The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals
Open accessAbstract
AIMS: The aetiology of atrial fibrillation (AF) remains unknown in some patients. The aim of the study was to identify new risk factors for developing lone AF (LAF). METHODS AND RESULTS: A series of 107 consecutive patients younger than 65, seen in the emergency room for an episode of LAF of <48 h duration were included in the study. A group of 107 healthy volunteers matched for age and sex were recruited as controls. All subjects answered a validated questionnaire concerning leisure and occupational activities performed throughout their lifetimes to estimate accumulated hours of physical effort, classified in four levels of intensity. Demographic and echocardiographic measurements were also recorded. There were 69% of males and mean age was 48 +/- 11 years. AF was paroxysmal in 57% and persistent in the remaining 43%. Patients with AF performed more hours of both moderate and heavy intensity physical activity. They also were taller, and had a larger left atria, ventricle, and body surface area. At the multivariable analysis, only moderate and heavy physical activity, height, and anteroposterior atrial diameter were independently associated with LAF. CONCLUSIONS: Accumulated lifetime physical activity, height, and left atrial size are risk factors for LAF in healthy middle-aged individuals.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source doesn’t support the claim as written.
In the citing paper
“Regular exercise of either low or moderate intensity seems serve as a preventive strategy for cardiovascular disease and AF, while higher-intensity endurance exercise may lead to AF [6,7,8,12,13,14,15,16,17,18,19,20,21].”
From Atrial Fibrillation in Elite Athletes: A Comprehensive Review of the Literature (2024) · cites this paper as [7]
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Many retrospective observational studies and meta-analyses have estimated a 2 to 10 times higher frequency of AF in high-intensity endurance athletes compared to individuals who do not exercise [6,7,8,12,13,14,15,16,17].”
From Atrial Fibrillation in Elite Athletes: A Comprehensive Review of the Literature (2024) · cites this paper as [7]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“AF in athletes is considered to be vagal-mediated [7].”
From Atrial Fibrillation in Elite Athletes: A Comprehensive Review of the Literature (2024) · cites this paper as [7]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography
Schiller, N. B., Shah, P. M., Crawford, M., DeMaria, A. N., Devereux, R. B., Feigenbaum, H., Gutgesell, H. P., Reichek, N., Sahn, D. J., Schnittger, I., et al. (1989) · Journal of the American Society of Echocardiography · doi:10.1016/s0894-7317(89)80014-8 · Cited by 8,110
Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins.
Haïssaguerre, M., Jaïs, P., Shah, D. C., Takahashi, A., Hocini, M., Quiniou, G., Garrigue, S., Mouroux, A. L., Métayer, P. L., & Clémenty, J. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809033391003 · Cited by 8,040
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
Nagueh, S. F., Middleton, K. J., Kopelen, H. A., Zoghbi, W. A., & Quiñones, M. A. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00344-6 · Cited by 3,024
Ommen, S. R., Nishimura, R. A., Appleton, C. P., Miller, F. A., Oh, J. K., Redfield, M. M., & Tajik, A. J. (2000) · Circulation · doi:10.1161/01.cir.102.15.1788 · Cited by 2,790
Miyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., Seward, J. B., & Tsang, T. S. M. (2006) · Circulation · doi:10.1161/circulationaha.105.595140 · Cited by 2,564
Kannel, W. B., Wolf, P. A., Benjamin, E. J., & Levy, D. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00583-9 · Cited by 2,033
Obesity and the risk of new-onset atrial fibrillation
Wang, T. J. (2004) · JAMA · doi:10.1001/jama.292.20.2471 · Cited by 1,427
Fuster, V., Rydén, L., Cannom, D. S., Crijns, H. J. G. M., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Heuzey, J. L., Kay, G. N., Lowe, J. E., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.07.009 · Cited by 1,161
