The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Female and male lifestyle habits and IVF: what is known and unknown
Abstract
There is no greater tribute to the importance and efficacy of IVF than the fact that >1 x 10(6) babies have been born to infertile couples since its clinical introduction in 1978. Despite enormous advances regarding the technical aspects of the IVF procedure, the parents' contribution has virtually been ignored when considering aspects that influence success rates. This systematic review focuses on the effects of female and male lifestyle habits (specifically: smoking, alcohol and caffeine use, and psychological stress) on the reproductive endpoints of IVF (i.e. oocyte aspiration, fertilization, embryo transfer, achievement of a pregnancy, live birth delivery, and perinatal outcomes, e.g. low birthweight, multiple gestations). What is currently known in the field of lifestyle habits and IVF? There is compelling evidence that smoking has a negative influence on IVF outcomes, whereas for stress, the evidence is suggestive but insufficient due to the heterogeneity of studies. The evidence for the effects of alcohol and caffeine on IVF is inadequate, and therefore unknown, due to the scarcity of studies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Moreover, evidence shows that smoking reduces the success of fertility treatments such as IVF and ICSI (Klonoff-Cohen 2005, Mínguez-Alarcón 2018, Practice Committee 2018, Waylen 2008).”
From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Klonoff-Cohen 2005
Citations
Cites
Clinical Epidemiology: A Basic Science for Clinical Medicine.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-825_9 · Cited by 3,497
Conception to ongoing pregnancy: the 'black box' of early pregnancy loss
Macklon, N. (2002) · Human Reproduction Update · doi:10.1093/humupd/8.4.333 · Cited by 800
Smoking and female infertility: a systematic review and meta-analysis
Augood, C., Duckitt, K., & Templeton, A. A. (1998) · Human Reproduction · doi:10.1093/humrep/13.6.1532 · Cited by 510
Klonoff-Cohen, H. S., Chu, E., Natarajan, L., & Sieber, W. J. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)02008-8 · Cited by 369
Self-citationClinical management of low ovarian response to stimulation for IVF: a systematic review
Tarlatzis, B. C. (2003) · Human Reproduction Update · doi:10.1093/humupd/dmg007 · Cited by 364
Psychological evaluation and support in a program of in vitro fertilization and embryo transfer
Freeman, E. W., Boxer, A. S., Rickels, K., Tureck, R., & Mastroianni, L. (1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48316-0 · Cited by 319
Women's experience of IVF: a follow-up study
Hammarberg, K. (2001) · Human Reproduction · doi:10.1093/humrep/16.2.374 · Cited by 308
Wallach, E. E., Stillman, R. J., Rosenberg, M. J., & Sachs, B. P. (1986) · Fertility and Sterility · doi:10.1016/s0015-0282(16)49628-7 · Cited by 305
Smoking and male reproduction: a review
Vine, M. F. (1996) · International Journal of Andrology · doi:10.1111/j.1365-2605.1996.tb00523.x · Cited by 270
Smoking cigarettes is associated with increased sperm disomy in teenage men
Rubeš, J., Lowe, X. R., Moore, D. H., Perreault, S. D., Slott, V. L., Evenson, D. P., Selevan, S. G., & Wyrobek, A. J. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00261-1 · Cited by 245
Research works printed but not linked: 11
- 1989, Lancet, 1, 731
- 1989, Hum Reprod, 4, 29
- 2001, Cent Eur J Publ Hlth, 9, 64
- 1997, Fertil Steril, 68, 384
- 1995, Rom J Morphol Embryol, 41, 7
- 1978, Fertil Steril, 52, 495
- 2003, Acta Obstet Gynecol Scand, 82, 151
- 1997, Alcohol, 32, 113
- 2003, J Med Assoc Thai, 86, 425
- 2002, Nat Cell Biol, 4, s33
- 1996, Hum Reprod, 11, 95
Cited by
Sorted by citations
Homan, G. F., Davies, M., & Norman, R. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml056 · Cited by 546
“A recent review of lifestyle habits and IVF concluded that there was compelling evidence of the negative effect of smoking on IVF outcome (Klonoff-Cohen, 2005).”
BackgroundFrederiksen, Y., Farver-Vestergaard, I., Skovgård, N. G., Ingerslev, H. J., & Zachariae, R. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-006592 · Cited by 380
“Adjusted for publication bias (25)¶ – – – – – 0.”
