Cited by 116Forensic and Genetic ResearchPleistocene-Era Hominins and ArchaeologyGenetic diversity and population structure

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Detecting Ancient Admixture in Humans Using Sequence Polymorphism Data

Wall, Jeffrey D·2000·Genetics

DOI 10.1093/genetics/154.3.1271

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Abstract

A debate of long-standing interest in human evolution centers around whether archaic human populations (such as the Neanderthals) have contributed to the modern gene pool. A model of ancient population structure with recent mixing is introduced, and it is determined how much information (i.e., sequence data from how many unlinked nuclear loci) would be necessary to distinguish between different demographic scenarios. It is found that ~50–100 loci are necessary if plausible parameter estimates are used. There are not enough data available at the present to support either the “single origin” or the “multiregional” model of modern human evolution. However, this information should be available in a few years.

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Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.
Tajima, F. (1989) · Genetics · doi:10.1093/genetics/123.3.585 · Cited by 14,056
The History and Geography of Human Genes
Cavalli-Sforza, L. L., Menozzi, P., & Piazza, A. (2018) · Princeton University Press eBooks · doi:10.2307/j.ctv301gjp · Cited by 3,175
EVOLUTIONARY RELATIONSHIP OF DNA SEQUENCES IN FINITE POPULATIONS
Tajima, F. (1983) · Genetics · doi:10.1093/genetics/105.2.437 · Cited by 3,112
Pairwise comparisons of mitochondrial DNA sequences in stable and exponentially growing populations.
Slatkin, M., & Hudson, R. R. (1991) · Genetics · doi:10.1093/genetics/129.2.555 · Cited by 2,346
Gene genealogies and the coalescent process.
Hudson, R. R. (1990) · Medical Entomology and Zoology · Cited by 1,838
History and Geography of Human Genes
Piazza, A. (1994) · Advances in forensic haemogenetics · doi:10.1007/978-3-642-78782-9_1 · Cited by 1,639
STATISTICAL PROPERTIES OF THE NUMBER OF RECOMBINATION EVENTS IN THE HISTORY OF A SAMPLE OF DNA SEQUENCES
Hudson, R. R., & Kaplan, N. L. (1985) · Genetics · doi:10.1093/genetics/111.1.147 · Cited by 1,555
The effect of change in population size on DNA polymorphism.
Tajima, F. (1989) · Genetics · doi:10.1093/genetics/123.3.597 · Cited by 1,417
Neandertal DNA Sequences and the Origin of Modern Humans
Krings, M., Stone, A. C., Schmitz, R. W., Krainitzki, H., Stoneking, M., & Pääbo, S. (1997) · Cell · doi:10.1016/s0092-8674(00)80310-4 · Cited by 1,339
African Populations and the Evolution of Human Mitochondrial DNA
Vigilant, L., Stoneking, M., Harpending, H. C., Hawkes, K., & Wilson, A. C. (1991) · Science · doi:10.1126/science.1840702 · Cited by 1,338
GENETIC EVIDENCE FOR A PLEISTOCENE POPULATION EXPLOSION
Rogers, A. R. (1995) · Evolution · doi:10.1111/j.1558-5646.1995.tb02297.x · Cited by 1,073
Genetic and Fossil Evidence for the Origin of Modern Humans
Stringer, C. B., & Andrews, P. (1988) · Science · doi:10.1126/science.3125610 · Cited by 970
Properties of a neutral allele model with intragenic recombination
Hudson, R. R. (1983) · Theoretical Population Biology · doi:10.1016/0040-5809(83)90013-8 · Cited by 816
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
Tishkoff, S. A., Dietzsch, E., Speed, W., Pakstis, A. J., Kidd, J. R., Cheung, K., Bonné-Tamir, B., Santachiara-Benerecetti, A. S., Moral, P., Krings, M., et al. (1996) · Science · doi:10.1126/science.271.5254.1380 · Cited by 587
Paleolithic Population Growth Pulses Evidenced by Small Animal Exploitation
Stiner, M. C., Munro, N. D., Surovell, T. A., Tchernov, E., & Bar‐Yosef, O. (1999) · Science · doi:10.1126/science.283.5399.190 · Cited by 568
The Origins of modern humans : a world survey of the fossil evidence
Smith, F. H., & Spencer, F. (1984) · Alan R. Liss eBooks · Cited by 525
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
