Cardiovascular Disease Risk Factors and Cognition in the Elderly
Open accessAbstract
While it is relatively widely known that cardiovascular disease (CVD) can result in cognitive decline, it is becoming increasingly clearer that actual risk factors for CVD, such as high blood pressure, diabetes, and obesity are also associated with alterations to brain structure and cognition. The prevalence of CVD risk factors increase exponentially with age and are often overlooked as a source of cognitive changes that are otherwise thought to be part of the 'normal' aging process. Associated cognitive changes are observed even at levels of risk that would be considered subclinical by current diagnostic convention, and are often significant enough to interfere with daily functional abilities. More importantly, if not controlled, CVD risk can lead to further decline, including cerebrovacsular disease and dementia. Thus, it is critically important to consider these factors in the elderly and we recommend more routine cognitive screenings, particularly when CVD risk factors are involved.
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Poor cardiovascular health negatively affects cognitive abilities.
“It has been known for decades that poor cardiovascular health negatively affects cognitive abilities (87, 88)”
From Glymphatic failure as a final common pathway to dementia (2020) · cites this paper as [88]
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Glymphatic failure as a final common pathway to dementia
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- Authors
- Leritz, E. C., McGlinchey, R. E., Kellison, I., Rudolph, J. L., & Milberg, W. P.
- Affiliations
- Geriatric Research Education and Clinical Center (US)
- Brigham and Women's Hospital (US)
- VA Boston Healthcare System (US)
- Corresponding author
- Leritz, Elizabeth C.
- Venue
- Current Cardiovascular Risk Reports
- Published
- 2011-07-15
- Volume
- 5
- Issue
- 5
- Pages
- 407-412
- ISSN
- 1932-9520 (ISSN-L)
- 1932-9563
- PMC
- PMC3245189
- OpenAlex
- W2059615097
- Cited by
- 188
- References
- 35
- Citations by year
- 2026: 5 · 2025: 20 · 2024: 26 · 2023: 17 · 2022: 22 · 2021: 25 · 2020: 23 · 2019: 20 · 2018: 6 · 2017: 11 · 2016: 3 · 2015: 3 · 2013: 4 · 2012: 3
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Cardiovascular Risk Reports (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (K23NS062148)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Keywords
- cardiovascular risk factors, cognitive decline, older adults, hypertension, diabetes mellitus, obesity, brain structure, dementia, cerebrovascular disease, cognitive screening, aging
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