The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease: A Scientific Statement From the American Heart Association, the American College of Cardiology, and the European Society of Cardiology
Abstract
The role of endomyocardial biopsy (EMB) in the diagnosis and treatment of adult and pediatric cardiovascular disease remains controversial, and the practice varies widely even among cardiovascular centers of excellence. A need for EMB exists because specific myocardial disorders that have unique prognoses and treatment are seldom diagnosed by noninvasive testing.1 Informed clinical decision making that weighs the risks of EMB against the incremental diagnostic, prognostic, and therapeutic value of the procedure is especially challenging for nonspecialists because the relevant published literature is usually cited according to specific cardiac diseases, which are only diagnosed after EMB
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EMB remains the gold standard for diagnosing acute myocarditis.
“EMB remains the gold standard for diagnosing acute myocarditis”
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- Authors
- Cooper, L. T., Baughman, K. L., Feldman, A. M., Frustaci, A., Jessup, M., Kuhl, U., Levine, G. N., Narula, J., Starling, R. C., Towbin, J., & Virmani, R.
- Affiliations
- Mayo Clinic (US)
- ORCID
- Venue
- Circulation
- Published
- 2007-11-06
- Volume
- 116
- Issue
- 19
- Pages
- 2216-2233
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2163715968
- Cited by
- 1,030
- References
- 0
- Citations by year
- 2026: 31 · 2025: 38 · 2024: 40 · 2023: 40 · 2022: 56 · 2021: 45 · 2020: 59 · 2019: 45 · 2018: 42 · 2017: 48 · 2016: 74 · 2015: 80 · 2014: 71 · 2013: 81 · 2012: 76
- FWCI
- 32.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R56HL056267)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiomyopathy and Myosin Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Keywords
- endomyocardial biopsy, myocardial disease diagnosis, cardiovascular care, pediatric cardiovascular disease, diagnostic yield, risk-benefit assessment, clinical decision-making
- MeSH terms
- Biopsy, Cardiology, Europe, Heart Diseases, Humans, Societies, Medical, United States
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