Stress, distress and outcome of assisted reproductive technology (ART): a meta-analysis
Matthiesen, S. M. S., Frederiksen, Y., Ingerslev, H. J., & Zachariae, R. H. (2011) · Human Reproduction · doi:10.1093/humrep/der246 · Cited by 297
“…past two decades suggest that psychological stress and feelings of distress may reduce the chances of obtaining a viable pregnancy with IVF treatment (Demyttenaere et al., 1992, 1994; Thiering et al., 1993; Csemiczky et al., 2000; Kee et al., 2000; Smeenk et al., 2001, 2005; Klonoff-Cohen, 2005).”
BackgroundInfluentialLifestyle factors in people seeking infertility treatment – A review
Anderson, K. J., Nisenblat, V., & NORMAN, R. (2010) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/j.1479-828x.2009.01119.x · Cited by 275
Effects of cigarette smoking upon clinical outcomes of assisted reproduction: a meta-analysis
Waylen, A. L., Metwally, M., Jones, G. L., Wilkinson, A. J., & Ledger, W. J. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmn046 · Cited by 229
“A recent systematic review of the evidence revealed that smoking may affect rates of oocyte retrieval, IVF, embryo transfer, pregnancy and live birth delivery (Klonoff-Cohen, 2005).”
BackgroundHämmerli, K., Znoj, H., & Barth, J. (2009) · Human Reproduction Update · doi:10.1093/humupd/dmp002 · Cited by 218
“In some studies, high levels of depressive symptoms, anxiety and distress have been associated with reduced chances of becoming pregnant during ART (Demyttenaere et al., 1992, 1998; Thiering et al., 1993; Facchinetti et al., 1997; Klonoff-Cohen et al., 2001; Smeenk et al., 2001).”
BackgroundCigarette smoking and reproductive function
Soares, S. R., & de Melo, M. A. B. (2008) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e3282fc9c1e · Cited by 209
Predicting ongoing pregnancy chances after IVF and ICSI: a national prospective study
Lintsen, A. M. E., Eijkemans, M. J. C., Hunault, C. C., Bouwmans, C. A. M., Hakkaart, L., Habbema, J. D. F., & Braat, D. D. M. (2007) · Human Reproduction · doi:10.1093/humrep/dem183 · Cited by 193
“Life style like smoking, body weight and psychological factors influence the outcome of IVF (Klonoff Cohen, 2005; Lintsen et al., 2005; Smeenk et al., 2001), but are not investigated in this study.”
BackgroundEbbesen, S. M. S., Zachariae, R. H., Mehlsen, M. Y., Thomsen, D. K., Højgaard, A. D., Ottosen, L. D. M., Petersen, T., & Ingerslev, H. J. (2009) · Human Reproduction · doi:10.1093/humrep/dep185 · Cited by 186
“…maladaptive life style behaviours in terms of eating behaviours, alcohol and cigarette use) (Veenstra et al., 2007; Bacharach et al., 2008; Hooper et al., 2008; Ogden et al., 2009), and behavioural health problems are known to be associated with reduced fertilization chances (Klonoff-Cohen, 2005).”
BackgroundESHRE, O. B. O. E. A., Soini, S., Ibarreta, D., Anastasiadou, V., Aymé, S., Braga, S., Cornel, M. C., Coviello, D. A., Evers‐Kiebooms, G., Geraedts, J. P. M., et al. (2006) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201598 · Cited by 167
Psychological distress and in vitro fertilization outcome
Pasch, L. A., Gregorich, S. E., Katz, P. K., Millstein, S. G., Nachtigall, R. D., Bleil, M. E., & Adler, N. E. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.05.023 · Cited by 172
“These include nonstandardized measures, small sample sizes, cross-sectional designs, examining positive pregnancy test as the only outcome, failure to distinguish first-time IVF patients from those who had already experienced failure, and lack of control for other predictors of IVF outcomes including age, duration of…”
BackgroundAdherence to the Mediterranean diet and IVF success rate among non-obese women attempting fertility
Karayiannis, D., Kontogianni, M. D., Mendorou, C., Mastrominas, M., & Yiannakouris, N. (2018) · Human Reproduction · doi:10.1093/humrep/dey003 · Cited by 155
Should fertilization treatment start with reducing stress?
Campagne, D. M. (2006) · Human Reproduction · doi:10.1093/humrep/del078 · Cited by 154
“There is substantial evidence that personality dimensions, coping modes, stress susceptibility and resilience correlate with IVF outcome (Sanders and Bruce, 1999; Czemiczky et al., 2000; Smeenk et al., 2001; Hjelmstedt et al., 2003; Klonoff-Cohen, 2005).”
