The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation.

Eissenberg, J C, Morris, G D, Reuter, G, Hartnett, T·1992·Genetics

Cited by (315)

Items 201–300 of 315

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  2. pitkinD, a Novel Gain-of-Function Enhancer of Position-Effect Variegation, Affects Chromatin Regulation During Oogenesis and Early Embryogenesis in Drosophila
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  3. A high proportion of genes involved in position effect variegation also affect chromosome inheritance
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  4. The Impact of Local Genome Sequence on Defining Heterochromatin Domains
    Bayly S. Wheeler, Jared A. Blau, Huntington F. Willard, Kristin C. Scott · 2009 · PLoS Genetics
  5. Mitotic fidelity requires transgenerational action of a testis-restricted HP1
    Mia T Levine, Helen Vander Wende, Harmit Singh Malik · 2015 · eLife
  6. Time out: developmental regulation of heterochromatic silencing in Drosophila
    B. Y. Lu, Joel C. Eissenberg · 1998 · Cellular and Molecular Life Sciences
  7. A novel Fizzy/Cdc20-dependent mechanism suppresses necrosis in neural stem cells
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  8. Interactions Among Dosage-Dependent Trans-Acting Modifiers of Gene Expression and Position-Effect Variegation in Drosophila
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  9. Are postnatal hemangioblasts generated by dedifferentiation from committed hematopoietic stem cells?
    G. Prindull, Eitan Fibach · 2007 · Experimental Hematology
  10. Phase transitions in heterochromatin organization
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  11. A new gene in Drosophila melanogaster, Ravus, the phantom of the modifier of position-effect variegation Su(var)3-7
    Marion Delattre, Anne Spierer, Nicolas Hulo, Pierre Spierer · 2002 · The International Journal of Developmental Biology
  12. Heterochromatin, Position Effects, and the Genetic Dissection of Chromatin
    Joel C. Eissenberg, Lori L. Wallrath · 2003 · Progress in nucleic acid research and molecular biology
  13. Reduced heterochromatin protein 1-beta (HP1beta) expression is correlated with increased invasive activity in human melanoma cells.
    Keisuke Nishimura, YOSHIFUMI S. HIROKAWA, Hitoshi Mizutani, Taizo Shiraishi · 2006 · PubMed
  14. A Balance Between Euchromatic (JIL-1) and Heterochromatic [SU(VAR)2-5 and SU(VAR)3-9] Factors Regulates Position-Effect Variegation inDrosophila
    Chao Wang, Jack R. Girton, Jørgen Johansen, Kristen M. Johansen · 2011 · Genetics
  15. Characterization of the Drosophila Group Ortholog to the Amino-Terminus of the Alpha-Thalassemia and Mental Retardation X-Linked (ATRX) Vertebrate Protein
    Brenda López-Falcón, Silvia Meyer‐Nava, Benjamín Hernández-Rodríguez, Adam A. Campos-Acevedo, Daniel Montero, Enrique Rudiño-Piñera, Martha Vâzquez, Mario Zurita, Viviana Valadéz-Graham · 2014 · PLoS ONE
  16. E3 ubiquitin ligase HECW2 mediates the proteasomal degradation of HP1 isoforms
    Vidhya Krishnamoorthy, Richa Khanna, Veena K. Parnaik · 2018 · Biochemical and Biophysical Research Communications
  17. Fine-Scale Position Effects Shape the Distribution of Inversion Breakpoints in Drosophila melanogaster
    Jakob McBroome, David Liang, Russell B Corbett-Detig · 2020 · Genome Biology and Evolution
  18. Heterochromatin formation in Drosophila requires genome-wide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryogenesis
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  19. TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
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  21. Use of MAR Elements to Increase the Production of Recombinant Proteins
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  22. Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction
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  23. Gene regulation by human orthologs of Drosophila heterochromatin protein 1
    Kyu-Kye Hwang, Howard J. Worman · 2002 · Biochemical and Biophysical Research Communications
  24. S-Phase Favours Notch Cell Responsiveness in the Drosophila Bristle Lineage
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  25. Appearance and heterochromatin localization of HP1α in early mouse embryos depends on cytoplasmic clock and H3S10 phosphorylation
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  26. Carnitine suppression of position-effect variegation in Drosophila melanogaster
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  27. Analysis of Chromatin Structure of Genes Silenced by Heterochromatin in Trans
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  28. Molecular genetics of X-chromosome inactivation
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  29. HP1a-mediated heterochromatin formation inhibits high dietary sugar-induced tumor progression
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  30. P element regulation and X-chromosome subtelomeric heterochromatin in Drosophila melanogaster
    Stéphane Ronsseray, Monique Lehmann, Danielle Nouaud, Dominique Anxolabéhère · 1997 · Contemporary issues in genetics and evolution
