
Evaluation of Tp‐E Interval and Tp‐E/QT Ratio in Patients with Aortic Stenosis
Yayla, Ç., Bilgin, M., Akboğa, M. K., Yayla, K. G., Canpolat, U., Asarcıklı, L. D., Doğan, M., Turak, O., Çay, S., Özeke, Ö., et al. (2015) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.12298 · Cited by 41
Aortic morphological variability in patients with bicuspid aortic valve and aortic coarctation
Sophocleous, F., Biffi, B., Milano, E. G., Bruse, J. L., Caputo, M., Rajakaruna, C., Schievano, S., Emanueli, C., Bucciarelli‐Ducci, C., & Biglino, G. (2018) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy339 · Cited by 41
Clinical outcome 5 to 18 years after the Fontan operation performed on children younger than 5 years
Robbers‐Visser, D., Kapusta, L., van Osch-Gevers, L. M., Strengers, J. L. M., Boersma, E. H., de Rijke, Y. B., Boomsma, F., Bogers, A. J. J. C., & Helbing, W. A. (2009) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2008.12.027 · Cited by 39
Left Ventricular Hypertrophy and Biomarkers of Cardiac Damage and Stress in Aortic Stenosis
Stein, E. J., Fearon, W. F., Elmariah, S., Kim, J. B., Kapadia, S. R., Kumbhani, D. J., Gillam, L., Whisenant, B., Quader, N., Zajarias, A., et al. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.121.023466 · Cited by 41
Selective homocysteine-lowering gene transfer attenuates pressure overload-induced cardiomyopathy via reduced oxidative stress
Muthuramu, I., Singh, N., Amin, R., Nefyodova, E., Debasse, M., Horenbeeck, I. V., Jacobs, F., & Geest, B. D. (2015) · Journal of Molecular Medicine · doi:10.1007/s00109-015-1281-3 · Cited by 38
Increased expression of profibrotic neutral endopeptidase and bradykinin type 1 receptors in stenotic aortic valves
Helske, S., Laine, M., Kupari, M. M., Lommi, J., Turto, H., Nurmi, L., Tikkanen, I. T., Werkkala, K., Lindstedt, K. A., & Kovanen, P. T. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm129 · Cited by 38
Self-citation
Circulating Level of miR-378 Predicts Left Ventricular Hypertrophy in Patients with Aortic Stenosis
Chen, Z., Li, C., Xu, Y., Li, Y., Yang, H., & Rao, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105702 · Cited by 36
Myocardial efficiency is an important determinant of functional improvement after aortic valve replacement in aortic valve stenosis patients: a combined PET and CMR study
Güçlü, A., Knaapen, P., Harms, H. J., Vonk, A. B. A., Stooker, W., Groepenhoff, H., Lammertsma, A. A., van Rossum, A. C., Germans, T., & van der Velden, J. (2015) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jev009 · Cited by 36
Factors affecting left ventricular remodeling after valve replacement for aortic stenosis. An overview
Villa, E., Troise, G., Cirillo, M., Brunelli, F., Tomba, M. D., Mhagna, Z., Tasca, G., & Quaini, E. (2006) · Cardiovascular Ultrasound · doi:10.1186/1476-7120-4-25 · Cited by 34
Cardiac Microvascular Endothelial Cells in Pressure Overload–Induced Heart Disease
Trenson, S., Hermans, H., Craps, S., Pokreisz, P., de Zeeuw, P., Wauwe, J. V., Gillijns, H., Veltman, D., Wei, F., Caluwé, E., et al. (2021) · Circulation Heart Failure · doi:10.1161/circheartfailure.120.006979 · Cited by 32
Left ventricular remodelling patterns in patients with moderate aortic stenosis
Stassen, J., Ewe, S. H., Hirasawa, K., Butcher, S. C., Singh, G. K., Amanullah, M. R., Sin, K. Y. K., Ding, Z. P., Pio, S. M., Chew, N., et al. (2022) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeac018 · Cited by 30
Preoperative tissue Doppler imaging differentiates beneficial from detrimental left ventricular hypertrophy in patients with surgical aortic stenosis. A postoperative morbidity study
Bauer, F., Mghaieth, F., Dervaux, N., Donal, E., Dérumeaux, G., Cribier, A. G., & Bessou, J. P. (2008) · Heart · doi:10.1136/hrt.2007.121442 · Cited by 30
Discrepancies in Left Ventricular Mass Calculation Based on Echocardiography and Cardiovascular Magnetic Resonance Measurements in Patients with Left Ventricular Hypertrophy
