Executive Function, Working Memory, and Medication Adherence Among Older Adults
Abstract
The purpose of this study was to investigate the association between cognitive processes and medication adherence among community-dwelling older adults. Ninety-five participants (M = 78 years) completed a battery of cognitive assessments including measures of executive function, working memory, cued recall, and recognition memory. Medication adherence was examined over 8 weeks for one prescribed medicine by use of an electronic medication-monitoring cap. In a simultaneous regression, the composite of executive function and working memory tasks was the only significant predictor (beta =.44, p <.01). Findings suggest that assessments of executive function and working memory can be used to identify community-dwelling older adults who may be at risk for failure to take medicines as prescribed.
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Impairments in executive functioning make it more difficult to engage in Instrumental Daily Living Tasks (IADLs), such as paying bills, doing household tasks, managing money, and following health care regimes.
“For example, impairments in executive functioning make it more difficult to engage in Instrumental Daily Living Tasks (IADLs), such as paying bills, doing household tasks, managing money, and following health care regimes, such as taking pharmaceuticals as prescribed (Insel et al. 2006).”
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- Authors
- Insel, K., Morrow, D., Brewer, B., & Figueredo, A.
- Affiliations
- University of Arizona (US)
- University of Illinois Urbana-Champaign (US)
- Lincoln Medical Center (US)
- Corresponding author
- Insel, K.
- ORCID
- Venue
- The Journals of Gerontology Series B: Psychological Sciences and Social Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-03-01
- Volume
- 61
- Issue
- 2
- Pages
- P102-P107
- ISSN
- 1079-5014 (ISSN-L)
- 1758-5368
- OpenAlex
- W2123197549
- Cited by
- 343
- References
- 1
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 11 · 2023: 7 · 2022: 24 · 2021: 19 · 2020: 22 · 2019: 25 · 2018: 15 · 2017: 25 · 2016: 24 · 2015: 20 · 2014: 19 · 2013: 19 · 2012: 23
- FWCI
- 6.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journals of Gerontology Series B (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1r03ag019930-01)
- University of Texas Health Science Center at San Antonio
- National Institute on Aging (1 R03 AG19930-01)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- executive function, working memory, medication adherence, older adults, community-dwelling older adults, cognitive assessment, electronic medication monitoring, cued recall, recognition memory
- MeSH terms
- Aged, Aged, 80 and over, Cognition Disorders, Demography, Depression, Female, Humans, Male, Memory Disorders, Neuropsychological Tests, Patient Compliance, Self Care, Severity of Illness Index, Socioeconomic Factors
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