The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Testing heterozygote excess and deficiency.
Abstract
Currently used tests of Hardy-Weinberg proportions do not take into account the nature of the alternative hypothesis, which is generally a heterozygote deficiency. Different exact tests, appropriate for small sample size and large number of alleles, are proposed in this perspective, and their properties are evaluated by power comparisons. Some tests are found to be close to optimal for the detection of inbreeding or heterozygote excess, one of which is a score test closely related to Robertson and Hill's estimator of the inbreeding coefficient. This test is also easily applied to multiple samples. Such tests are not always the most appropriate if alternative hypotheses differ from those considered here.
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Citations
Cites
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Cited by
Fine‐scaled geographical population structuring in a highly mobile marine species: the Atlantic cod
Knutsen, H., Jorde, P. E., André, C., & Stenseth, N. C. (2003) · Molecular Ecology · doi:10.1046/j.1365-294x.2003.01750.x · Cited by 370
Lu, G., & Bernatchez, L. (1999) · Evolution · doi:10.1111/j.1558-5646.1999.tb05413.x · Cited by 273
van Meurs, J. B. J. (2008) · JAMA · doi:10.1001/jama.299.11.1277 · Cited by 264
Genetic structure of the world’s polar bear populations
Paetkau, D., Amstrup, S. C., Born, E. W., Calvert, W., Derocher, A. E., Garner, G. W., Messier, F., Stirling, I., Taylor, M. K., Wiig, Ø., et al. (1999) · Molecular Ecology · doi:10.1046/j.1365-294x.1999.00733.x · Cited by 262
Population structure of Anopheles gambiae in Africa
Lehmann, T. (2003) · Journal of Heredity · doi:10.1093/jhered/esg024 · Cited by 191
Metadata
- Authors
- Rousset, F., & Raymond, M.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-08-01
- Volume
- 140
- Issue
- 4
- Pages
- 1413-1419
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2110076538
- Cited by
- 770
- References
- 21
- FWCI
- 8.11
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