Seo, H.-Y., Lee, S., Park, J.-B., Lee, J. M., Park, E.-A., Chang, S.-A., Kim, H.-K., Park, S.-J., Lee, W., Kim, Y.-J., et al. (2015) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2015.06.009 · Cited by 27
Comparison of calcification potential of valvular interstitial cells isolated from individual aortic valve cusps
Masjedi, S., Amarnath, A., Baily, K. M., & Ferdous, Z. (2015) · Cardiovascular Pathology · doi:10.1016/j.carpath.2015.12.002 · Cited by 27
Pressure overload-induced right ventricular dysfunction and remodelling in experimental pulmonary hypertension: the right heart revisited
Pokreisz, P., Marsboom, G., & Janssens, S. P. (2007) · European Heart Journal Supplements · doi:10.1093/eurheartj/sum021 · Cited by 27
Rationale and design of the PRognostic Importance of MIcrovascular Dysfunction in asymptomatic patients with Aortic Stenosis (PRIMID-AS): a multicentre observational study with blinded investigations
Singh, A., Ford, I., Greenwood, J. P., Khan, J. N., Uddin, A., Berry, C., Neubauer, S., Prendergast, B., Jerosch‐Herold, M., Williams, B., et al. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-004348 · Cited by 26
Markers of left ventricular decompensation in aortic stenosis
Chin, C. W., Vassiliou, V. S., Jenkins, W. S. A., Prasad, S. K., Newby, D. E., & Dweck, M. R. (2014) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.2014.923307 · Cited by 28
Outcome of Left-Sided Cardiac Remodeling in Severe Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Implantation
Magalhães, M. A., Koifman, E., Torguson, R., Minha, S., Gai, J., Kiramijyan, S., Escarcega, R. O., Baker, N. C., Wang, Z., Goldstein, S., et al. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.05.018 · Cited by 26
Is the use of renin–angiotensin system inhibitors in patients with aortic valve stenosis safe and of prognostic benefit? A systematic review and meta-analysis
Andersson, C., & Abdulla, J. (2016) · European Heart Journal - Cardiovascular Pharmacotherapy · doi:10.1093/ehjcvp/pvw027 · Cited by 26
MicroRNA profiling identifies miR-7-5p and miR-26b-5p as differentially expressed in hypertensive patients with left ventricular hypertrophy
Kaneto, C. M., Nascimento, J. S., Moreira, M. C. R., Ludovico, N. D., Santana, A. P., Silva, R. A. A., Silva-Jardim, I., dos Santos, J. L., Sousa, S. M. B., & Lima, P. (2017) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20176211 · Cited by 24
Strain Assessment in Aortic Stenosis: Pathophysiology and Clinical Utility
Meredith, T., Roy, D. A., Hayward, C., Feneley, M. P., Kovacic, J. C., Muller, D. W., & Namasivayam, M. J. (2023) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2023.10.001 · Cited by 23
Calcific Aortic Valve Disease: Part 2—Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility
Pasipoularides, A. D. (2016) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-016-9695-z · Cited by 23
The Pathophysiology of Afterload Mismatch and Ventricular Hypertrophy
Carabello, B. A. (2021) · Structural Heart · doi:10.1080/24748706.2021.1944708 · Cited by 23
How Does the Heart Respond to Aortic Stenosis
Carabello, B. A. (2013) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.113.001242 · Cited by 23
Left Ventricular Remodeling in Degenerative Aortic Valve Stenosis
Abecasis, J., Pinto, D. G., Ramos, S., Masci, P. G., Cardim, N. M., Gil, V. M., & Félix, A. (2021) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2021.100801 · Cited by 22
Aortic Stenosis: A Contemporary Review
Sawaya, F., Liff, D. A., Stewart, J. T., Lerakis, S., Babaliaros, V. C., & Lerakis, S. (2012) · The American Journal of the Medical Sciences · doi:10.1097/maj.0b013e3182539d70 · Cited by 22
Is Blockade of the Renin-angiotensin System Able to Reverse the Structural and Functional Remodeling of the Left Ventricle in Severe Aortic Stenosis?