BackgroundRockliff, H., Lightman, S. L., Rhidian, E., Buchanan, H., Gordon, U. D., & Vedhara, K. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu010 · Cited by 160
“This body of literature has also been reviewed (Eugster and Vingerhoets, 1999; Boivin, 2003; Klonoff-Cohen, 2005; Verhaak et al., 2007; Haemmerli et al., 2008; Greil et al., 2009; Hammerli et al., 2009; Anderson et al., 2010; Chachamovich et al., 2010; Morreale et al., 2010; Boivin et al., 2011;…”
BackgroundCigarette smoking affects uterine receptiveness
Soares, S. R., Simón, C., Remohi, J. A., & Pellicer, A. (2006) · Human Reproduction · doi:10.1093/humrep/del394 · Cited by 135
“The same is true for MR in IVF cycles ( Klonoff-Cohen, 2005 ).”
BackgroundAn, Y., Sun, Z., Li, L., Zhang, Y., & Ji, H. (2012) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-012-9904-x · Cited by 127
Tuttle, A. M., Stämpfli, M. R., & Foster, W. G. (2009) · Human Reproduction · doi:10.1093/humrep/dep023 · Cited by 105
Peterson, B. D., Sejbaek, C. S., Pirritano, M., & Schmidt, L. (2014) · Human Reproduction · doi:10.1093/humrep/det412 · Cited by 156
“While some studies have found that depression is linked with lower pregnancy rates in couples pursuing assisted reproductive technologies (ART) (Klonoff-Cohen, 2005), two recent meta-analyses have found that depression was not associated with a reduced chance of pregnancy outcome (Boivin et al., 2011; Matthiesen et al…”
ResultInfluentialHealth and life style among infertile men and women
Revonta, M., Raitanen, J. A., Sihvo, S., Koponen, P., Klemetti, R., Männistö, S., & Luoto, R. M. (2010) · Sexual & Reproductive Healthcare · doi:10.1016/j.srhc.2010.06.002 · Cited by 88
“Smoking is also associated with male fertility [8] and it has been shown to have negative influence on IVF outcomes [2].”
BackgroundRecent cigarette smoking and assisted reproductive technologies outcome
Fuentes, A., Muñoz, A., Barnhart, K. T., Begoña Arguello, B., Díaz, M. M., & Pommer, R. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.09.073 · Cited by 88
“As in other reports (19, 20), no statistically significant association was noted between female smoking and reduced term pregnancy rate.”
ResultLintsen, A. M. E., Verhaak, C. M., Eijkemans, M. J. C., Smeenk, J. M. J., & Braat, D. D. M. (2009) · Human Reproduction · doi:10.1093/humrep/den491 · Cited by 87
Preconception lifestyle advice for people with subfertility
Anderson, K., Norman, R. J., & Middleton, P. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008189.pub2 · Cited by 85
“…and passive (secondhand) smoking of tobacco is associated with decreased fertility and reduced chance of a healthy, live birth in both the general and infertile populations (Augood 1998; Bolumar 1996; Homan 2007; Hull 2000; Klonoff-Cohen 2005; Lintsen 2005; Lumley 2009; Practice Committee 2008b).”
BackgroundObstetric Outcome in Women With Threatened Miscarriage in the First Trimester
Wijesiriwardana, A., Bhattacharya, S., Shetty, A., Smith, N. C., & Bhattacharya, S. (2006) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000199952.82151.de · Cited by 83
Hamerezaee, M., Dehghan, S. F., Golbabaei, F., Fathi, A. O.-L., Barzegar, L., & Heidarnejad, N. (2017) · Safety and Health at Work · doi:10.1016/j.shaw.2017.07.003 · Cited by 74
“For this purpose, a detailed medical history of all possible participants was obtained and then those having at least one child, not smoking [14], not placing a laptop on their legs [15], with no long-term sitting [16], with lack of varicocele [17], not using bodybuilding supplements [18], with no history of orchitis…”
MethodWu, S., Wang, M., Deng, Y. L., Qiu, J., Zhang, X., & Tan, J. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.110965 · Cited by 73
Nicoloro‐SantaBarbara, J. M., Busso, C. E., Moyer, A. E., & Lobel, M. (2018) · Social Science & Medicine · doi:10.1016/j.socscimed.2018.06.033 · Cited by 72
de Klerk, C., Hunfeld, J. A. M., Heijnen, E., Eijkemans, M. J. C., Fauser, B. C. J. M., Passchier, J., & Macklon, N. (2007) · Human Reproduction · doi:10.1093/humrep/dem357 · Cited by 71
“Although IVF treatment is known to increase stress (Verhaak et al., 2007), the evidence for an association between stress and IVF outcome is inconclusive (Eugster and Vingerhoets, 1999; Wischmann, 2003; Klonoff-Cohen, 2005).”
