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Increased Short-Term Variability of the QT Interval in Professional Soccer Players: Possible Implications for Arrhythmia Prediction

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Increased Short-Term Beat-to-Beat QT Interval Variability in Patients with Impaired Glucose Tolerance

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Short‐Term Variability of the QT Interval Can be Used for the Prediction of Imminent Ventricular Arrhythmias in Patients With Primary Prophylactic Implantable Cardioverter Defibrillators

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PDE5 Inhibition Suppresses Ventricular Arrhythmias by Reducing SR Ca 2+ Content

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Handling of Ventricular Fibrillation in the Emergency Setting

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Keeping the rhythm: hERG and beyond in cardiovascular safety pharmacology

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Beat-to-Beat Variability in Preload Unmasks Latent Risk of Torsade de Pointes in Anesthetized Chronic Atrioventricular Block Dogs

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Towards a better understanding of QT interval variability

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The Increment of Short-term Variability of Repolarisation Determines the Severity of the Imminent Arrhythmic Outcome

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Role of Gap Junction Channel in the Development of Beat-to-Beat Action Potential Repolarization Variability and Arrhythmias

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Reduced Ventricular Proarrhythmic Potential of the Novel Combined Ion-Channel Blocker AZD1305 Versus Dofetilide in Dogs With Remodeled Hearts

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Predicting Drug‐Induced QT Prolongation and Torsades de Pointes: A Review of Preclinical Endpoint Measures

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Transgenic Rabbit Models in Proarrhythmia Research

Baczkó, I., Hornyik, T., Brunner, M. P., Koren, G., & Odening, K. E. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00853 · Cited by 13 · see citing works

The combined ion channel blocker AZD1305 attenuates late Na current and IKr-induced action potential prolongation and repolarization instability

Andersson, B., Abi‐Gerges, N., & Carlsson, L. G. (2010) · EP Europace · doi:10.1093/europace/euq070 · Cited by 13 · see citing works

Instability of repolarization in LQTS mutation carriers compared to healthy control subjects assessed by vectorcardiography

Vahedi, F., Diamant, U., Lundahl, G., Bergqvist, G., Gransberg, L., Jensen, S. M., & Bergfeldt, L. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.05.001 · Cited by 11 · see citing works

Pro-Arrhythmic Ventricular Remodeling Is Associated With Increased Respiratory and Low-Frequency Oscillations of Monophasic Action Potential Duration in the Chronic Atrioventricular Block Dog Model

Sprenkeler, D. J., Beekman, J. D. M., Bossu, A., Dunnink, A., & Vos, M. A. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01095 · Cited by 11 · see citing works

Genotype-Specific ECG-Based Risk Stratification Approaches in Patients With Long-QT Syndrome

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Circadian pattern of short-term variability of the QT-interval in primary prevention ICD patients - EU-CERT-ICD methodological pilot study

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Modeling and Simulation of Preclinical Cardiac Safety: Towards an Integrative Framework

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Cardiac regulation and electrocardiographic factors contributing to the measurement of repolarization variability

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Polymorphic Ventricular Tachycardia—Part I: Structural Heart Disease and Acquired Causes

Choudhuri, I., Pinninti, M., Marwali, M. R., Sra, J. S., & Akhtar, M. (2013) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2013.07.001 · Cited by 10 · see citing works

Automatic identification of a stable QRST complex for non-invasive evaluation of human cardiac electrophysiology

Lundahl, G., Gransberg, L., Bergqvist, G., Bergström, G. M. L., & Bergfeldt, L. (2020) · PLoS ONE · doi:10.1371/journal.pone.0239074 · Cited by 10 · see citing works

Beat-to-Beat Variability in Field Potential Duration in Human Embryonic Stem Cell-Derived Cardiomyocyte Clusters for Assessment of Arrhythmogenic Risk, and a Case Study of Its Application

Yamazaki, K., Hihara, T., Kato, H., Fukushima, T., Fukushima, K., Taniguchi, T., Yoshinaga, T., Miyamoto, N., Ito, M., & Sawada, K. (2014) · Pharmacology &amp Pharmacy · doi:10.4236/pp.2014.51017 · Cited by 8 · see citing works

DeltaT50—a new method to assess temporal ventricular repolarization variability

Abrahamsson, C., Dota, C., Skallefell, B., Carlsson, L. M. S., Halawani, D., Frison, L., Berggren, A., Edvardsson, N. G., & Duker, G. (2011) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2011.04.010 · Cited by 7 · see citing works

An increasing electromechanical window is a predictive marker of ventricular fibrillation in anesthetized rabbit with ischemic heart

Limprasutr, V., Pirintr, P., Kijtawornrat, A., & Hamlin, R. L. (2017) · EXPERIMENTAL ANIMALS · doi:10.1538/expanim.17-0100 · Cited by 7 · see citing works

Beat‐to‐beat QT interval variability as a tool to detect the underlying cellular mechanisms of arrhythmias

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qInward variability-based in-silico proarrhythmic risk assessment of drugs using deep learning model

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Utility of Short-Term Variability of Repolarization as a Marker for Monitoring a Safe Exercise Training Program in Patients With Cardiac Diseases

Nishi, I., Sugiyama, A., Takahara, A., Kuroki, K., Igawa, M., Enomoto, T., Iida, K., Koseki, S., & Aonuma, K. (2011) · International Heart Journal · doi:10.1536/ihj.52.304 · Cited by 6 · see citing works

Implication of frequency-dependent protocols in antiarrhythmic and proarrhythmic drug testing

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Role of dynamical instability in QT interval variability and early afterdepolarization propensity

Sato, D., Hegyi, B., Ripplinger, C. M., & Bers, D. M. (2025) · Biophysical Journal · doi:10.1016/j.bpj.2025.07.017 · Cited by 5 · see citing works

Electrocardiographic Markers of Repolarization Heterogeneity During Dofetilide or Sotalol Initiation for Paroxysmal Atrial Fibrillation

Sauer, A. J., Kaplan, R. M., Xue, J. Q., Dorsey, P., Hayes, M., Shah, S. J., & PASSMAN, R. S. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.03.047 · Cited by 5 · see citing works

Inhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction

Citerni, C., Kirchhoff, J. E., Olsen, L. H., Sattler, S. M., Grunnet, M., Edvardsson, N. G., Bentzen, B. H., & Diness, J. G. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00556 · Cited by 5 · see citing works

Improved ECG pre-processing for beat-to-beat QT interval variability measurement

Hasan, M. A., Starc, V., Porta, A., Abbott, D., & Baumert, M. (2013) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6610063 · Cited by 5 · see citing works

Latent microvolt T-wave alternans in survivors of unexplained cardiac arrest unmasked by epinephrine challenge

SPEARS, D. A., Suszko, A. M., Krahn, A. D., Selvaraj, R. J., Ivanov, J., & Chauhan, V. S. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2012.02.026 · Cited by 5 · see citing works

The Conventional Antihistamine Drug Cyproheptadine Lacks QT-interval–Prolonging Action in Halothane-Anesthetized Guinea Pigs: Comparison With Hydroxyzine

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Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

Kreifels, P., Bódi, I., Hornyik, T., Franke, G., Perez‐Feliz, S., Lewetag, R. D., Moss, R., Castiglione, A., Ziupa, D., Zehender, M., et al. (2022) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2022.101001 · Cited by 4 · see citing works

Pharmacometrics in Cardiovascular Safety

PARKINSON, J. R., Chain, A. S. Y., van der Graaf, P. H., & Visser, S. A. G. (2014) · AAPS advances in the pharmaceutical sciences series · doi:10.1007/978-1-4939-1304-6_7 · Cited by 4 · see citing works

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

Sato, D., Santini, L., Coppini, R., & Grandi, E. (2026) · The Journal of Physiology · doi:10.1113/jp291001 · Cited by 3 · see citing works

Dynamical instability is a major cause of cardiac action potential variability

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Longitudinal changes in intracardiac repolarization lability in patients with implantable cardioverter-defibrillator

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Do women have less repolarization reserve compared to men?

Sprenkeler, D. J., Rivaud, M. R., & Vos, M. A. (2016) · Heart Rhythm · doi:10.1016/j.hrthm.2016.10.009 · Cited by 3 · see citing works

Application of novel QT interval correction and QT/RR assessment models to ECG 24-hour recordings in cardiac patients; pp. 107–120

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Electrocardiographic measures of repolarization heterogeneity are not predictive for Torsades de Pointes among undifferentiated patients with prolonged QTc: A case control study

Marill, K. A., Lopez, S. N., Hark, D., Spahr, J., Muthal, K., Xue, J. Q., Rowlandson, G. I., & Liu, S. W. (2022) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15735 · Cited by 2 · see citing works

The Year of 2008 in Electrocardiology

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Drug-induced Torsades de pointes: Insights from a canine model of chronic atrioventricular block

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Non-Invasive Electrophysiological Markers Associated With Long QT Syndrome

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Drug-Induced QT Prolongation

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Computational analysis of β-adrenergic stimulation and its effects on cardiac ventricular electrophysiology

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Repolarization variability — Friend or foe?

Bergfeldt, L. (2016) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2016.01.006 · Cited by 1 · see citing works

The thorough QT study: let's be precise.

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Group psychotherapy with high grade imbeciles and low grade morons.

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P5-30

Hinterseer, M., Beckmann, B.-M., Thomsen, M. B., Pfeufer, A., Perz, S., Wichmann, H. ‐., Steinbeck, G., Vos, M. A., & Kääb, S. (2006) · Heart Rhythm · doi:10.1016/j.hrthm.2006.02.808 · Cited by 2 · see citing works

Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit

Jacobson, I., Carlsson, L. G., & Duker, G. (2010) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2010.04.010 · Cited by 57 · see citing works

Arrhythmia/electrophysiology

Hinterseer, M., Wacker, A., Perz, S., Sauter, W., Illig, T., Schmitt, C., Wichmann, H. ‐., Steinbeck, G., & Meitinger, T. (2015)

Variability of the QT measurement in healthy men, with implications for selection of an abnormal QT value to predict drug toxicity and proarrhythmia

Morganroth, J., Brozovich, F. V., McDonald, J. T., & Jacobs, R. A. (1991) · The American Journal of Cardiology · doi:10.1016/0002-9149(91)90541-r · Cited by 183 · see citing works

P1-22

McCray, R., Ritchie, M. D., Roden, D. M., & Darbar, D. (2006) · Heart Rhythm · doi:10.1016/j.hrthm.2006.02.345 · Cited by 4 · see citing works