The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Intrauterine insemination treatment in subfertility: an analysis of factors affecting outcome
Abstract
A total of 811 intrauterine insemination (IUI) cycles in which clomiphene citrate/human menopausal gonadotrophin (HMG) was used for ovarian stimulation were analysed retrospectively to identify prognostic factors regarding treatment outcome. The overall pregnancy rate was 12.6% per cycle, the multiple pregnancy rate 13.7%, and the miscarriage rate 23.5%. Logistic regression analysis revealed five predictive variables as regards pregnancy: number of the treatment cycle (P = 0.009), duration of infertility (P = 0.017), age (P = 0.028), number of follicles (P = 0.031) and infertility aetiology (P = 0.045). The odds ratios for age < 40 years, unexplained infertility aetiology (versus endometriosis) and duration of infertility < or = 6 years were 3.24, 2.79 and 2.33, respectively. A multifollicular ovarian response to clomiphene citrate/HMG resulted in better treatment success than a monofollicular response, and 97% of the pregnancies were obtained in the first four treatment cycles. The results indicate that clomiphene citrate/HMG/IUI is a useful and cost-effective treatment option in women < 40 years of age with infertility duration < or = 6 years, who do not suffer from endometriosis.
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Cites
Hughes, E. G. (1997) · Human Reproduction · doi:10.1093/humrep/12.9.1865 · Cited by 275
Pellicer, A., Valbuena, D., Bauset, C., Albert, C., Bonilla-Musoles, F., Remohı́, J., & Simón, C. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00085-5 · Cited by 73
Kahn, J. A., Sunde, A., Koskemies, A., von Düring, V., Sørdal, T., Christensen, F., & Molne, K. (1993) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a138161 · Cited by 60
Relationship of within patient semen variability to outcome of intrauterine insemination
McGovern, P., Quagliarello, J., & Arny, M. (1989) · Fertility and Sterility · doi:10.1016/s0015-0282(16)60736-7 · Cited by 20
Cited by
Endometriosis‐associated infertility: aspects of pathophysiological mechanisms and treatment options
Tanbo, T., & Fedorcsak, P. (2017) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/aogs.13082 · Cited by 432
Role of oxidative stress in endometriosis
Gupta, S., Agarwal, A., Krajcir, N., & Alvarez, J. G. (2006) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)62026-3 · Cited by 240
van Weert, J.-M., Repping, S., Van Voorhis, B. J., van der Veen, F., Bossuyt, P. M. M., & Mol, B. W. J. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.01.042 · Cited by 138
Endometriosis and infertility: Insights into the causal link and management strategies
Tomassetti, C., & D'Hooghe, T. (2018) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2018.06.002 · Cited by 132
Opøien, H. K., Fedorcsak, P., Åbyholm, T., & Tanbo, T. (2011) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2011.06.002 · Cited by 120
Metadata
- Authors
- Nuojua-Huttunen, S.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-03-01
- Volume
- 14
- Issue
- 3
- Pages
- 698-703
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W1979787337
- Cited by
- 254
- References
- 4
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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