The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
Inflammatory markers and particulate air pollution: characterizing the pathway to disease
Abstract
BACKGROUND: Increased concentrations of particles in air have been related to changes in inflammatory markers that in turn are hypothesized in mediating the particle effects on cardiovascular disease. The present work examined this association in an elderly cohort in the Greater Boston area and addresses the relative role of particles from different sources. METHODS: The study included 710 subjects, active members of the VA Normative Aging Study cohort with measurements of blood markers. Concentrations of particle number (PN), black carbon (BC), fine particulate matter (PM(2.5)), and sulphates were measured at a central site near the examination site. RESULTS: Positive associations were found between traffic-related particles (PN and BC) and inflammatory markers, but only suggestive associations were found with exposures to PM(2.5) and sulphates. The particle effect on the inflammatory markers was greater among subjects older than 78 years and among obese. A suggestion for a greater effect of particles on inflammatory markers among GSTM1-null subjects and non-users of statin drugs was also seen. CONCLUSIONS: The findings of the study support the hypothesis that particles can induce cardiovascular disease through inflammatory pathways, suggestive of a greater toxicity of traffic-related particles.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Subjects who develop COPD, an important cause of respiratory mortality, may have weakened antioxidant defenses (Rahman et al. 1996), and PM2.5 can produce oxidative stress, in part because of lung inflammation (Dagher et al. 2005; Zeka et al. 2006).”
From Differentiating the effects of fine and coarse particles on daily mortality in Shanghai, China (2007) · cites this paper as Zeka et al. 2006
Citations
Cites
Inflammation in atherosclerosis
Libby, P. (2002) · Nature · doi:10.1038/nature01323 · Cited by 8,315
An association between air pollution and mortality in six U.S. cities
Dockery, D. W., Pope, C. A., Xu, X., Spengler, J. D., Ware, J. H., Fay, M. E., Ferris, B. G., & Speizer, F. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312093292401 · Cited by 8,018
Particulate air pollution and acute health effects
Seaton, A., Godden, D., MacNee, W., & Donaldson, K. (1995) · The Lancet · doi:10.1016/s0140-6736(95)90173-6 · Cited by 2,138
Danesh, J., Collins, R., Appleby, P. N., & Peto, R. (1998) · JAMA · doi:10.1001/jama.279.18.1477 · Cited by 2,027
Passage of inhaled particles into the blood circulation in humans
Nemmar, A., Hoet, P. H. M., Vanquickenborne, B., Dinsdale, D., Thomeer, M., Hoylaerts, M. F., Vanbilloen, H., Mortelmans, L., & Nemery, B. (2002) · Circulation · doi:10.1161/hc0402.104118 · Cited by 1,719
Effect of Statin Therapy on C-Reactive Protein Levels
Albert, M. A., Danielson, E., Rifai, N., Ridker, P. M., & for the PRINCE Investigators (2001) · JAMA · doi:10.1001/jama.286.1.64 · Cited by 1,644
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-499_7 · Cited by 1,591
Role of oxidative stress in cardiovascular diseases
Dhalla, N. S., Temsah, R. M., & Netticadan, T. (2000) · Journal of Hypertension · doi:10.1097/00004872-200018060-00002 · Cited by 1,467
Atherosclerosis is an inflammatory disease
Ross, R. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70266-8 · Cited by 1,458
Novel Risk Factors for Systemic Atherosclerosis
Ridker, P. M., Stampfer, M. J., & Rifai, N. (2001) · JAMA · doi:10.1001/jama.285.19.2481 · Cited by 1,290
Flagged first, then by citations
Research works printed but not linked: 2
- Claus A. Rapid physiological coagulation method for the determination of fibrinogen. Acta Haematol1957;17:237.