New Doppler echocardiographic applications for the study of diastolic function
Garcia, M. J., Thomas, J. D., & Klein, A. L. (1998) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(98)00345-3 · Cited by 998
Impact of Atrial Fibrillation on Mortality, Stroke, and Medical Costs
Wolf, P. A., Mitchell, J. B., Baker, C. S., Kannel, W. B., & D’Agostino, R. B. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.3.229 · Cited by 683
Left atrial volume as an index ofleft atrial size: a population-based study
Pritchett, A. M., Jacobsen, S. J., Mahoney, D. W., Rodeheffer, R. J., Bailey, K. R., & Redfield, M. M. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02981-9 · Cited by 583
Characterization of Different Subsets of Atrial Fibrillation in General Practice in France
Lévy, S., Maarek, M., Coumel, P., Guize, L., Lekieffre, J., Medvedowsky, J. L., & Sebaoun, A. (1999) · Circulation · doi:10.1161/01.cir.99.23.3028 · Cited by 580
Best method in clinical practice and in research studies to determine left atrial size
Lester, S. J., Ryan, E. W., Schiller, N. B., & Foster, E. (1999) · The American Journal of Cardiology · doi:10.1016/s0002-9149(99)00446-4 · Cited by 532
Oki, T., Tabata, T., Yamada, H., Wakatsuki, T., Shinohara, H., Nishikado, A., Íuchi, A., Fukuda, N., & Ito, S. (1997) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)00015-5 · Cited by 485
Prevalence and Clinical Significance of Left Atrial Remodeling in Competitive Athletes
Pelliccia, A., Maron, B. J., Di Paolo, F. M., Biffi, A., Quattrini, F. M., Pisicchio, C., Roselli, A., Caselli, S., & Culasso, F. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.04.052 · Cited by 443
Heidbüchel, H. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)00282-3 · Cited by 395
[Guidelines for the management of patients with atrial fibrillation. Executive summary].
Fuster, V., Rydén, L., Cannom, D. S., Crijns, H. J. G. M., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Heuzey, J. L., Kay, G. N., Lowe, J. E., et al. (2006) · PubMed · Cited by 356
Long-lasting sport practice and lone atrial fibrillation
Mont, L. (2002) · European Heart Journal · doi:10.1053/euhj.2001.2802 · Cited by 331
Self-citationLone atrial fibrillation in vigorously exercising middle aged men: case-control study
Karjalainen, J., Kujala, U. M., Kaprio, J., Sarna, S., & Viitasalo, M. (1998) · BMJ · doi:10.1136/bmj.316.7147.1784 · Cited by 326
The Lifetime Total Physical Activity Questionnaire: development and reliability
Friedenreich, C. M., Courneya, K. S., & Bryant, H. E. (1998) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199802000-00015 · Cited by 287
Risk of New-Onset Atrial Fibrillation in Relation to Body Mass Index
Dublin, S. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.21.2322 · Cited by 268
Sport practice and the risk of lone atrial fibrillation: a case-control study
Elosua, R., Arquer, A., Mont, L., Sambola, A., Molina, L., García-Morán, E., Brugada, J., & Marrugat, J. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2005.05.020 · Cited by 250
Self-citationAtrial fibrillation : mechanisms and management
Falk, R. H., & Podrid, P. J. (1992) · Lippincott-Raven eBooks · Cited by 237
Persistent and reversible cardiac dysfunction among amateur marathon runners
Neilan, T. G., Yoerger, D. M., Douglas, P. S., Marshall, J. E., Halpern, E. F., Lawlor, D., Picard, M. H., & Wood, M. J. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehi813 · Cited by 206
Atrial Volume in a Normal Adult Population by Two-dimensional Echocardiography
Wang, Y., Gutman, J. M., Heilbron, D. C., WAHR, D. W., & Schiller, N. B. (1984) · CHEST Journal · doi:10.1378/chest.86.4.595 · Cited by 189
Endurance sports is a risk factor for atrial fibrillation after ablation for atrial flutter
Heidbüchel, H., Anné, W., Willems, R., Adriaenssens, B., Van de Werf, F., & Ector, H. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2005.02.043 · Cited by 180
Ommen, S. R., & Nishimura, R. A. (2003) · Heart · doi:10.1136/heart.89.suppl_3.iii18 · Cited by 172
Paroxysmal atrial fibrillation in male endurance athletes. A 9-year follow up