BackgroundWu, S., Zhang, Y., Wu, X., Hao, G., Ren, H., Qiu, J., Zhang, Y., Bi, X., Yang, A., Bai, L., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106544 · Cited by 70
Polycystic ovary syndrome, body mass index and outcomes of assisted reproductive technologies
Beydoun, H. A., Stadtmauer, L., Beydoun, M. A., Russell, H., Zhao, Y., & Oehninger, S. (2009) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60037-5 · Cited by 68
“Since 1978, over 1 million infants have been born to infertile couples through assisted reproductive technologies (Klonoff-Cohen, 2005).”
BackgroundInfluentialPreconception lifestyle advice for people with infertility
Boedt, T., Vanhove, A.-C., Vercoe, M. A., Matthys, C., Dancet, E., & Lie Fong, S. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008189.pub3 · Cited by 66
Sexual Function and Fertility Quality of Life in Women Using In Vitro Fertilization
Smith, N., Madeira, J. L., & Millard, H. R. (2015) · The Journal of Sexual Medicine · doi:10.1111/jsm.12824 · Cited by 68
Clinical factors affecting endometrial receptiveness in oocyte donation cycles
Soares, S. R., García-Velasco, J. A., Sánchez, M. F., Bosch, E., Remohi, J. A., Pellicer, A., & Simón, C. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.01.080 · Cited by 61
Qu, F., Zhang, D., Chen, L., Wang, F., Pan, J., Zhu, Y., Ma, C., Huang, Y.-T., Ye, X., Sun, S.-J., et al. (2014) · Scientific Reports · doi:10.1038/srep05028 · Cited by 57
Infertility in the light of new scientific reports – focus on male factor
Szkodziak, P. R., Woźniak, S., Czuczwar, P., Woźniakowska, E., Milart, P., Mroczkowski, A., & Paszkowski, T. (2016) · Annals of Agricultural and Environmental Medicine · doi:10.5604/12321966.1203881 · Cited by 56
“The study by Klonoff-Cohen demonstrated that caffeine consumption by men did not affect the sperm quality, or course of IVF and health of newborns [14].”
BackgroundImpact of heavy alcohol consumption and cigarette smoking on sperm DNA integrity
Amor, H., Hammadeh, M. E., Mohd, I., & Jankowski, P. M. (2022) · Andrologia · doi:10.1111/and.14434 · Cited by 52
“That suggests modifying drinking habits may increase ART outcomes (Klonoff-Cohen, 2005).”
BackgroundAlcohol, cigarette smoking, and ovarian reserve in reproductive-age African-American women
Bressler, L. H., Bernardi, L. A., Chavez, P. J. D. D., Baird, D. D., Carnethon, M. R., & Marsh, E. E. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.07.012 · Cited by 52
Aba, Y. A., Avci, D., Guzel, Y., Ozcelik, S. K., & Gurtekin, B. (2017) · Applied Nursing Research · doi:10.1016/j.apnr.2017.05.005 · Cited by 46
Chi, H.-J., Park, I.-H., Sun, H.-G., Kim, J.-W., & Lee, K.-H. (2016) · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine · doi:10.5653/cerm.2016.43.3.174 · Cited by 48
“Although the few studies that have examined the issue have been unable to confirm a perception that psychological stress may prevent a woman from attaining and maintaining a pregnancy [7,8], several studies have observed that emotional distress or stressful life events are associated with poor clinical outcomes for as…”
Carroll, K. N., Pottinger, A. M., Wynter, S., & DaCosta, V. (2019) · Andrology · doi:10.1111/andr.12670 · Cited by 47
Karimzadeh, M., Salsabili, N., Asbagh, F. A., Teymouri, R., Pourmand, G., & Naeini, T. S. (2017) · Europe PMC (PubMed Central) · Cited by 45
An, Y., Wang, Z., Ji, H., Zhang, Y., & Wu, K. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.05.092 · Cited by 44
An Overview of E-Cigarette Impact on Reproductive Health
Montjean, D., Pagé, M.-H. G., Bélanger, M., Benkhalifa, M., & Miron, P. (2023) · Life · doi:10.3390/life13030827 · Cited by 47
Why is Chromosome Segregation Error in Oocytes Increased With Maternal Aging?
