Cited by 188Dementia and Cognitive Impairment ResearchCardiovascular Health and Risk FactorsNeurological Disease Mechanisms and Treatments

Cardiovascular Disease Risk Factors and Cognition in the Elderly

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Leritz, Elizabeth C., McGlinchey, Regina E., Kellison, Ida, Rudolph, James L., Milberg, William P.·2011·Current Cardiovascular Risk Reports

Abstract

While it is relatively widely known that cardiovascular disease (CVD) can result in cognitive decline, it is becoming increasingly clearer that actual risk factors for CVD, such as high blood pressure, diabetes, and obesity are also associated with alterations to brain structure and cognition. The prevalence of CVD risk factors increase exponentially with age and are often overlooked as a source of cognitive changes that are otherwise thought to be part of the 'normal' aging process. Associated cognitive changes are observed even at levels of risk that would be considered subclinical by current diagnostic convention, and are often significant enough to interfere with daily functional abilities. More importantly, if not controlled, CVD risk can lead to further decline, including cerebrovacsular disease and dementia. Thus, it is critically important to consider these factors in the elderly and we recommend more routine cognitive screenings, particularly when CVD risk factors are involved.

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  • Poor cardiovascular health negatively affects cognitive abilities.

    “It has been known for decades that poor cardiovascular health negatively affects cognitive abilities (87, 88)”

    From Glymphatic failure as a final common pathway to dementia (2020) · cites this paper as [88]

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Authors
Leritz, E. C., McGlinchey, R. E., Kellison, I., Rudolph, J. L., & Milberg, W. P.
Affiliations
  • Geriatric Research Education and Clinical Center (US)
  • Brigham and Women's Hospital (US)
  • VA Boston Healthcare System (US)
Corresponding author
Leritz, Elizabeth C.
Venue
Current Cardiovascular Risk Reports
Published
2011-07-15
Volume
5
Issue
5
Pages
407-412
ISSN
  • 1932-9520 (ISSN-L)
  • 1932-9563
OpenAlex
W2059615097
Cited by
188
References
35
Citations by year
2026: 5 · 2025: 20 · 2024: 26 · 2023: 17 · 2022: 22 · 2021: 25 · 2020: 23 · 2019: 20 · 2018: 6 · 2017: 11 · 2016: 3 · 2015: 3 · 2013: 4 · 2012: 3
FWCI
1.53
Type
journal article
Language
en
Open access
Locations
  • Current Cardiovascular Risk Reports (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Neurological Disorders and Stroke (K23NS062148)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Keywords
cardiovascular risk factors, cognitive decline, older adults, hypertension, diabetes mellitus, obesity, brain structure, dementia, cerebrovascular disease, cognitive screening, aging

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