  31. Isolation of chromosome-associated proteins from Drosophila melanogaster that bind a human centromeric DNA sequence.
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  32. Transcriptional repression in stochastic gene expression, patterning, and cell fate specification
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  33. Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression
    Wenlong Cheng, Tian Li, Bing Wang, Yongqiang Qi, Wenhua Huang, Hongbo Li, Yongjun Chen · 2016 · Oncotarget
  34. The C‐terminal chromodomain‐like module in the integrase domain is crucial for high transposition efficiency of the retrotransposon MAGGY
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  35. P element regulation and X-chromosome subtelomeric heterochromatin in Drosophila melanogaster
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  36. A Pairing-Looping Model for Position-Effect Variegation in Drosophila
    Steven Henikoff · 1996 · Stadler genetics symposia series
  37. Heterochromatin and Euchromatin
    Joel C. Eissenberg, Sarah C. R. Elgin · 2014 · Encyclopedia of Life Sciences
  38. The winged-helix transcription factor JUMU is a haplo-suppressor/triplo-enhancer of PEV in various tissues but exhibits reverse PEV effects in the brain of Drosophila melanogaster
    Annemarie Hofmann, Madeleine Brünner, Günter Korge · 2009 · Chromosome Research
  39. The Role of Maternal HP1a in Early Drosophila Embryogenesis via Regulation of Maternal Transcript Production
    Ah Rume Park, Na Liu, Nils Neuenkirchen, Qiaozhi Guo, Haifan Lin · 2018 · Genetics
  40. HP1B is a euchromatic Drosophila HP1 homolog with links to metabolism
    Benjamin B. Mills, Andrew D. Thomas, Nicole C. Riddle · 2018 · PLoS ONE
  41. Conserved domains control heterochromatin localization and silencing properties of SU(VAR)3–7
    Yannis Jaquet, Marion Delattre, Juan I. Montoya‐Burgos, Anne Spierer, Pierre Spierer · 2006 · Chromosoma
  42. An acquired state: epigenetic mechanisms in transcription
    Lorraine Pillus · 1992 · Current Opinion in Cell Biology
  43. Epitope analysis of chromo antigen and clinical features in a subset of patients with anti-centromere antibodies
    Yoshinao Muro, Taku Yamada, T Iwai, Kenji Sugimoto · 1996 · Molecular Biology Reports
  44. Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals
    Lisa Baumgartner, Jonathan J. Ipsaro, Ulrich Hohmann, Dominik Handler, Alexander Schleiffer, Peter Duchek, Julius Brennecke · 2024 · eLife
  45. The Growth, Pathogenesis, and Secondary Metabolism of Fusarium verticillioides Are Epigenetically Modulated by Putative Heterochromatin Protein 1 (FvHP1)
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  46. Su(var)2-10 - and Su(var)205 -dependent upregulation of the heterochromatic gene neverland is required for developmental transition in Drosophila
    Yuya Ohhara, Yuki Kato, Takumi Kamiyama, Kimiko Yamakawa‐Kobayashi · 2022 · Genetics
  47. Maintenance of Heterochromatin by the Large Subunit of the CAF-1 Replication-Coupled Histone Chaperone Requires Its Interaction with HP1a Through a Conserved Motif
    Baptiste Roelens, Marie Clémot, Mathieu Leroux‐Coyau, Benjamin Klapholz, Nathalie Dostatni · 2016 · Genetics
  48. In praise of mealybugs
    Vani Brahmachari, Surbhi Kohli, Parul Gulati · 2018 · Journal of Genetics
  49. The zinc-finger proteins WOC and ROW play distinct functions within the HP1c transcription complex
    Gianmarco Di Mauro, Albert Carbonell, Paula Escudero-Ferruz, Fernando Azorı́n · 2020 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  50. Transgenerational effect of drug-mediated inhibition of LSD1 on eye pigment expression in Drosophila
    Sigrid Hoyer‐Fender · 2020 · BMC Ecology
  51. Mitotic misbehavior of aDrosophila melanogastersatellite in ring chromosomes: insights into intragenomic conflict among heterochromatic sequences
    Patrick M. Ferree · 2014 · Fly
  52. HP2-like protein: a new piece of the facultative heterochromatin puzzle
    Silvia Volpi, Silvia Bongiorni, Giorgio Prantera · 2007 · Chromosoma
  53. RNAi in Cultured Drosophila Cells