Wang, Z., Schatten, H., & Sun, Q. (2011) · Physiology · doi:10.1152/physiol.00020.2011 · Cited by 45
Roberts, S., McGowan, L., Hirst, W. M., Brison, D. R., Vail, A., & Lieberman, B. A. (2010) · Health Technology Assessment · doi:10.3310/hta14380 · Cited by 40
Panagopoulou, E. P., Montgomery, A., & Tarlatzis, B. C. (2009) · Social Science & Medicine · doi:10.1016/j.socscimed.2009.06.031 · Cited by 40
“In addition, based on a recent review (Klonoff-Cohen, 2005) suggesting that distress related to infertility and its treatment should be differentiated from general distress, the study examined the effects of written emotional disclosure on both general and infertility-specific distress.”
BackgroundLifestyle factors in deteriorating male reproductive health.
Kumar, S., Kumari, A., & Murarka, S. M. (2009) · PubMed · Cited by 39
Assisted reproductive technology results: Why are live‐birth percentages so low?
Tarín, J. J., García‐Pérez, M. Á., & Cano, A. (2014) · Molecular Reproduction and Development · doi:10.1002/mrd.22340 · Cited by 37
Mosalanejad, L., & Koolee, A. K. (2013) · Europe PMC (PubMed Central) · Cited by 38
Pregnancy or Psychological Outcomes of Psychotherapy Interventions for Infertility: A Meta-Analysis
Zhou, R., Cao, Y.-M., Liu, D., & Xiao, J.-S. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.643395 · Cited by 38
“Most couples experiencing infertility will actively use ART to increase their chances of pregnancy and reduce psychological anxiety (Klonoff-Cohen, 2005; Smeenk et al., 2005).”
BackgroundPrevalence of behaviour-related fertility disorders in a clinical sample: results of a pilot study
Schilling, K., Tóth, B., Rösner, S., Strowitzki, T., & Wischmann, T. H. (2012) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-012-2436-x · Cited by 36
“Among the psychosocial risk factors that are known to be detrimental to fertility and were discussed in the literature are age, smoking and extreme overor underweight [10, 19, 20, 22].”
BackgroundMethodInfluentialKaya, Y., Beji, N. K., Aydın, Y., & Hassa, H. (2016) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.10.050 · Cited by 35
Perceptions among infertile couples of lifestyle behaviors and in vitro fertilization (IVF) success
Hawkins, L. K., Rossi, B. V., Correia, K. F. B., Lipskind, S. T., Hornstein, M. D., & Missmer, S. A. (2014) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-014-0176-5 · Cited by 34
“In vitro fertilization (IVF) and assisted reproductive technologies (ART) are resource-intensive treatments such that any contributions to success, including lifestyle modifications, are important [1].”
BackgroundManagement of male-factor infertility
Tournaye, H. J., & Cohlen, B. J. (2012) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2012.05.005 · Cited by 34
Modelling the impact of single embryo transfer in a national health service IVF programme
Roberts, S. A., Fitzgerald, C. T., & Brison, D. R. (2008) · Human Reproduction · doi:10.1093/humrep/den355 · Cited by 33
“Previous studies have demonstrated an association of smoking, as seen here, with poorer prognosis (Klonoff-Cohen, 2005).”
Result“Letting go” coping is associated with successful IVF treatment outcome
Rapoport-Hubschman, N., Gidron, Y., Reicher-Atir, R., Sapir, O., & Fisch, B. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.08.012 · Cited by 32
Preconception lifestyle advice for people with subfertility
Anderson, K. J., Norman, R. J., & Middleton, P. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008189 · Cited by 32
Antenatal moods regarding self, baby, and spouse among women who conceived by in vitro fertilization
Harf-Kashdaei, E., & Kaitz, M. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.11.035 · Cited by 32
“In all, the goals of the study were [1] to examine the ffective experience of women who conceived through IVF, ith a focus on the valence of their mood regarding self, aby, and spouse; [2] to name the content area that was most roblematic; and [3] to test for an association between omen’s affect and factors related to…”
BackgroundCheung, C. W. C., Yee, A., Chan, P.-S., Saravelos, S., Chung, J. P., Cheung, L. P., Kong, G. W. S., & Li, T. C. (2018) · Reproductive Biomedicine Online · doi:10.1016/j.rbmo.2018.04.049 · Cited by 27
Associations between ambient air pollution and IVF outcomes in a heavily polluted city in China
Liu, J., Zhao, M., Zhang, H., Zhao, J., Kong, H., Zhou, M., Guan, Y., Li, T. C., Wang, X., & Chan, D. Y. L. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.09.026 · Cited by 28
Bleil, M. E., Pasch, L. A., Gregorich, S. E., Millstein, S. G., Katz, P., & Adler, N. E. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318242096b · Cited by 28
“Although women who undergo IVF treatment report experiencing significant emotional distress (1,2), whether their psychological status affects their chances of conception remains controversial (3,4).”
