The DOI matches its Crossref record.
Effect of Cigarette Smoking and Alcohol Consumption in the Aetiology of Cancer of the Oral Cavity, Pharynx and Larynx
Abstract
This study presents a comparative risk pattern for cancer of the oral cavity, pharynx and larynx, in relation to cigarette smoking and alcohol consumption based on data from case-control studies conducted in Korea Cancer Center Hospital, Seoul, Korea. The risk of cancer of the oral cavity, pharynx and larynx rose for current smokers and declined for ex-smokers. In males the odds ratios (ORs) for these sites rose with duration of smoking and number of cigarettes smoked per day. The relationship is strongest for laryngeal cancer. The risk for all sites was elevated linearly as amount and frequency of alcohol intake increased. Heavy drinkers, i.e. males who drank 90 g ethanol daily had an approximately 15-fold risk of cancer of the oral cavity, an 11-fold risk of pharyngeal cancer and an 11-fold risk of laryngeal cancer compared with non-drinkers. Alcohol drinking was a much stronger risk factor for cancer of the oral cavity than cancer of the pharynx and larynx. Alcohol was a much weaker risk factor for laryngeal cancer than cigarette smoking. Cancer of the oral cavity, pharynx and larynx also showed an interaction between smoking and alcohol, suggesting a synergistic effect.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan
Ko, Y., Huang, Y., Lee, C., Chen, M., Lin, L., & Tsai, C. (1995) · Journal of Oral Pathology & Medicine · doi:10.1111/j.1600-0714.1995.tb01132.x · Cited by 722
Brennan, J. A., Boyle, J. O., Koch, W. M., Goodman, S. N., Hruban, R. H., Eby, Y. J., Couch, M. J., Forastiere, A. A., & Sidransky, D. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503163321104 · Cited by 658
Clinical Practice Guideline: Hoarseness (Dysphonia) (Update)
Stachler, R. J., Francis, D. O., Schwartz, S. R., Damask, C. C., Digoy, G. P., Krouse, H. J., McCoy, S. J., Ouellette, D. R., Patel, R. R., Reavis, C. (. W., et al. (2018) · Otolaryngology–Head and Neck Surgery · doi:10.1177/0194599817751030 · Cited by 368
Combined effect of tobacco and alcohol on laryngeal cancer risk: a case–control study
Talamini, R., Bosetti, C., La Vecchia, C., Dal Maso, L., Levi, F., Bidoli, E., Negri, E., Pasche, C., Vaccarella, S., Barzan, L., et al. (2002) · Cancer Causes & Control · doi:10.1023/a:1021944123914 · Cited by 289
Metadata
- Authors
- CHOI, S. Y., & KAHYO, H.
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1991
- Volume
- 20
- Issue
- 4
- Pages
- 878-885
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W2127424871
- Cited by
- 166
- References
- 0
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Effect of Cigarette Smoking and Alcohol Consumption in the Aetiology of Cancer of the Oral Cavity, Pharynx and Larynx. https://app.cochat.ai/papers/10.1093/ije/20.4.878
- The paper
- CHOI, S. Y., & KAHYO, H. (1991). Effect of Cigarette Smoking and Alcohol Consumption in the Aetiology of Cancer of the Oral Cavity, Pharynx and Larynx. International Journal of Epidemiology. https://doi.org/10.1093/ije/20.4.878
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