Suihko, S., Laine, M., Lommi, J., Kaartinen, M., Werkkala, K., Kovanen, P. T., & Kupari, M. M. (2014) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000182 · Cited by 22
Self-citation
Impact of Associated Significant Aortic Regurgitation on Left Ventricular Remodeling and Hemodynamic Impairment in Severe Aortic Valve Stenosis
Popescu, A. C., Antonini‐Canterin, F., Enache, R., Nicolosi, G. L., Piazza, R., Faggiano, P. M., Cassin, M., Dimulescu, D. R., Ginghină, C., & Popescu, B. A. (2013) · Cardiology · doi:10.1159/000346623 · Cited by 22
Prognostic value of pre-procedural left ventricular strain for clinical events after transcatheter aortic valve implantation
Suzuki-Eguchi, N., Murata, M., Itabashi, Y., Shirakawa, K., Fukuda, M., Endo, J., Tsuruta, H., Arai, T., Hayashida, K., Shimizu, H., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0205190 · Cited by 21
The role of cardiac biochemical markers in aortic stenosis
Chin, C., Djohan, A. H., & Lang, C. C. (2016) · Biomarkers · doi:10.3109/1354750x.2016.1141993 · Cited by 22
Echocardiographic predictors of left ventricular functional recovery following valve replacement surgery for severe aortic stenosis
Ding, W., Lam, Y., Kaya, M. G., Li, W., Chung, R., Pepper, J., & Henein, M. Y. (2007) · International Journal of Cardiology · doi:10.1016/j.ijcard.2007.05.025 · Cited by 20
Patterns of Left Ventricular Remodeling in Aortic Stenosis: Therapeutic Implications
Elmariah, S. (2015) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-015-0391-0 · Cited by 20
Early hemodynamic changes after transcatheter aortic valve implantation in patients with severe aortic stenosis measured by invasive pressure volume loop analysis
Seppelt, P. C., Rosa, R. D., Mas‐Peiró, S., Zeiher, A. M., & Vasa‐Nicotera, M. (2020) · Cardiovascular Intervention and Therapeutics · doi:10.1007/s12928-020-00737-4 · Cited by 19
Bicuspid aortic valve in pregnancy
Yuan, S. (2014) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2013.06.018 · Cited by 19
Plasma Fibulin‐1 Is Linked to Restrictive Filling of the Left Ventricle and to Mortality in Patients With Aortic Valve Stenosis
Dahl, J. S., Møller, J. E., Videbæk, L. M., Poulsen, M. K., Rudbæk, T. R., Pellikka, P. A., Argraves, W. S., & Rasmussen, L. M. (2012) · Journal of the American Heart Association · doi:10.1161/jaha.112.003889 · Cited by 18
Impact of gender on outcomes after transcatheter aortic valve implantation
Yousif, N., Obeid, S., Binder, R. K., Denegri, A., Shahin, M., Templin, C., & Lüscher, T. F. (2018) · Europe PMC (PubMed Central) · doi:10.5167/uzh-162642 · Cited by 18
Transcatheter aortic valve replacement (TAVR) leads to an increase in the subendocardial viability ratio assessed by pulse wave analysis
Müller, C., Goliasch, G., Schachinger, S., Kastl, S., Neunteufl, T., Delle‐Karth, G., Kästner, J., Gyöngyösi, M., Lang, I. M., Gottsauner‐Wolf, M., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207537 · Cited by 18
The impact of global left ventricular afterload on left ventricular reverse remodeling after aortic valve replacement
Ito, H., Mizumoto, T., Shomura, Y., Sawada, Y., Kajiyama, K., & Shimpo, H. (2017) · Journal of Cardiac Surgery · doi:10.1111/jocs.13190 · Cited by 17
Cardiac Adaptation to Volume Overload
Melenovský, V. (2012) · Springer eBooks · doi:10.1007/978-1-4614-5203-4_9 · Cited by 17
