The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women
Open accessAbstract
BACKGROUND: Obesity is increasing rapidly among women all over the world. Obesity is a known risk factor for subfertility due to anovulation, but it is unknown whether obesity also affects spontaneous pregnancy chances in subfertile, ovulatory women. METHODS: We evaluated whether obesity affected the chance of a spontaneous pregnancy in a prospectively assembled cohort of 3029 consecutive subfertile couples. Women had to be ovulatory and had to have at least one patent tube, whereas men had to have a normal semen analysis. Time to spontaneous ongoing pregnancy within 12 months was the primary endpoint. RESULTS: The probability of a spontaneous pregnancy declined linearly with a body mass index (BMI) over 29 kg/m(2). Corrected for possible related factors, women with a high BMI had a 4% lower pregnancy rate per kg/m(2) increase [hazard ratio: 0.96 (95% CI 0.91-0.99)]. CONCLUSIONS: These results indicate that obesity is associated with lower pregnancy rates in subfertile ovulatory women.
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Cited by
Garvey, W. T., Mechanick, J. I., Brett, E. M., Garber, A. J., Hurley, D. L., Jastreboff, A. M., Nadolsky, K., Pessah-Pollack, R., & Plodkowski, R. (2016) · Endocrine Practice · doi:10.4158/ep161365.gl · Cited by 1,914
Obesity and female infertility: potential mediators of obesity's impact
Broughton, D. E., & Moley, K. H. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.01.017 · Cited by 845
Robker, R. L., Akison, L. K., Bennett, B. D., Thrupp, P. N., Chura, L. R., Russell, D. L., Lane, M., & Norman, R. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2648 · Cited by 384
Obesity, Polycystic Ovary Syndrome, and Infertility: A New Avenue for GLP-1 Receptor Agonists
Cena, H., Chiovato, L., & Nappi, R. E. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa285 · Cited by 356
Female Obesity and Infertility
Talmor, A., & Dunphy, B. (2015) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2014.10.014 · Cited by 320
Metadata
- Authors
- van der Steeg, J. W., Steures, P., Eijkemans, M. J. C., Habbema, J. D. F., Hompes, P. G. A., Burggraaff, J. M., Oosterhuis, G. J. E., Bossuyt, P. M. M., van der Veen, F., & Mol, B. W. J.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-12-14
- Volume
- 23
- Issue
- 2
- Pages
- 324-328
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2095829298
- Cited by
- 512
- References
- 4
- FWCI
- 13.95
- Type
- journal article
- Language
- en
- Open access
- green
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- van der Steeg, J. W., Steures, P., Eijkemans, M. J. C., Habbema, J. D. F., Hompes, P. G. A., Burggraaff, J. M., Oosterhuis, G. J. E., Bossuyt, P. M. M., van der Veen, F., & Mol, B. W. J. (2007). Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women. Human Reproduction. https://doi.org/10.1093/humrep/dem371
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