In vitro evaluation of the impact of human background microbiota on the response to Bifidobacterium strains and fructo-oligosaccharides
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The microbial colonisation of the infant gut begins immediately after birth and is essential for the development of the intestine, the immune system and later well-being. Important differences have been reported in the characteristics of such microbiota in different infant population groups. In the present study, we employed an in vitro faecal batch culture model using faeces from different human population groups (adults and full-term breast-fed, full-term formula-fed and preterm infants) to determine the influence that the addition of four bifidobacterial strains and fructo-oligosaccharides (FOS) exerts on the profile of SCFA measured by GC as well as on the levels of some relevant intestinal microbial groups by quantitative PCR during incubation. Differences were found in the levels of SCFA and intestinal microbial groups in the faecal cultures depending on the human group origin of the faecal samples (P< 0·05), this being a predominant factor, compared with bifidobacteria or FOS added, in determining microbiota dynamics. These results exhibit the importance of the initial characteristics of the basal intestinal microbiota in the effect exerted by bifidobacteria or FOS that are added and highlight the need to design probiotics targeting specific human population groups.
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Individuals with different gut microbiota composition appear to respond differently to Bifidobacterium supplementation.
“Further evidence of the existence of a bifidobacterial-gut microbiota cross talk has been provided by the fact that individuals with different gut microbiota composition appear to respond differently to Bifidobacterium supplementation (73).”
From Bifidobacteria and Their Health-Promoting Effects (2017) · cites this paper as [73]
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Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial
Kalliomäki, M. A., Salminen, S., Arvilommi, H. S., Kero, P. O., Koskinen, P. J., & Isolauri, E. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04259-8 · Cited by 2,434 · see citing works
Factors influencing the composition of the intestinal microbiota in early infancy
Penders, J., Thijs, C., Vink, C., Stelma, F. F., Snijders, B., Kummeling, I., van den Brandt, P. A., & Stobberingh, E. E. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2824 · Cited by 2,232 · see citing works
Harmsen, H. J. M., Wildeboer-Veloo, A. C. M., Raangs, G. C., Wagendorp, A. A., Klijn, N., BINDELS, J. G., & Welling, G. W. (2000) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200001000-00019 · Cited by 1,326 · see citing works
Bezirtzoglou, E., Tsiotsias, A., & Welling, G. W. (2011) · Anaerobe · doi:10.1016/j.anaerobe.2011.03.009 · Cited by 453 · see citing works
Establishment and development of intestinal microbiota in preterm neonates
Arboleya, S., Binetti, A. G., Salazar, N., Fernández, N., Sánchez, G. S., Hernández‐Barranco, A. M., Margollés, A., Reyes‐Gavilán, C. G. D. L., & Gueimonde, M. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01261.x · Cited by 439 · see citing works
Self-citationYoung, J. P. W., Downer, H. L., & Eardly, B. D. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.7.2271-2277.1991 · Cited by 399 · see citing works
Kopp, M., Hennemuth, I., Heinzmann, A., & Urbanek, R. (2008) · PEDIATRICS · doi:10.1542/peds.2007-1492 · Cited by 386 · see citing works
van Baarlen, P., Troost, F. J., van Kraaij, C., Hooiveld, G. J. E. J., Boekschoten, M. V., Brummer, R. J., & Kleerebezem, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000079107 · Cited by 336 · see citing works
Recommendations for Probiotic Use—2011 Update
Floch, M. H., Walker, W. A., Madsen, K. L., Sanders, M. E., Macfarlane, G. T., Flint, H. J., Dieleman, L. A., Ringel, Y., Guandalini, S., Kelly, C. P., et al. (2011) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e318230928b · Cited by 207 · see citing works
Conditions of Bifidobacterial Colonization in Preterm Infants: A Prospective Analysis
Butel, M., Suau, A., Campeotto, F., Magne, F., Aires, J., Ferraris, L., Kalach, N., Leroux, B., & Dupont, C. M. (2007) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3180406b20 · Cited by 170 · see citing works
Salazar, N., Prieto, A., Leal, J. A., Mayo, B., Bada-Gancedo, J. C., de los Reyes-Gavilán, C. G., & Ruas-Madiedo, P. (2009) · Journal of Dairy Science · doi:10.3168/jds.2009-2126 · Cited by 143 · see citing works
Self-citationArboleya, S., Ruas-Madiedo, P., Margolles, A., Solís, G., Salminen, S., de los Reyes-Gavilán, C. G., & Gueimonde, M. (2011) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.10.036 · Cited by 139 · see citing works
Manufacturing process influences properties of probiotic bacteria
Grześkowiak, Ł., Isolauri, E., Salminen, S., & Gueimonde, M. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510004496 · Cited by 120 · see citing works
Self-citationGut microbiota and probiotics in maternal and infant health
Sanz, Y. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.001172 · Cited by 111 · see citing works
DE PRETER, V., VANHOUTTE, T., HUYS, G., SWINGS, J., RUTGEERTS, P., & VERBEKE, K. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03588.x · Cited by 104 · see citing works
Grześkowiak, Ł., Grönlund, M., Beckmann, C., Salminen, S., Berg, A. V., & Isolauri, E. (2011) · Anaerobe · doi:10.1016/j.anaerobe.2011.09.006 · Cited by 85 · see citing works
Facultative to strict anaerobes ratio in the preterm infant microbiota: A target for intervention?