BackgroundZaig, I. F., Azem, F., Schreiber, S., Litvin, Y. G., Meiboom, H., & Bloch, M. (2012) · Archives of Women s Mental Health · doi:10.1007/s00737-012-0293-z · Cited by 28
Obstetric outcome and cytokine levels in threatened miscarriage
Calleja‐Agius, J., Schembri-Wismayer, P., Calleja, N., Brincat, M., & Spiteri, D. (2010) · Gynecological Endocrinology · doi:10.3109/09513590.2010.487614 · Cited by 28
“Smoking has been linked with miscarriage in some studies [21,22].”
ResultLifestyle and Outcomes of Assisted Reproductive Techniques: A Narrative Review
Hamzehgardeshi, Z., Zohreh, S., & Gelehkolaee, K. S. (2015) · Global Journal of Health Science · doi:10.5539/gjhs.v7n5p11 · Cited by 27
“This may also cause sexual dysfunction in men and women alike, which is conducive to infertility (Klonoff-Cohen, 2005).”
BackgroundBody mass index in relation to extracellular vesicle–linked microRNAs in human follicular fluid
Martinez, R. M., Baccarelli, A., Liang, L., Dioni, L., Mansur, A., Adir, M., Bollati, V., Racowsky, C., Hauser, R. B., & Machtinger, R. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2019.04.001 · Cited by 27
Modifiable risk factors for impaired fertility in women: What nurse practitioners need to know
Kelly‐Weeder, S., & O’Connor, A. B. (2006) · Journal of the American Academy of Nurse Practitioners · doi:10.1111/j.1745-7599.2006.00130.x · Cited by 26
“In a recent systematic review of the lifestyle habits of couples undergoing IVF procedures, Klonoff-Cohen (2005) found there was insufficient evidence to determine the effect of caffeine use on IVF outcomes.”
BackgroundPeng, M., Wen, M., Jiang, T., Jiang, Y., Lv, H., Chen, T., Ling, X., Li, H., Meng, Q., Huang, B., et al. (2021) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-021-04202-9 · Cited by 25
D’Argenio, V., Dittfeld, L., Lazzeri, P., Tomaiuolo, R., & Tasciotti, E. (2021) · Genes · doi:10.3390/genes12040605 · Cited by 24
Kling, C., Schmutzler, A. G., Wilke, G., Hedderich, J., & Kabelitz, D. (2008) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-007-0538-7 · Cited by 24
“Notably, lifestyle factors like smoking and female obesity have been shown to impair the chances to conceive [11, 26] and with some support can actively be modiWed by the patients themselves.”
BackgroundSperm DNA Fragmentation: Origin and Impact on Human Reproduction
Henkel, R., & Franken, D. (2011) · Journal of Reproductive and Stem Cell Biotechnology · doi:10.1177/205891581100200204 · Cited by 17
Robinson, S., Pemberton, P., Laing, I., & Nardo, L. G. (2008) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-008-9253-y · Cited by 22
“When in vitro fertilization (IVF) is used, fewer follicles are stimulated, fewer oocytes are retrieved, implantation rates are lower, more cycles are cancelled and live birth rates are significantly lower in smokers when compared to non-smokers [5–8].”
BackgroundMedical Approaches to Ovarian Stimulation for Infertility
and, N. S. M., & Fauser, B. C. J. M. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-4907-4.00028-0 · Cited by 21
Soares, S. R., & de Melo, M. A. B. (2008) · Expert Review of Obstetrics & Gynecology · doi:10.1586/17474108.3.4.555 · Cited by 20
Ogawa, S., Ota, K., Takahashi, T., & Yoshida, H. (2023) · Nutrients · doi:10.3390/nu15173730 · Cited by 19
Survey of Japanese infertile couples' attitudes toward surrogacy
Saito, Y., & Matsuo, H. (2009) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/01674820802429435 · Cited by 19
Risk‐taking behaviours and beliefs about fertility in university students
Satılmış, İ. G., Rathfısch, G., Beji, N. K., Yarar, M., & Karamanoglu, F. (2013) · Journal of Clinical Nursing · doi:10.1111/jocn.12097 · Cited by 19
Samani, R. O., Vesali, S., Navid, B., Vakiliniya, B., & Mohammadi, M. (2017) · PubMed Central · doi:10.22074/ijfs.2017.4838 · Cited by 19
Padhy, N., Gupta, S., Mahla, A., Latha, M., & Varma, T. (2010) · Journal of Human Reproductive Sciences · doi:10.4103/0974-1208.69343 · Cited by 18
“Smoking has been proved to affect IVF outcome negatively whereas role of stress, caffeine and alcohol is inconclusive[9]”
BackgroundTherapeutic Vaccines: Hope Therapy and Its Effects on Psychiatric Symptoms among Infertile Women
Mosalanejad, L., Abdolahifard, K., & Jahromi, M. G. (2013) · Global Journal of Health Science · doi:10.5539/gjhs.v6n1p192 · Cited by 18
“Su, Tsann-Juu and Yueh-Chih Chen (2006) stated that hope was one of the main effective factors in successful IVF.”