Echocardiographic and Histologic Correlations in Patients with Severe Aortic Stenosis: Influence of Overweight and Obesity
Ávila‐Vanzzini, N., Fritche‐Salazar, J. F., Vázquez-Castro, N. M., Rivera-Lara, P., Pérez-Méndez, O. A., Martínez-Herrera, H., Gómez-Sánchez, M., Aranda‐Frausto, A., Herrera-Bello, H., Luna‐Luna, M., et al. (2016) · Journal of Cardiovascular Ultrasound · doi:10.4250/jcu.2016.24.4.303 · Cited by 16
Predicting and measuring mortality risk after transcatheter aortic valve replacement
Gupta, T., Joseph, D. T., Goel, S. S., & Kleiman, N. S. (2021) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2021.1888715 · Cited by 15
Circulatory efficiency in patients with severe aortic valve stenosis before and after aortic valve replacement
Nordmeyer, S., Lee, C. B., Goubergrits, L., Knosalla, C., Berger, F. F., Falk, V., Ghorbani, N., Hireche-Chikaoui, H., Zhu, M., Kelle, S., et al. (2021) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/s12968-020-00686-0 · Cited by 15
Impact of Valvuloarterial Impedance on Concentric Remodeling in Aortic Stenosis and Its Regression after Valve Replacement
Jang, J. Y., Seo, J.-S., Sun, B. J., Kim, D., Song, J., Kang, D., & Song, J. (2016) · Journal of Cardiovascular Ultrasound · doi:10.4250/jcu.2016.24.3.201 · Cited by 15
Cytokines profile of reverse cardiac remodeling following transcatheter aortic valve replacement
Kim, J. B., Kobayashi, Y., Kuznetsova, T., Moneghetti, K. J., Brenner, D. A., O'Malley, R., Dao, C. N., Wu, J. C., Fischbein, M. P., Miller, D. C., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.05.020 · Cited by 15
Established and emerging vascular risk factors and the development of aortic stenosis: an opportunity for prevention?
Τζιόμαλος, Κ., Athyros, V. G., Karagiannis, A. I., & Mikhailidis, D. P. (2008) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.12.7.809 · Cited by 15
Transcardiac gradients of circulating apelin: extraction by normal hearts vs. release by hearts failing due to pressure overload
Helske, S., Kovanen, P. T., Lommi, J., Turto, H., & Kupari, M. M. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00474.2010 · Cited by 15
Self-citation
Ascending aorta dilatation in patients with bicuspid aortic valve stenosis: a prospective CMR study
Rossi, A., van der Linde, D., Yap, S., Lapinskas, T., Kirschbaum, S. W., Springeling, T., Witsenburg, M., Cuypers, J. A. A. E., Moelker, A. D., Krestin, G. P., et al. (2012) · European Radiology · doi:10.1007/s00330-012-2651-7 · Cited by 14
Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Healthy Subjects, Aortic Stenosis and Aortic Coarctation Patients–A Systematic Review and Meta-Analysis
Runte, K., Brosien, K., Salcher‐Konrad, M., Schubert, C., Goubergrits, L., Kelle, S., Schubert, S., Berger, F. F., Kühne, T., & Kelm, M. (2019) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2019.00043 · Cited by 14
Left ventricular mass regression after sutureless implantation of the Perceval S aortic valve bioprosthesis: preliminary results
Santarpino, G., Pfeiffer, S., Pollari, F., Concistrè, G., Vogt, F. A., & Fischlein, T. J. M. (2013) · Interactive Cardiovascular and Thoracic Surgery · doi:10.1093/icvts/ivt362 · Cited by 14
Congenital valvular aortic stenosis in young adults: Predictors for rate of progression of stenosis and aortic dilatation
