Cited by 270Atrial Fibrillation Management and OutcomesCardiac electrophysiology and arrhythmiasCardiac Arrhythmias and Treatments

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Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals

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Mont, Lluís, Tamborero, David, Elosua, Roberto, Molina, Irma, Coll-Vinent, Blanca, Sitges, Marta, Vidal, Bárbara, Scalise, Andrea, Tejeira, Alejandro, Berruezo, Antonio, Brugada, Josep·2008·EP Europace

DOI 10.1093/europace/eum263

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Abstract

AIMS: The aetiology of atrial fibrillation (AF) remains unknown in some patients. The aim of the study was to identify new risk factors for developing lone AF (LAF). METHODS AND RESULTS: A series of 107 consecutive patients younger than 65, seen in the emergency room for an episode of LAF of <48 h duration were included in the study. A group of 107 healthy volunteers matched for age and sex were recruited as controls. All subjects answered a validated questionnaire concerning leisure and occupational activities performed throughout their lifetimes to estimate accumulated hours of physical effort, classified in four levels of intensity. Demographic and echocardiographic measurements were also recorded. There were 69% of males and mean age was 48 +/- 11 years. AF was paroxysmal in 57% and persistent in the remaining 43%. Patients with AF performed more hours of both moderate and heavy intensity physical activity. They also were taller, and had a larger left atria, ventricle, and body surface area. At the multivariable analysis, only moderate and heavy physical activity, height, and anteroposterior atrial diameter were independently associated with LAF. CONCLUSIONS: Accumulated lifetime physical activity, height, and left atrial size are risk factors for LAF in healthy middle-aged individuals.

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Authors: Mont, L., Tamborero, D., Elosua, R., Molina, I., Coll-Vinent, B., Sitges, M., Vidal, B., Scalise, A., Tejeira, A., Berruezo, A., & Brugada, J.
Affiliations: Hospital Clínic de Barcelona (ES)
ORCID: Tamborero, David
Sitges, Marta
Vidal, Bárbara
Scalise, Andrea
Berruezo, Antonio
Venue: EP Europace
Publisher: Oxford University Press (OUP)
Published: 2008-01
Volume: 10
Issue: 1
Pages: 15-20
ISSN: 1099-5129 (ISSN-L)
1532-2092
DOI: 10.1093/europace/eum263
OpenAlex: W2166330383
Cited by: 270
References: 38
Citations by year: 2026: 4 · 2025: 5 · 2024: 9 · 2023: 11 · 2022: 6 · 2021: 20 · 2020: 16 · 2019: 15 · 2018: 22 · 2017: 11 · 2016: 22 · 2015: 23 · 2014: 18 · 2013: 24 · 2012: 20
FWCI: 10.23
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: other-oa
Locations: EP Europace (publishedVersion, other-oa)
PubMed (publishedVersion)
Funders: Sociedad Española de Cardiología
Universitat de Barcelona
Universitat Autònoma de Barcelona
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords: lone atrial fibrillation, physical activity, lifelong physical activity, height, left atrial size, left atrial diameter, risk factors, middle-aged adults, paroxysmal atrial fibrillation, persistent atrial fibrillation, body surface area, atrial volume
MeSH terms: Adult, Atrial Fibrillation, Body Height, Female, Heart Atria, Humans, Male, Middle Aged, Motor Activity, Predictive Value of Tests, Prospective Studies, Risk Factors, Multivariate Analysis, Case-Control Studies

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Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals

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