The primary biological network of Bifidobacterium in the gut
Abstract
Bacterial interactions in the biological network affect the growth of Bifidobacterium. In the present study, five habitats were constructed by changing animals, their health statuses and their diets. In each of these habitats, different networks of Bifidobacterium were outlined through correlation analysis of the 50 most dominant microbes. Thirty-eight bacterial genera directly correlated with the growth of Bifidobacterium, including 23 genera with a positive correlation and 15 genera with a negative correlation. This study presented, to our knowledge, a new biological network of rodent gut Bifidobacterium under various representative habitats. This study shows an in vivo network of Bifidobacterium, thereby contributing to constructing an in vitro network of Bifidobacterium for further studies.
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The bacterial profile in ARFID suggests a dysbiotic state that may contribute to ARFID pathogenesis.
“Given Bifidobacterium’s established role in immune regulation, inflammation control, and potential anti-aging effects [122], this bacterial profile suggests a dysbiotic state that may contribute to ARFID pathogenesis.”
From Unraveling the Connections: Eating Issues, Microbiome, and Gastrointestinal Symptoms in Autism Spectrum Disorder (2025) · cites this paper as [122]
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- Authors
- Luo, J., Li, Y., Xie, J., Gao, L., Liu, L., Ou, S., Chen, L., & Peng, X.
- Affiliations
- Jinan University (CN)
- Corresponding author
- Peng, Xichun
- Venue
- FEMS Microbiology Letters
- Publisher
- Oxford University Press (OUP)
- Published
- 2018-03-13
- Volume
- 365
- Issue
- 8
- ISSN
- 0378-1097 (ISSN-L)
- 1574-6968
- OpenAlex
- W2793173966
- Cited by
- 36
- References
- 38
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 5 · 2023: 12 · 2022: 7 · 2021: 3 · 2020: 2
- FWCI
- 0.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- FEMS Microbiology Letters (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Funds (31601441, 31471589)
- Natural Science Funds (2016A030313111)
- Science and Technology Program (201510010115)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- Bifidobacterium, gut microbiota, microbial co-occurrence networks, bacterial interactions, diet effects
- MeSH terms
- Gastrointestinal Microbiome, Animals, Animal Feed, Bacteria, Bifidobacterium, Humans, Ecosystem, Gastrointestinal Tract, Mice, Rats
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