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An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors
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“studies suggest that ubiquination of sperm-mitochondria could be required for the initial step of allophagy [1108,1109]”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [1108]
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“This autophagy targeting requires both the ubiquitination of substrates and the loss of sperm mitochondrial membrane potential [1108,1110,1111].”
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“The autophagy receptor ALLO-1 and its kinase IKKE-1 are required for the recruitment of LGG-1 around sperm-inherited organelles [1108].”
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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
Arrasate, M., Mitra, S., Schweitzer, E. S., Segal, M. R., & Finkbeiner, S. (2004) · Nature · doi:10.1038/nature02998 · Cited by 1,979
Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G. P., Davies, S. W., Lehrach, H., & Wanker, E. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80514-0 · Cited by 1,291 · cited 1×
“Aggregation of bacterially expressed huntingtin fragments and synthetic polyQ peptides can be accelerated by adding aggregated polyQ seeds in vitro, supporting a nucleated growth assembly mechanism similar to amyloid formation (8,12,15,16).”
Altered proteasome structure, function, and oxidation in aged muscle.
Ferrington, D. A., Husom, A. D., & Thompson, L. V. (2005) · The FASEB Journal · doi:10.1096/fj.04-2578fje · Cited by 259
Zhang, S., Binari, R., Zhou, R., & Perrimon, N. (2010) · Genetics · doi:10.1534/genetics.109.112516 · Cited by 160
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy · doi:10.1080/15548627.2015.1100356 · Cited by 5,894
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy · doi:10.4161/auto.19496 · Cited by 3,996
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
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Metadata
- Authors
- Fuentealba, R. A., Marasa, J., Diamond, M. I., Piwnica-Worms, D., & Weihl, C. C.
- Venue
- Human Molecular Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-11-03
- Volume
- 21
- Issue
- 3
- Pages
- 664-680
- ISSN
- 1460-2083
- 0964-6906
- Cited by
- 28
- References
- 4
- Language
- en
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