Nickerson, D. A., Taylor, S. L., Weiss, K. M., Clark, A. G., Hutchinson, R. G., Stengård, J., Salomaa, V. V., Vartiainen, E. A., Boerwinkle, E., & Sing, C. F. (1998) · Nature Genetics · doi:10.1038/907 · Cited by 475
Sequence variation in the human angiotensin converting enzyme
Rieder, M. J., Taylor, S. L., Clark, A. G., & Nickerson, D. A. (1999) · Nature Genetics · doi:10.1038/8760 · Cited by 470
Lower Pleistocene Hominids and Artifacts from Atapuerca-TD6 (Spain)
Carbonell, E., de Castro, J. M. B., Arsuaga, J. L., Fernández-Lomana, J. C. D., Rosas, A., Cuenca‐Bescós, G., Sala, R., Mosquera, M., & Álvarez, X. P. R. (1995) · Science · doi:10.1126/science.7638598 · Cited by 462
The skull of Sinanthropus pekinensis : a comparative study on a primitive hominid skull
Weidenreich, F. (1943) · Geological Survey of China eBooks · Cited by 442
Multiple dispersals and modern human origins
Lahr, M. M., & Foley, R. (1994) · Evolutionary Anthropology Issues News and Reviews · doi:10.1002/evan.1360030206 · Cited by 425
Age of the Earliest Known Hominids in Java, Indonesia
Swisher, C. C., Curtis, G. H., Jacob, T., Getty, A. G., Suprijo, A., & Widiasmoro (1994) · Science · doi:10.1126/science.8108729 · Cited by 422
Mode 3 Technologies and the Evolution of Modern Humans
Foley, R., & Lahr, M. M. (1997) · Cambridge Archaeological Journal · doi:10.1017/s0959774300001451 · Cited by 420
Untitled work
(1997) · PubMed · Cited by 412
A Coalescent Estimator of the Population Recombination Rate
Hey, J., & Wakeley, J. (1997) · Genetics · doi:10.1093/genetics/145.3.833 · Cited by 411
Ancestral Inference from Samples of DNA Sequences with Recombination
Griffiths, R., & Marjoram, P. (1996) · Journal of Computational Biology · doi:10.1089/cmb.1996.3.479 · Cited by 394
Estimating the recombination parameter of a finite population model without selection
Hudson, R. R. (2007) · Genetics Research · doi:10.1017/s0016672308009610 · Cited by 391
The early Upper Paleolithic human skeleton from the Abrigo do Lagar Velho (Portugal) and modern human emergence in Iberia
Duarte, C., Maurício, J., Pettitt, P., Souto, P., Trinkaus, E., van der Plicht, H., & Zilhão, J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7604 · Cited by 384
Oxford Surveys in Evolutionary Biology
Loxdale, H. D., Harvey, P., & Partridge, L. (1991) · Journal of Animal Ecology · doi:10.2307/5468 · Cited by 361
A late Neanderthal associated with Upper Palaeolithic artefacts
Hublin, J., Spoor, F., Braun, M., Zonneveld, F. W., & Condémi, S. (1996) · Nature · doi:10.1038/381224a0 · Cited by 357
Estimating the recombination parameter of a finite population model without selection
Hudson, R. R. (1987) · Genetics Research · doi:10.1017/s0016672300023776 · Cited by 357
The human colonisation of Australia: optical dates of 53,000 and 60,000 years bracket human arrival at Deaf Adder Gorge, Northern Territory
Roberts, R. G., Jones, R., Spooner, N. A., Head, M. J., Murray, A. S., & Smith, M. A. (1994) · Quaternary Science Reviews · doi:10.1016/0277-3791(94)90080-9 · Cited by 330
Latest Homo erectus of Java: Potential Contemporaneity with Homo sapiens in Southeast Asia
Swisher, C. C., Rink, W. J., Antón, S. C., Schwarcz, H. P., Curtis, G. H., Suprijo, A., & Widiasmoro (1996) · Science · doi:10.1126/science.274.5294.1870 · Cited by 323
The “Eve” Hypotheses: A Genetic Critique and Reanalysis
Templeton, A. R. (1993) · American Anthropologist · doi:10.1525/aa.1993.95.1.02a00030 · Cited by 295
Modern homo sapiens origins : A general theory of hominid evolution involving the fossil evidence from East Asia
Wolpoff, M. H. (1984) · Medical Entomology and Zoology · Cited by 256
DNA sequence variation in a non-coding region of low recombination on the human X chromosome
Kaessmann, H., Heißig, F., von Haeseler, A., & Pääbo, S. (1999) · Nature Genetics · doi:10.1038/8785 · Cited by 245
Pairwise comparisons of mitochondrial DNA sequences in subdivided populations and implications for early human evolution.
Marjoram, P., & Donnelly, P. (1994) · Genetics · doi:10.1093/genetics/136.2.673 · Cited by 245
Early Homo and associated artefacts from Asia
