Cited by 294Reproductive Biology and FertilityOvarian function and disordersReproductive biology and impacts on aquatic species

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Anti-Müllerian hormone inhibits initiation of growth of human primordial ovarian follicles in vitro

Carlsson, I.B.·2006·Human Reproduction

DOI 10.1093/humrep/del165

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Abstract

BACKGROUND: Anti-Müllerian hormone (AMH) inhibits the initiation of the development and early growth of mouse ovarian follicles. Furthermore, the ovarian follicle pool diminishes prematurely in AMH-knockout mice. In this study, we examined whether AMH plays a similar role in humans, controlling ovarian follicle growth. METHODS: Human ovarian cortical tissue biopsy specimens were cut into small pieces and cultured for 7 days in medium containing rat recombinant AMH at 0, 10, 30 or 100 ng/ml. The developmental stages and viability of the follicles were evaluated from histological sections. RESULTS: Similar to previous studies, significant initiation of follicle growth was observed in almost all culture media, as demonstrated by a significantly smaller proportion of primordial follicles (14-26%) compared with non-cultured control tissue (56%). The exception was tissue in medium supplemented with AMH at 100 ng/ml. Here, the proportion of primordial follicles was not significantly different from that in non-cultured tissue; furthermore, it was significantly greater than that in vehicle control cultures and cultures containing AMH at 10 ng/ml, indicating the inhibition of growth initiation. Viability was unaffected by the presence of AMH when compared with tissues in control media. CONCLUSIONS: Recombinant AMH at a concentration of 100 ng/ml has an inhibitory effect on early human ovarian follicular development in vitro, suppressing the initiation of primordial follicle growth.

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Weenen, C. (2004) · Molecular Human Reproduction · doi:10.1093/molehr/gah015 · Cited by 1,298
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Durlinger, A. L. L., Kramer, P., Karels, B., de Jong, F. H., Uilenbroek, J. T. J., Grootegoed, J. A., & Themmen, A. P. N. (1999) · Endocrinology · doi:10.1210/endo.140.12.7204 · Cited by 1,075
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Anti-Mullerian Hormone Attenuates the Effects of FSH on Follicle Development in the Mouse Ovary
Durlinger, A. L. L., Gruijters, M. J. G., Kramer, P., Karels, B., Kumar, T. R., Matzuk, M. M., Rose, U. M., de Jong, F. H., Uilenbroek, J. T. J., Grootegoed, J. A., et al. (2001) · Endocrinology · doi:10.1210/endo.142.11.8486 · Cited by 772
Dynamics of follicular growth in the human: a model from preliminary results
Gougeon, A. (1986) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a136365 · Cited by 741
Müllerian-inhibiting substance function during mammalian sexual development.
Behringer, R., Finegold, M., & Cate, R. (1994) · Cell · doi:10.1016/0092-8674(94)90251-8 · Cited by 706
Anti-müllerian hormone and anti-müllerian hormone type II receptor messenger ribonucleic acid expression in rat ovaries during postnatal development, the estrous cycle, and gonadotropin-induced follicle growth.
Baarends, W. M., Uilenbroek, J. T. J., Kramer, P. F., Hoogerbrugge, J. W., van Leeuwen, E. C. M., Themmen, A. P. N., & Grootegoed, J. A. (1995) · Endocrinology · doi:10.1210/endo.136.11.7588229 · Cited by 462
Anti-Müllerian hormone and folliculogenesis
Visser, J. A., & Themmen, A. P. N. (2005) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2004.09.008 · Cited by 462
Expression of Anti-Müllerian Hormone during Normal and Pathological Gonadal Development: Association with Differentiation of Sertoli and Granulosa Cells1
Meyts, E. R., Jørgensen, N., Græm, N., Müller, J., Cate, R. L., & Skakkebæk, N. E. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6047 · Cited by 375

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Authors: Carlsson, I. B.
Affiliations: Karolinska University Hospital (SE)
Corresponding author: Carlsson, I.B.
Venue: Human Reproduction
Publisher: Oxford University Press (OUP)
Published: 2006-06-03
Volume: 21
Issue: 9
Pages: 2223-2227
ISSN: 0268-1161 (ISSN-L)
1460-2350
DOI: 10.1093/humrep/del165
OpenAlex: W2131854962
Cited by: 294
References: 25
Citations by year: 2026: 8 · 2025: 13 · 2024: 10 · 2023: 15 · 2022: 9 · 2021: 26 · 2020: 17 · 2019: 23 · 2018: 14 · 2017: 13 · 2016: 12 · 2015: 17 · 2014: 21 · 2013: 16 · 2012: 16
FWCI: 10.66
Type: journal article
Language: en
Open access: closed
Locations: Human Reproduction (publishedVersion)
PubMed (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
Keywords: anti-Müllerian hormone, primordial follicles, ovarian follicle development, folliculogenesis, ovarian cortical tissue, follicle viability, human ovary
MeSH terms: Adult, Animals, Female, Glycoproteins, Ovarian Follicle, Humans, Ovary, Testicular Hormones, Mice, Knockout, Cell Culture Techniques, Cell Proliferation, Mice, Rats, Anti-Mullerian Hormone

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Anti-Müllerian hormone inhibits initiation of growth of human primordial ovarian follicles in vitro

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