Arboleya, S., Solís, G., Fernández, N., de los Reyes-Gavilán, C. G., & Gueimonde, M. (2012) · Gut Microbes · doi:10.4161/gmic.21942 · Cited by 74 · see citing works
Self-citationDiet creates metabolic niches in the "immature gut" that shape microbial communities.
Poroyko, V. A., Morowitz, M. J., Bell, T., ULANOV, A. V., Wang, M., Donovan, S. M., Bao, N., Gu, S., Hong, L., Alverdy, J. C., et al. (2011) · PubMed · doi:10.1590/s0212-16112011000600015 · Cited by 65 · see citing works
Cardelle‐Cobas, A., Fernández, M., Salazar, N., Martínez‐Villaluenga, C., Villamiel, M., Ruas‐Madiedo, P., & Reyes‐Gavilán, C. G. D. L. (2009) · Journal of Dairy Research · doi:10.1017/s0022029909004063 · Cited by 59 · see citing works
Self-citationArboleya, S., Salazar, N., Solís, G., Fernández, N., Hernández-Barranco, A. M., Cuesta, I., Gueimonde, M., & de los Reyes-Gavilán, C. G. (2013) · Anaerobe · doi:10.1016/j.anaerobe.2012.11.001 · Cited by 51 · see citing works
Self-citationAmarri, S., Benatti, F., Callegari, M. L., Shahkhalili, Y., Chauffard, F., Rochat, F., Acheson, K. J., Hager, C., Benyacoub, J., Galli, E., et al. (2006) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000221907.14523.6d · Cited by 42 · see citing works
Garrigues, C., Stuer‐Lauridsen, B., & Johansen, E. (2005) · Australian Journal of Dairy Technology · Cited by 40 · see citing works
Development of probiotic products for nutritional requirements of specific human populations
Arboleya, S., González, S., Salazar, N., Ruas‐Madiedo, P., Reyes‐Gavilán, C. G. D. L., & Gueimonde, M. (2012) · Engineering in Life Sciences · doi:10.1002/elsc.201100129 · Cited by 18 · see citing works
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Bifidobacteria and Their Health-Promoting Effects
Hidalgo-Cantabrana, C., Delgado, S., Ruiz, L., Ruas-Madiedo, P., Sánchez, B., & Margolles, A. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.bad-0010-2016 · Cited by 490 · see citing works
The primary biological network of Bifidobacterium in the gut
Luo, J., Li, Y., Xie, J., Gao, L., Liu, L., Ou, S., Chen, L., & Peng, X. (2018) · FEMS Microbiology Letters · doi:10.1093/femsle/fny057 · Cited by 36 · see citing works
- Authors
- Arboleya, S., Salazar, N., Solís, G., Fernández, N., Gueimonde, M., & de los Reyes-Gavilán, C. G.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- Hospital Universitario De Cabueñes (ES)
- Venue
- British Journal of Nutrition
- Publisher
- Cambridge University Press (CUP)
- Published
- 2013-05-31
- Volume
- 110
- Issue
- 11
- Pages
- 2030-2036
- ISSN
- 0007-1145 (ISSN-L)
- 1475-2662
- OpenAlex
- W2156579683
- Cited by
- 25
- References
- 23
- Citations by year
- 2024: 1 · 2022: 2 · 2021: 5 · 2020: 1 · 2019: 2 · 2018: 4 · 2017: 3 · 2016: 4 · 2015: 3
- FWCI
- 2.16
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal Of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by-nc-nd)
- Funders
- European Commission
- Ministerio de Economía y Competitividad (AGL2010-16525)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- human gut microbiome, Bifidobacterium, fructooligosaccharides, short-chain fatty acids, preterm infants, breast-fed infants, formula-fed infants, probiotics, prebiotics
- MeSH terms
- Adult, Bifidobacterium, Breast Feeding, Fatty Acids, Volatile, Feces, Fermentation, Gram-Negative Bacteria, Gram-Positive Bacteria, Humans, Infant, Newborn, Infant, Premature, Intestines, Oligosaccharides, Spain, Species Specificity, Probiotics, Infant Formula, Term Birth, Microbial Interactions, Prebiotics, Molecular Typing, Batch Cell Culture Techniques
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