BackgroundPietersma, C., Mulders, A. G. M. G. J., Sabanovic, A., Willemsen, S. P., Jansen, M. S., Steegers, E. A. P., Steegers‐Theunissen, R. P. M., & Rousian, M. (2022) · Human Reproduction · doi:10.1093/humrep/deac018 · Cited by 17
“Maternal smoking decreases fertilization, pregnancy and live birth rates in the IVF population (Klonoff-Cohen, 2005).”
A descriptive study of asthma in young adults conceived by IVF
Sicignano, N., Beydoun, H. A., Russell, H., Jones, H., & Oehninger, S. (2010) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2010.07.009 · Cited by 17
Screening for Psychological Conditions in Infertile Women: Provider Perspectives
Hoff, H. S., Crawford, N., & Mersereau, J. E. (2017) · Journal of Women s Health · doi:10.1089/jwh.2017.6332 · Cited by 17
Altıparmak, S., & Derya, Y. A. (2018) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2018.05.005 · Cited by 17
The Impact of Lifestyle, Diet, and Psychological Stress on Female Fertility
Vitale, S. G., Rosa, V. L. L., Petrosino, B., Rodolico, A., Mineo, L., & Laganà, A. S. (2017) · Oman Medical Journal · doi:10.5001/omj.2017.85 · Cited by 16
Tsabouri, S., Lavasidis, G., Efstathiadou, A., Papasavva, M. E., Bellou, V., Bergantini, H., Priftis, K., & Ntzani, E. (2021) · European Journal of Pediatrics · doi:10.1007/s00431-021-03975-7 · Cited by 16
“Ovulation inductionWe were able to perform a meta-analysis by combining the results of three cohort studies that examined the association between ovulation induction (by clomiphene citrate and other drugs) and childhood asthma [22, 37, 46].”
BackgroundMethodReview: Toxicants in reproductive fluid and in vitro fertilization (IVF) outcome
Kumar, S., & Mishra, V. V. (2010) · Toxicology and Industrial Health · doi:10.1177/0748233710373081 · Cited by 16
“Recently, Klonoff-Cohen (2005) mentioned the importance and efficacy of IVF by the fact that >1 106 babies have been born to infertile couples since clinical introduction of IVF in 1978.”
BackgroundInfluentialImpact of bodyweight and lifestyle on IVF outcome
Bellver, J. (2008) · Expert Review of Obstetrics & Gynecology · doi:10.1586/17474108.3.5.607 · Cited by 16
Predictors of pain during oocyte retrieval
Frederiksen, Y., Mehlsen, M. Y., Matthiesen, S. M. S., Zachariae, R. H., & Ingerslev, H. J. (2016) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/0167482x.2016.1235558 · Cited by 16
Smoking and Clinical Outcomes of Assisted Reproductive Technologies
Rockhill, K. M., Tong, V. T., Boulet, S. L., Zhang, Y., Jamieson, D. J., & Kissin, D. M. (2019) · Journal of Women s Health · doi:10.1089/jwh.2018.7293 · Cited by 16
What Are the Issues Confronting Infertile Women? A Qualitative and Quantitative Approach
Hämmerli, K., Znoj, H., & Berger, T. (2014) · The Qualitative Report · doi:10.46743/2160-3715/2010.1180 · Cited by 17
Klonoff-Cohen, H. S., Natarajan, L., & Klonoff, E. A. (2007) · Journal of Health Psychology · doi:10.1177/1359105307074282 · Cited by 15
“Studies have primarily focused on the stress of being infertile (Newton, Sherrard, & Glavac, 1999) and undergoing in vitro fertilization (IVF), the emotional effect of IVF treatment, treatment failure and implications for counseling women undergoing IVF (Klonoff-Cohen, 2005).”