Huang, W., Ciochon, R. L., Yumin, G., Larick, R. R., Qiren, F., Schwarcz, H. P., Yonge, C. J., de Vos, J., & Rink, W. J. (1995) · Nature · doi:10.1038/378275a0 · Cited by 238
X chromosome evidence for ancient human histories
Harris, E. E., & Hey, J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3320 · Cited by 230
Recombination and the power of statistical tests of neutrality
Wall, J. D. (1999) · Genetics Research · doi:10.1017/s0016672399003870 · Cited by 200
Self-citation
On the Probability of Neanderthal Ancestry
Nordborg, M. (1998) · The American Journal of Human Genetics · doi:10.1086/302052 · Cited by 187
Inference of Population History Using a Likelihood Approach
Weiss, G., & von Haeseler, A. (1998) · Genetics · doi:10.1093/genetics/149.3.1539 · Cited by 175
Minisatellite diversity supports a recent African origin for modern humans
Armour, J. A. L., Anttinen, T., May, C. A., Vega, E., Sajantila, A., Kidd, J. R., Kídd, K. K., Bertranpetit, J., Pääbo, S., & Jeffreys, A. J. (1996) · Nature Genetics · doi:10.1038/ng0696-154 · Cited by 164
Continuity or Replacement; Controversies in Homo Sapiens Evolution
Tattersall, I. (1993) · Museum Anthropology · doi:10.1525/mua.1993.17.1.88 · Cited by 162
The Multiregional Model of modern human origins: a reassessment of its morphological basis
Lahr, M. M. (1994) · Journal of Human Evolution · doi:10.1006/jhev.1994.1003 · Cited by 144
Thermoluminescence dating of the late Neanderthal remains from Saint-Césaire
Mercier, N., Valladas, H., Joron, J. L., Reyss, J., Lévêque, F., & Vandermeersch, B. (1991) · Nature · doi:10.1038/351737a0 · Cited by 143
Explaining modern man: Evolutionists Versus migrationists
Howells, W. W. (1976) · Journal of Human Evolution · doi:10.1016/0047-2484(76)90088-9 · Cited by 138
The coalescent in two partially isolated diffusion populations
Takahata, N. (1988) · Genetics Research · doi:10.1017/s0016672300027683 · Cited by 128
X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content.Preprint
Nagaraja, R., MacMillan, S., Kere, J., Jones, C., Griffin, S., Schmatz, M., Terrell, J., Shomaker, M., Jermak, C., Hott, C., et al. (1997) · Genome Research · doi:10.1101/gr.7.3.210 · Cited by 112
Estimating the age of the common ancestor of a sample of DNA sequences
Fu, Y., & Li, W. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025753 · Cited by 107
Facts and Artifacts of Ancient DNA
Lindahl, T. L. (1997) · Cell · doi:10.1016/s0092-8674(00)80306-2 · Cited by 103
A Physical Map of Human Chromosome 7: An Integrated YAC Contig Map with Average STS Spacing of 79 kbPreprint
Bouffard, G. G., Idol, J. R., Braden, V. V., Iyer, L. M., Cunningham, A., Weintraub, L. A., Touchman, J. W., Tidwell, R. M., Peluso, D. C., Fulton, R. S., et al. (1997) · Genome Research · doi:10.1101/gr.7.7.673 · Cited by 89
Nuclear DNA diversity in worldwide distributed human populations
Ziętkiewicz, E., Yotova, V., Jarník, M., Korab-Laskowska, M., Kídd, K. K., Modiano, D., Scozzari, R., Stoneking, M., Tishkoff, S. A., Batzer, M. A., et al. (1997) · Gene · doi:10.1016/s0378-1119(97)00408-3 · Cited by 88
The Mousterian site of Zafarraya (Andalucia, Spain): dating and implications on the palaeolithic peopling processes of Western Europe
Hublin, J., Ruíz, C. B., Lara, P. M., Fontugne, M., & Reyss, J. (1995) · HAL · Cited by 45
A molecular handle on the Neanderthals
Ward, R. H., & Stringer, C. B. (1997) · Nature · doi:10.1038/40746 · Cited by 45
Interpretations of Multiregional Evolution
Wolpoff, M. H., Tishkoff, S. A., Kídd, K. K., & RISCH, N. J. (1996) · Science · doi:10.1126/science.274.5288.704d · Cited by 32
DNA From an Extinct Human
Kahn, P., & Gibbons, A. (1997) · Science · doi:10.1126/science.277.5323.176 · Cited by 28
The evolution of modern human diversity
Rightmire, G. P. (1996) · Trends in Ecology & Evolution · doi:10.1016/0169-5347(96)88907-5 · Cited by 19
Interpretations of Multiregional Evolution
Wolpoff, M. H. (1996) · Science · doi:10.1126/science.274.5288.704-b · Cited by 13
Untitled work
(1999) · doi:10.1002/(sici)1096-8644(199907)109:3