Hoogsteen, J. (2004) · Europace · doi:10.1016/j.eupc.2004.01.004 · Cited by 134
Swanson, D. R. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2006.01.006 · Cited by 81
Use of intravenous flecainide in horses with naturally‐occurring atrial fibrillation
van Loon, G., BLISSITT, K. J., Keen, J., & Young, L. E. (2004) · Equine Veterinary Journal · doi:10.2746/0425164044864516 · Cited by 57
Hanna, I. R., Heeke, B., Bush, H., Brosius, L., King-Hageman, D., Beshai, J. F., & Langberg, J. J. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.11.068 · Cited by 56
Atrial Fibrillation: Mechanisms and Management
Liu, T., Tse, G., Yu, L., Korantzopoulos, P. G., & Letsas, Κ. P. (2019) · Cardiology Research and Practice · doi:10.1155/2019/8909371 · Cited by 43
Phang, R. S., Isserman, S., Karia, D. H., Pandian, N. G., Homoud, M. K., Link, M. S., Estes, N. A. M., & Wang, P. J. (2004) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.05.009 · Cited by 39
Experimental models of atrial fibrillation/flutter
Friedrichs, G. S. (2000) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/s1056-8719(00)00098-8 · Cited by 15
Perfil clínico de la fibrilación auricular paroxística idiopática (registro FAP)
Planas, F., Antúnez, F., Poblet, T., Pujol, M., Romero, C. R., Sadurní, J. R., Vázquez, G., Moya‐Mitjans, À., & López, F. N. (2001) · Revista Española de Cardiología · doi:10.1016/s0300-8932(01)76409-3 · Cited by 15
The Epidemiology of Atrial Fibrillation
Wang, T. J., & Benjamin, E. J. (2004) · CRC Press eBooks · doi:10.3109/9780203996935-7 · Cited by 11
Atrial fibrillation in athletes.
Farrar, M. W., Bogart, D. B., Chapman, S. S., & Rigden, L. B. (2006) · PubMed · Cited by 8
Research works printed but not linked: 1
- Farrar, 2006, Atrial fibrillation in atheletes, Mo Med, 103, 297
Cited by
Sorted by citations
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castella, M., Dan, G.-A., Dilaveris, P., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 10,550
Self-citationCalkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Europace · doi:10.1093/europace/eus027 · Cited by 2,722
Self-citationCalkins, H. G., Kück, K., Cappato, R., Brugada, J., Camm, A. J., Chen, S., Crijns, H. J. G. M., Damiano, R. J., Davies, D. W., Dimarco, J., et al. (2012) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-012-9672-7 · Cited by 1,685
Self-citationCalkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2011.12.016 · Cited by 1,456
Self-citationSchnabel, R. B., SULLIVAN, L. M., Levy, D. A., Pencina, M. J., Massaro, J. M., D’Agostino, R. B., Newton‐Cheh, C., Yamamoto, J. F., Magnani, J. W., Tadros, T. M., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60443-8 · Cited by 1,038
Metadata
- Authors
- Mont, L., Tamborero, D., Elosua, R., Molina, I., Coll-Vinent, B., Sitges, M., Vidal, B., Scalise, A., Tejeira, A., Berruezo, A., & Brugada, J.
- Affiliations
- Hospital Clínic de Barcelona (ES)
- Venue
- EP Europace
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-01
- Volume
- 10
- Issue
- 1
- Pages
- 15-20
- ISSN
- 1099-5129 (ISSN-L)
- 1532-2092
- OpenAlex
- W2166330383
- Cited by
- 270
- References
- 38
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 9 · 2023: 11 · 2022: 6 · 2021: 20 · 2020: 16 · 2019: 15 · 2018: 22 · 2017: 11 · 2016: 22 · 2015: 23 · 2014: 18 · 2013: 24 · 2012: 20
- FWCI
- 10.23
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- other-oa
- Locations
- EP Europace (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Funders
- Sociedad Española de Cardiología
- Universitat de Barcelona
- Universitat Autònoma de Barcelona
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Keywords
- lone atrial fibrillation, physical activity, lifelong physical activity, height, left atrial size, left atrial diameter, risk factors, middle-aged adults, paroxysmal atrial fibrillation, persistent atrial fibrillation, body surface area, atrial volume
- MeSH terms
- Adult, Atrial Fibrillation, Body Height, Female, Heart Atria, Humans, Male, Middle Aged, Motor Activity, Predictive Value of Tests, Prospective Studies, Risk Factors, Multivariate Analysis, Case-Control Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
