The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Female and male lifestyle habits and IVF: what is known and unknown
Abstract
There is no greater tribute to the importance and efficacy of IVF than the fact that >1 x 10(6) babies have been born to infertile couples since its clinical introduction in 1978. Despite enormous advances regarding the technical aspects of the IVF procedure, the parents' contribution has virtually been ignored when considering aspects that influence success rates. This systematic review focuses on the effects of female and male lifestyle habits (specifically: smoking, alcohol and caffeine use, and psychological stress) on the reproductive endpoints of IVF (i.e. oocyte aspiration, fertilization, embryo transfer, achievement of a pregnancy, live birth delivery, and perinatal outcomes, e.g. low birthweight, multiple gestations). What is currently known in the field of lifestyle habits and IVF? There is compelling evidence that smoking has a negative influence on IVF outcomes, whereas for stress, the evidence is suggestive but insufficient due to the heterogeneity of studies. The evidence for the effects of alcohol and caffeine on IVF is inadequate, and therefore unknown, due to the scarcity of studies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Moreover, evidence shows that smoking reduces the success of fertility treatments such as IVF and ICSI (Klonoff-Cohen 2005, Mínguez-Alarcón 2018, Practice Committee 2018, Waylen 2008).”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Klonoff-Cohen 2005
Citations
Cites
Clinical Epidemiology: A Basic Science for Clinical Medicine.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-825_9 · Cited by 3,497
Conception to ongoing pregnancy: the 'black box' of early pregnancy loss
Macklon, N. (2002) · Human Reproduction Update · doi:10.1093/humupd/8.4.333 · Cited by 800
Smoking and female infertility: a systematic review and meta-analysis
Augood, C., Duckitt, K., & Templeton, A. A. (1998) · Human Reproduction · doi:10.1093/humrep/13.6.1532 · Cited by 510
Klonoff-Cohen, H. S., Chu, E., Natarajan, L., & Sieber, W. J. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)02008-8 · Cited by 369
Self-citationClinical management of low ovarian response to stimulation for IVF: a systematic review
Tarlatzis, B. C. (2003) · Human Reproduction Update · doi:10.1093/humupd/dmg007 · Cited by 364
Psychological evaluation and support in a program of in vitro fertilization and embryo transfer
Freeman, E. W., Boxer, A. S., Rickels, K., Tureck, R., & Mastroianni, L. (1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48316-0 · Cited by 319
Women's experience of IVF: a follow-up study
Hammarberg, K. (2001) · Human Reproduction · doi:10.1093/humrep/16.2.374 · Cited by 308
Wallach, E. E., Stillman, R. J., Rosenberg, M. J., & Sachs, B. P. (1986) · Fertility and Sterility · doi:10.1016/s0015-0282(16)49628-7 · Cited by 305
Smoking and male reproduction: a review
Vine, M. F. (1996) · International Journal of Andrology · doi:10.1111/j.1365-2605.1996.tb00523.x · Cited by 270
Smoking cigarettes is associated with increased sperm disomy in teenage men
Rubeš, J., Lowe, X. R., Moore, D. H., Perreault, S. D., Slott, V. L., Evenson, D. P., Selevan, S. G., & Wyrobek, A. J. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00261-1 · Cited by 245
Research works printed but not linked: 11
- 1989, Lancet, 1, 731
- 1989, Hum Reprod, 4, 29
- 2001, Cent Eur J Publ Hlth, 9, 64
- 1997, Fertil Steril, 68, 384
- 1995, Rom J Morphol Embryol, 41, 7
- 1978, Fertil Steril, 52, 495
- 2003, Acta Obstet Gynecol Scand, 82, 151
- 1997, Alcohol, 32, 113
- 2003, J Med Assoc Thai, 86, 425
- 2002, Nat Cell Biol, 4, s33
- 1996, Hum Reprod, 11, 95
Cited by
Sorted by citations
Homan, G. F., Davies, M., & Norman, R. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml056 · Cited by 546
“A recent review of lifestyle habits and IVF concluded that there was compelling evidence of the negative effect of smoking on IVF outcome (Klonoff-Cohen, 2005).”
BackgroundFrederiksen, Y., Farver-Vestergaard, I., Skovgård, N. G., Ingerslev, H. J., & Zachariae, R. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-006592 · Cited by 380
“Adjusted for publication bias (25)¶ – – – – – 0.”
Stress, distress and outcome of assisted reproductive technology (ART): a meta-analysis
Matthiesen, S. M. S., Frederiksen, Y., Ingerslev, H. J., & Zachariae, R. H. (2011) · Human Reproduction · doi:10.1093/humrep/der246 · Cited by 297
“…past two decades suggest that psychological stress and feelings of distress may reduce the chances of obtaining a viable pregnancy with IVF treatment (Demyttenaere et al., 1992, 1994; Thiering et al., 1993; Csemiczky et al., 2000; Kee et al., 2000; Smeenk et al., 2001, 2005; Klonoff-Cohen, 2005).”
BackgroundInfluentialLifestyle factors in people seeking infertility treatment – A review
Anderson, K. J., Nisenblat, V., & NORMAN, R. (2010) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/j.1479-828x.2009.01119.x · Cited by 275
Effects of cigarette smoking upon clinical outcomes of assisted reproduction: a meta-analysis
Waylen, A. L., Metwally, M., Jones, G. L., Wilkinson, A. J., & Ledger, W. J. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmn046 · Cited by 229
“A recent systematic review of the evidence revealed that smoking may affect rates of oocyte retrieval, IVF, embryo transfer, pregnancy and live birth delivery (Klonoff-Cohen, 2005).”
Background
Metadata
- Authors
- Klonoff-Cohen, H.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Klonoff-Cohen, H.
- ORCID
- Klonoff-Cohen, H.
- Venue
- Human Reproduction Update
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-03-01
- Volume
- 11
- Issue
- 2
- Pages
- 180-204
- ISSN
- 1355-4786 (ISSN-L)
- 1460-2369
- OpenAlex
- W2151606477
- Cited by
- 173
- References
- 105
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 4 · 2022: 5 · 2021: 15 · 2020: 5 · 2019: 7 · 2018: 6 · 2017: 9 · 2016: 7 · 2015: 9 · 2014: 9 · 2013: 11 · 2012: 12
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Human Reproduction Update (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- in vitro fertilization, lifestyle habits, smoking, alcohol consumption, caffeine consumption, psychological stress, IVF outcomes, oocyte aspiration, fertilisation (biology), embryo transfer, live birth, perinatal outcomes, low birth weight, multiple pregnancy, male infertility, female infertility
- MeSH terms
- Abortion, Spontaneous, Alcohol Drinking, Birth Weight, Caffeine, Embryo Transfer, Female, Fertilization in Vitro, Gestational Age, Humans, Infant, Newborn, Life Style, Male, Oocytes, Pregnancy, Pregnancy, Multiple, Smoking, Stress, Psychological, Multivariate Analysis, Sample Size, Pregnancy Rate
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