Flagged first, then by citations

2 of the 62 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

Bräuer, 1984, The ‘Afro-European sapiens hypothesis’ and hominid evolution in East Asia during the late Middle and Upper Pleistocene, Cour. Forschungsinst. Senckenb., 69, 145
Hublin, 1998, Climatic changes, paleogeography, and the evolution of the neandertals, 295
Nordborg, 2000, On detecting ancient admixture
Smith, 1992, The role of continuity in modern human origins, 145

Sorted by citations

Linkage disequilibrium--understanding the evolutionary past and mapping the medical future.
Slatkin, M. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2361 · Cited by 1,614
Testing for ancient admixture between closely related populations
Durand, E. Y., Patterson, N., Reich, D., & Slatkin, M. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr048 · Cited by 1,375
Genealogical trees, coalescent theory and the analysis of genetic polymorphisms
Rosenberg, N. A., & Nordborg, M. (2002) · Nature Reviews Genetics · doi:10.1038/nrg795 · Cited by 750
Haplotype blocks and linkage disequilibrium in the human genome
Wall, J. D., & Pritchard, J. K. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1123 · Cited by 642
Self-citation
Evidence for archaic adaptive introgression in humans
Racimo, F., Sankararaman, S., Nielsen, R., & Huerta-Sánchez, E. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3936 · Cited by 521

See all 116

Authors: Wall, J. D.
Affiliations: University of Chicago (US)
Corresponding author: Wall, Jeffrey D
ORCID: Wall, Jeffrey D
Venue: Genetics
Publisher: Oxford University Press (OUP)
Published: 2000-03-01
Volume: 154
Issue: 3
Pages: 1271-1279
ISSN: 0016-6731 (ISSN-L)
1943-2631
DOI: 10.1093/genetics/154.3.1271
OpenAlex: W2107737723
Cited by: 116
References: 62
Citations by year: 2025: 2 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 7 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 3 · 2013: 5 · 2012: 4
FWCI: 4.88
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: Genetics (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
Social Sciences › Anthropology › Pleistocene-Era Hominins and Archaeology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
Keywords: Neanderthal admixture, human evolution, population structure, demographic models, sequence variation, sample size requirements, multiregional model
MeSH terms: Humans, Models, Genetic, Polymorphism, Genetic, Models, Statistical

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Detecting Ancient Admixture in Humans Using Sequence Polymorphism Data

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