The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.
Structural and mechanistic classification of uronic acid-containing polysaccharide lyases
Open accessAbstract
Polysaccharide lyases (PLs) have been assigned to 21 families based on their sequences, with ~ 50 singletons awaiting further classification. For 19 of these families, the structure of at least one protein is known. In this review, we have analyzed the available structural information and show that presently known PL families belong to six general folds. Only two general catalytic mechanisms have been observed among these PLs: (1) metal-assisted neutralization of the acidic group of the sugar next to the cleaved bond, with, rather unusually, arginine or lysine playing the role of Brønsted base and (2) neutralization of the acidic group on the sugar by a close approach of an amino or acidic group forcing its protonation and Tyr or Tyr-His acting as the Brønsted base and acid.
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A hierarchical classification of polysaccharide lyases for glycogenomics
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Alginate Oligosaccharides: Production, Biological Activities, and Potential Applications
Liu, J., Yang, S., Li, X., Yan, Q., Reaney, M. J. T., & Jiang, Z. (2019) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12494 · Cited by 311
Collén, P. N., Jeudy, A., Sassi, J.-F., Groisillier, A., Czjzek, M., Coutinho, P. M., & Helbert, W. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.537480 · Cited by 47
Weerasekera, R., Moreau, A., Huang, X., Nam, K.-M., Hinbest, A. J., Huynh, Y., Liu, X., Ashwood, C., Pepi, L. E., Paulson, E., et al. (2024) · PLOS Pathogens · doi:10.1371/journal.ppat.1012750 · Cited by 9
Metadata
- Authors
- Garron, M.-L., & Cygler, M.
- Venue
- Glycobiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-08-30
- Volume
- 20
- Issue
- 12
- Pages
- 1547-1573
- ISSN
- 0959-6658 (ISSN-L)
- 1460-2423
- OpenAlex
- W2168621094
- Cited by
- 285
- References
- 79
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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