The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The Effects of Captivity on the Mammalian Gut Microbiome
Open accessAbstract
Recent studies increasingly note the effect of captivity or the built environment on the microbiome of humans and other animals. As symbiotic microbes are essential to many aspects of biology (e.g., digestive and immune functions), it is important to understand how lifestyle differences can impact the microbiome, and, consequently, the health of hosts. Animals living in captivity experience a range of changes that may influence the gut bacteria, such as diet changes, treatments, and reduced contact with other individuals, species and variable environmental substrates that act as sources of bacterial diversity. Thus far, initial results from previous studies point to a pattern of decreased bacterial diversity in captive animals. However, these studies are relatively limited in the scope of species that have been examined. Here we present a dataset that includes paired wild and captive samples from mammalian taxa across six Orders to investigate generalizable patterns of the effects captivity on mammalian gut bacteria. In comparing the wild to the captive condition, our results indicate that alpha diversity of the gut bacteria remains consistent in some mammalian hosts (bovids, giraffes, anteaters, and aardvarks), declines in the captive condition in some hosts (canids, primates, and equids), and increases in the captive condition in one host taxon (rhinoceros). Differences in gut bacterial beta diversity between the captive and wild state were observed for most of the taxa surveyed, except the even-toed ungulates (bovids and giraffes). Additionally, beta diversity variation was also strongly influenced by host taxonomic group, diet type, and gut fermentation physiology. Bacterial taxa that demonstrated larger shifts in relative abundance between the captive and wild states included members of the Firmicutes and Bacteroidetes. Overall, the patterns that we observe will inform a range of disciplines from veterinary practice to captive breeding efforts for biological conservation. Furthermore, bacterial taxa that persist in the captive state provide unique insight into symbiotic relationships with the host.
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Cites
QIIME allows analysis of high-throughput community sequencing data
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Self-citationDiet rapidly and reproducibly alters the human gut microbiome
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Self-citationHuman Genetics Shape the Gut Microbiome
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“Christensenellaceae are known to have high ‘heritability’ (Goodrich et al. 2014) and are thought to be recruited to perform beneficial functions within the gut community (Van Opstal and Bordenstein 2015, reviewed by Fischbach and Segre 2016).”
BackgroundSelf-citationDiet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans
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Self-citationDeblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns
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Self-citationDiet-induced extinctions in the gut microbiota compound over generations
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Cited by
Trevelline, B. K., Fontaine, S. S., Hartup, B. K., & Kohl, K. D. (2019) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2018.2448 · Cited by 452
Drivers of Microbiome Biodiversity: A Review of General Rules, Feces, and Ignorance
Reese, A. T., & Dunn, R. R. (2018) · mBio · doi:10.1128/mbio.01294-18 · Cited by 325
Modrackova, N., Stovicek, A., Burtscher, J., Bolechova, P., Killer, J., Domig, K. J., & Neuzil-Bunesova, V. (2021) · Scientific Reports · doi:10.1038/s41598-021-94824-y · Cited by 32
Metadata
- Authors
- McKenzie, V. J., Song, S. J., Delsuc, F., Prest, T. L., Oliverio, A. M., Korpita, T. M., Alexiev, A., Amato, K. R., Metcalf, J. L., Kowalewski, M., Avenant, N. L., Link, A., Di Fiore, A., Seguin-Orlando, A., Feh, C., Orlando, L., Mendelson, J. R., Sanders, J., & Knight, R.
- Venue
- Integrative and Comparative Biology
- Publisher
- Oxford University Press (OUP)
- Published
- 2017-08-07
- Volume
- 57
- Issue
- 4
- Pages
- 690-704
- ISSN
- 1540-7063 (ISSN-L)
- 1557-7023
- OpenAlex
- W2743115441
- Cited by
- 446
- References
- 12
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- McKenzie, V. J., Song, S. J., Delsuc, F., Prest, T. L., Oliverio, A. M., Korpita, T. M., Alexiev, A., Amato, K. R., Metcalf, J. L., Kowalewski, M., Avenant, N. L., Link, A., Di Fiore, A., Seguin-Orlando, A., Feh, C., Orlando, L., Mendelson, J. R., Sanders, J., & Knight, R. (2017). The Effects of Captivity on the Mammalian Gut Microbiome. Integrative and Comparative Biology. https://doi.org/10.1093/icb/icx090
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