BackgroundSelf-citationSuri, S., Dehghan, S. F., Sahlabadi, A. S., Ardakani, S. K., Moradi, N., Rahmati, M., & Tehrani, F. R. (2020) · Journal of Occupational Health · doi:10.1002/1348-9585.12173 · Cited by 15
Romano, G. A., Ravid, H., Zaig, I. F., Schreiber, S., Azem, F., Shachar, I., & Bloch, M. (2012) · Archives of Women s Mental Health · doi:10.1007/s00737-012-0299-6 · Cited by 14
“Reviews of studies dealing with this issue are also inconclusive (Wischmann 2003; Klonoff-Cohen 2005).”
BackgroundRecreational drugs and male fertility
Kulkarni, M., Hayden, C. J., & Kayes, O. J. (2014) · Trends in Urology & Men s Health · doi:10.1002/tre.414 · Cited by 14
Mohammadi, H., Golbabaei, F., Dehghan, S. F., Imani, H., Tehrani, F. R., & Ardakani, S. K. (2022) · American Journal of Men s Health · doi:10.1177/15579883221074821 · Cited by 13
Negative life events have detrimental effects on in-vitro fertlization outcome
Yılmaz, N., Kahyaoğlu, İ., İnal, H. A., Görkem, Ü., Devran, A., & Mollamahmutoğlu, L. (2015) · Human Fertility · doi:10.3109/14647273.2015.1022607 · Cited by 12
“Stress resulting from negative life events may lead to lifestyle behaviors such as smoking and drinking, or a change in eating behavior which eventually compromise fertility and reduce the chance of fertilization (Klonoff-Cohen, 2005).”
BackgroundThe impact of preconceptual diet on the outcome of reproductive treatments
Mmbaga, N., & Luk, J. (2012) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e3283530524 · Cited by 12
Predictors of treatment failure in young patients undergoing in vitro fertilization
Jacobs, M. B., Klonoff-Cohen, H. S., Agarwal, S. K., Kritz‐Silverstein, D. C., Lindsay, S. P., & Garzo, V. G. (2016) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-016-0725-1 · Cited by 12
“While a number of early clinical factors were considered in the present study, we were unable to examine lifestyle characteristics such as smoking, alcohol intake, and caffeine consumption [24, 25], or patient characteristics such as ethnicity [26].”
BackgroundSelf-citationLiu, X., Zhong, E., Li, J., Huang, C., Liu, W., Zeng, L., Song, G., Jiang, R., & Liu, Y. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s411362 · Cited by 11
Mahmoud, M. Y., Labib, K. M., Sileem, S. A., Mustafa, F. A., Hamed, W. M., El-Hamid, A. A., Saleh, D. M., Alanwar, A., Riad, A. A. M., Abbas, A. M., et al. (2021) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/0167482x.2021.1977277 · Cited by 11
Allan, H. T., Mounce, G., Crespo-Mirasol, E., & Shawe, J. (2018) · Journal of Clinical Nursing · doi:10.1111/jocn.14586 · Cited by 11
Metadata
- Authors
- Klonoff-Cohen, H.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Klonoff-Cohen, H.
- ORCID
- Klonoff-Cohen, H.
- Venue
- Human Reproduction Update
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-03-01
- Volume
- 11
- Issue
- 2
- Pages
- 180-204
- ISSN
- 1355-4786 (ISSN-L)
- 1460-2369
- OpenAlex
- W2151606477
- Cited by
- 173
- References
- 105
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 4 · 2022: 5 · 2021: 15 · 2020: 5 · 2019: 7 · 2018: 6 · 2017: 9 · 2016: 7 · 2015: 9 · 2014: 9 · 2013: 11 · 2012: 12
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Human Reproduction Update (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- in vitro fertilization, lifestyle habits, smoking, alcohol consumption, caffeine consumption, psychological stress, IVF outcomes, oocyte aspiration, fertilisation (biology), embryo transfer, live birth, perinatal outcomes, low birth weight, multiple pregnancy, male infertility, female infertility
- MeSH terms
- Abortion, Spontaneous, Alcohol Drinking, Birth Weight, Caffeine, Embryo Transfer, Female, Fertilization in Vitro, Gestational Age, Humans, Infant, Newborn, Life Style, Male, Oocytes, Pregnancy, Pregnancy, Multiple, Smoking, Stress, Psychological, Multivariate Analysis, Sample Size, Pregnancy Rate
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
