The DOI matches its Crossref record; 134 of the 134 references it cites were found in a registry or an index.
Inflammation as a Therapeutic Target in Heart Failure? A Scientific Statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
Open accessAbstract
The increasing prevalence of heart failure poses enormous challenges for health care systems worldwide. Despite effective medical interventions that target neurohumoral activation, mortality and morbidity remain substantial. Evidence for inflammatory activation as an important pathway in disease progression in chronic heart failure has emerged in the last two decades. However, clinical trials of ‘anti-inflammatory’ therapies (such as anti-tumor necrosis factor-α approaches) have to date failed to show benefit in heart failure patients. The Heart Failure Association of the European Society of Cardiology recently organized an expert workshop to address the issue of inflammation in heart failure from a basic science, translational and clinical perspective, and to assess whether specific inflammatory pathways may yet serve as novel therapeutic targets for this condition. This consensus document represents the outcome of the workshop and defines key research questions that still need to be addressed as well as considering the requirements for future clinical trials in this area.
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Cites
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Immunosuppressive effects of apoptotic cells
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Inflammatory Cytokines and Postmyocardial Infarction Remodeling
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Cited by
Schultheiss, H.-P., Fairweather, D., Caforio, A. L. P., Escher, F., Hershberger, R. E., Lipshultz, S. E., Liu, P. P., Matsumori, A., Mazzanti, A., McMurray, J., et al. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0084-1 · Cited by 720
Self-citationWestermann, D., Lindner, D., Kasner, M., Zietsch, C., Savvatis, K., Escher, F., von Schlippenbach, J., Skurk, C., Steendijk, P., Riad, A., et al. (2011) · Circulation Heart Failure · doi:10.1161/circheartfailure.109.931451 · Cited by 644
Self-citationRonco, C., Cicoira, M., & McCullough, P. A. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.01.077 · Cited by 422
The vulnerable phase after hospitalization for heart failure
Greene, S. J., Fonarow, G. C., Vaduganathan, M., Khan, S. S., Butler, J., & Gheorghiade, M. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.14 · Cited by 406
Suthahar, N., Meijers, W. C., Silljé, H. H. W., & de Boer, R. A. (2017) · Current Heart Failure Reports · doi:10.1007/s11897-017-0343-y · Cited by 307
Metadata
- Authors
- Heymans, S., Hirsch, E., Anker, S. D., Aukrust, P., Balligand, J.-L., Cohen-Tervaert, J. W., Drexler, H., Filippatos, G., Felix, S. B., Gullestad, L., Hilfiker-Kleiner, D., Janssens, S., Latini, R., Neubauer, G., Paulus, W. J., Pieske, B., Ponikowski, P., Schroen, B., Schultheiss, H.-P., Tschöpe, C., van Bilsen, M., Zannad, F., McMurray, J., & Shah, A. M.
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-01-28
- Volume
- 11
- Issue
- 2
- Pages
- 119-129
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W2108866738
- Cited by
- 323
- References
- 134
- FWCI
- 17.79
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Inflammation as a Therapeutic Target in Heart Failure? A Scientific Statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. https://app.cochat.ai/papers/10.1093/eurjhf/hfn043
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- Heymans, S., Hirsch, E., Anker, S. D., Aukrust, P., Balligand, J.-L., Cohen-Tervaert, J. W., Drexler, H., Filippatos, G., Felix, S. B., Gullestad, L., Hilfiker-Kleiner, D., Janssens, S., Latini, R., Neubauer, G., Paulus, W. J., Pieske, B., Ponikowski, P., Schroen, B., Schultheiss, H.-P., . . . Shah, A. M. (2009). Inflammation as a Therapeutic Target in Heart Failure? A Scientific Statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure. https://doi.org/10.1093/eurjhf/hfn043
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