van der Linde, D., Andrinopoulou, E.-R., Oechslin, E. N., Budts, W., van Dijk, A. P. J., Pieper, P. G., Wajon, E. M. C. J., Post, M. C., Witsenburg, M., Silversides, C. K., et al. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.10.027 · Cited by 14
Sad Heart From No SOD
Góngora, M. C., & Harrison, D. G. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.101162 · Cited by 14
Advances in the Understanding of the Pathophysiology and Management of Aortic Stenosis: Role of Novel Imaging Techniques
Singh, A., Steadman, C. D., & McCann, G. P. (2014) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.03.008 · Cited by 13
Epicardial adipose tissue volume is associated with left ventricular remodelling in calcific aortic valve stenosis
Arangalage, D., Mathieu, T., Nguyen, V., Cimadevilla, C., Kerneis, C., Duval, X., Tubiana, S., Hyafil, F., Ou, P., Tribouilloy, C. M., et al. (2019) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2019.06.005 · Cited by 13
Antihypertensive therapies in moderate or severe aortic stenosis: a systematic review and meta-analysis
Sen, J., Chung, E., Neil, C., & Marwick, T. H. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-036960 · Cited by 13
Noninvasive cardiac output monitoring during general anesthesia for Cesarean delivery in a patient with severe aortic stenosis
Fanning, N., Balki, M., Sermer, M., Colman, J. M., & Carvalho, J. C. A. (2011) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-011-9537-z · Cited by 13
Influence of Myocardial Fibrosis on Left Ventricular Hypertrophy in Patients with Symptomatic Severe Aortic Stenosis
Golia, G., Milano, A. D., Dodonov, M., Bergamini, C., Faggian, G. G., Tomezzoli, A., & Vassanelli, C. (2011) · Cardiology · doi:10.1159/000334792 · Cited by 13

Authors: Kupari, M., Turto, H., & Lommi, J.
Affiliations: Helsinki University Hospital (FI)
Corresponding author: Kupari, Markku
ORCID: Kupari, Markku
Lommi, Jyri
Venue: European Heart Journal
Publisher: Oxford University Press (OUP)
Published: 2005-04-28
Volume: 26
Issue: 17
Pages: 1790-1796
ISSN: 0195-668X (ISSN-L)
1522-9645
DOI: 10.1093/eurheartj/ehi290
OpenAlex: W2123889844
Cited by: 233
References: 40
Citations by year: 2026: 6 · 2025: 9 · 2024: 8 · 2023: 10 · 2022: 8 · 2021: 13 · 2020: 15 · 2019: 15 · 2018: 16 · 2017: 14 · 2016: 11 · 2015: 14 · 2014: 16 · 2013: 17 · 2012: 16
FWCI: 5.02
Type: journal article
Language: en
Open access: closed
Locations: European Heart Journal (publishedVersion)
PubMed (publishedVersion)
HighWire Press Open Archive (submittedVersion)
Funders: Foundation for Cardiovascular Research
Helsingin ja Uudenmaan Sairaanhoitopiiri
Sydäntutkimussäätiö
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Keywords: aortic stenosis, left ventricular hypertrophy, left ventricular mass, heart failure, systolic dysfunction, ejection fraction, valvular obstruction, maladaptive hypertrophy, compensatory response
MeSH terms: Adaptation, Physiological, Adult, Aged, Aged, 80 and over, Aortic Valve Stenosis, Female, Cardiac Catheterization, Heart Failure, Hemodynamics, Humans, Male, Middle Aged, Postoperative Period, Stroke Volume, Ultrasonography, Hypertrophy, Left Ventricular

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Left ventricular hypertrophy in aortic valve stenosis: preventive or promotive of systolic dysfunction and heart failure?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks