The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Interactions of the heart and the liver
Open accessAbstract
There is a mutual interaction between the function of the heart and the liver and a broad spectrum of acute and chronic entities that affect both the heart and the liver. These can be classified into heart diseases affecting the liver, liver diseases affecting the heart, and conditions affecting the heart and the liver at the same time. In chronic and acute cardiac hepatopathy, owing to cardiac failure, a combination of reduced arterial perfusion and passive congestion leads to cardiac cirrhosis and cardiogenic hypoxic hepatitis. These conditions may impair the liver function and treatment should be directed towards the primary heart disease and seek to secure perfusion of vital organs. In patients with advanced cirrhosis, physical and/or pharmacological stress may reveal a reduced cardiac performance with systolic and diastolic dysfunction and electrophysical abnormalities termed cirrhotic cardiomyopathy. Electrophysiological abnormalities include prolonged QT interval, chronotropic incompetance, and electromechanical uncoupling. No specific therapy can be recommended, but it should be supportive and directed against the heart failure. Numerous conditions affect both the heart and the liver such as infections, inflammatory and systemic diseases, and chronic alcoholism. The risk and prevalence of coronary artery disease are increasing in cirrhotic patients and since the perioperative mortality is high, a careful cardiac evaluation of such patients is required prior to orthotopic liver transplantation.
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Cites
A Model to Predict Survival in Patients With End–Stage Liver Disease
Kamath, P. S., Wiesner, R. H., Malinchoc, M., Kremers, W., Therneau, T. M., Kosberg, C. L., D'Amico, G., Dickson, R. E., & Kim, R. W. (2001) · Hepatology · doi:10.1053/jhep.2001.22172 · Cited by 4,975
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
Targher, G., Day, C. P., & Bonora, E. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0912063 · Cited by 1,907
(2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.05.004 · Cited by 1,725
Long-Term Survival, Modes of Death, and Predictors of Mortality in Patients With Fontan Surgery
Khairy, P., Fernandes, S. M., Mayer, J. E., Triedman, J. K., Walsh, E. P., Lock, J. E., & Landzberg, M. J. (2008) · Circulation · doi:10.1161/circulationaha.107.738559 · Cited by 1,023
EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease
European Association for the Study of the Liver (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.04.004 · Cited by 720
Circulatory function and hepatorenal syndrome in cirrhosis†
Ruiz‐del‐Arbol, L., Monescillo, A., Arocena, C., Valer, P., Ginès, P., Moreira, V., María Milicua, J., Jiménez, W., & Arroyo, V. (2005) · Hepatology · doi:10.1002/hep.20766 · Cited by 592
THE CARDIAC OUTPUT AT REST IN LAENNEC'S CIRRHOSIS 1
Kowalski, H. J., & Abelmann, W. H. (1953) · Journal of Clinical Investigation · doi:10.1172/jci102813 · Cited by 586
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Cited by
Cherry, S. R., Jones, T., Karp, J. S., Qi, J., Moses, W. W., & Badawi, R. D. (2018) · Journal of Nuclear Medicine · doi:10.2967/jnumed.116.184028 · Cited by 763
Bernardi, M., Moreau, R., Angeli, P., Schnabl, B., & Arroyo, V. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.07.004 · Cited by 632
Self-citationArrigo, M., Jessup, M., Mullens, W., Reza, N., Shah, A. M., Sliwa, K., & Mebazaa, A. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0151-7 · Cited by 574
Heart Failure and Liver Disease
Xanthopoulos, A., Starling, R. C., Kitai, T., & Triposkiadis, F. (2019) · JACC: Heart Failure · doi:10.1016/j.jchf.2018.10.007 · Cited by 341
Xie, W., Gan, J., Zhou, X., Tian, H., Pan, X., Liu, W., Li, X., Du, J., Xu, A., Zheng, M., et al. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.04.020 · Cited by 55
Metadata
- Authors
- Møller, S., & Bernardi, M.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-07-12
- Volume
- 34
- Issue
- 36
- Pages
- 2804-2811
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2131348155
- Cited by
- 490
- References
- 94
- FWCI
- 12.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