    Ling-Rong Kao, Timothy L. Megraw · 2004 · Humana Press eBooks
  54. Satellite DNA from the brine shrimp Artemia affects the expression of a flanking gene in yeast
    Domenico Maiorano, R Cece, Gianfranco Badaracco · 1997 · Gene
  55. Heterochromatin: A Critical Part of the Genome
    Lori L. Wallrath, Michael W. Vitalini, Sarah C. R. Elgin · 2013 · Springer eBooks
  56. Regulation of the SUV39H Family Methyltransferases: Insights from Fission Yeast
    Rinko Nakamura, Jun‐ichi Nakayama · 2023 · Biomolecules
  57. Corepressor Proteins and Control of Transcription in Yeast
    James R. Bone, Sharon Y. Roth · 2001 · Current topics in microbiology and immunology
  58. Expanding the HP1a-binding consensus and molecular grammar for heterochromatin assembly
    Serafin U. Colmenares, Shingo Tsukamoto, Collin Hickmann, Lucy D. Brennan, Mohammad Khavani, Mohammad R. K. Mofrad, Gary H. Karpen · 2025 · Nucleic Acids Research
  59. HP1a-mediated heterochromatin formation promotes antimicrobial responses against Pseudomonas aeruginosa infection
    Po-Jen Wu, Shian‐Jang Yan · 2022 · BMC Biology
  60. A rapidly evolving genomic toolkit for Drosophila heterochromatin
    Mia T Levine, Harmit Singh Malik · 2013 · Fly
  61. X-Chromosome Inactivation
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  62. The Function of Like Heterochromatin Protein 1 (LHP1) as an Epigenetic Regulator of Plant Development
    Sivabalan Karthik, Seong Ju Han, Jia Chae, Hye Jeong Kim, Jee Hye Kim, Young‐Soo Chung, Jae Bok Heo · 2024 · Journal of Plant Biology
  63. Heterochromatin protein 1 beta regulates neural and neural crest development by repressing pluripotency‐associated gene pou5f3.2/oct25 in Xenopus
    Chih‐Liang Tien, Saeid Mohammadparast, Chenbei Chang · 2021 · Developmental Dynamics
  64. Telomeric Trans-Silencing: an epigenetic repression combining RNA silencing and heterochromatin formation
    Thibaut Josse, Laure Teysset, Anne‐Laure Todeschini, Clara Sidor, Dominique Anxolabéhère, Stéphane Ronsseray · 2005 · PLoS Genetics
  65. Phosphorylation as a regulatory mechanism of HP1 protein multifunctionality
    James C. Walts, Nicole C. Riddle · 2025 · Chromosoma
  66. Live analysis of position-effect variegation in Drosophila reveals different modes of action for HP1a and Su(var)3-9
    Farah Bughio, Keith A. Maggert · 2022 · Proceedings of the National Academy of Sciences
  67. Heterochromatin-based silencing of a foreign tandem repeat in Drosophila melanogaster shows unusual biochemistry and temperature sensitivity
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  68. X ‐Chromosome Inactivation
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  69. Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals
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  70. Chromosomal Position Effects and Gene Variegation
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  71. Genetic factors controllingwhitegene expression of the transposonAR4-24at a telomere inDrosophila melanogaster
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  73. Transcriptional Coactivator SAYP Can Suppress Transcription in Heterochromatin
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  74. A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene
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  75. Characterization of a new class of transcribed repetitive DNA sequence which also exists as a hybrid with HP1 mRNA; potential for site-specific recombination in drosophila melanogaster
    Vivian K. Ngan, Guido N. Vacano, Ursula Bond, Tharappel C. James · 1995 · Insect Biochemistry and Molecular Biology
  76. Heterochromatin Protein 1 Deleted Chromo Domain Decreases Gene Silencing of Transgene in Mouse
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  77. Genetic and molecular characterization of chromosome three heterochromatin in Drosophila melanogaster
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  78. Epigenetics and targeting mechanisms in Drosophila melanogaster
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  79. Chromo Autoantibodies
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