- Suwa T, Hogg JC, Quinlan KB et al. Particulate air pollution induces progression of atherosclerosis. J Am Coll Cardiol2002;39:935–42. · DOI
Cited by
Sorted by citations
Items 101–200 of 204
Gondalia, R., Holliday, K. M., Baldassari, A., Justice, A. E., Stewart, J. D., Liao, D., Yanosky, J. D., Engel, S. M., Jordahl, K. M., Bhatti, P., et al. (2020) · Environmental Health Perspectives · doi:10.1289/ehp5360 · Cited by 26
“However, they are consistent with observed inverse associations with short-duration exposure to PM2:5 in the Normative Aging Study (Zeka et al. 2006).”
BackgroundFine Particulate Matter (PM2.5) Air Pollution and Immune Status Among Women in the Seattle Area
Williams, L., Ulrich, C. M., Larson, T. V., Wener, M. H., Wood, B. L., Chen-Levy, Z., Campbell, P. T., Potter, J. D., McTiernan, A., & Roos, A. J. D. (2011) · Archives of Environmental & Occupational Health · doi:10.1080/19338244.2010.539636 · Cited by 24
Progress in research on effect of PM 2.5 on occurrence and development of atherosclerosis
Tian, M., Zhao, J., Mi, X., Wang, K., Kong, D., Mao, H., & Wang, T. (2020) · Journal of Applied Toxicology · doi:10.1002/jat.4110 · Cited by 24
Clearfield, M. B., Pearce, M., Nibbe, Y., Crotty, D. A., & Wagner, A. (2013) · Current Atherosclerosis Reports · doi:10.1007/s11883-013-0380-2 · Cited by 23
Busenkell, E., Collins, C. M., Moy, M. L., Hart, J. E., Grady, S. T., Coull, B. A., Schwartz, J. D., Koutrakis, P., & Garshick, E. (2022) · Environmental Research · doi:10.1016/j.envres.2022.112802 · Cited by 23
Air pollution and the number of daily deaths due to respiratory causes in Tehran
Karimi, B., & Shokrinezhad, B. (2020) · Atmospheric Environment · doi:10.1016/j.atmosenv.2020.118161 · Cited by 23
Chaulin, A. M., & Сергеев, А. К. (2022) · Cardiology Research · doi:10.14740/cr1366 · Cited by 22
“5 in the air determines the severity of the inflammatory response reaction and oxidative stress and positively correlates with the morbidity rate/incidence and mortality from CVDs across the population [27].”
BackgroundRen, C., Vokonas, P., Suh, H. H., Fang, S. C., Christiani, D. C., & Schwartz, J. D. (2010) · Environmental Health · doi:10.1186/1476-069x-9-78 · Cited by 21
“Several studies have examined effect modification and found that people carrying variants of oxidative stressrelated genes are differentially susceptible to air [12-14,16,48].”
BackgroundHuang, K., Yu, D., Fang, H., Ju, L., Piao, W., Guo, Q., Xu, X., Wei, X., Yang, Y., & Zhao, L. (2023) · Environmental Health · doi:10.1186/s12940-023-01000-y · Cited by 20
“Numerous biological pathways may be involved in the negative impact of ambient PM 2.5 on BP [11], including oxidative stress and inflammatory response [12].”
BackgroundInfluentialChiu, Y.-H. M., Garshick, E., Hart, J. E., Spiegelman, D. L., Dockery, D. W., Smith, T. J., & Laden, F. (2016) · Environmental Research · doi:10.1016/j.envres.2016.04.008 · Cited by 20
Fan, Y., Han, Y., Liu, Y. J., Wang, Y., Chen, X., Chen, W., Liang, P., Fang, Y., Wang, J., Xue, T., et al. (2020) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.0c00478 · Cited by 19
Michikawa, T., Okamura, T., Nitta, H., Nishiwaki, Y., Takebayashi, T., Ueda, K., Kadota, A., Fujiyoshi, A., Ohkubo, T., Ueshima, H., et al. (2016) · Environmental Pollution · doi:10.1016/j.envpol.2016.02.051 · Cited by 19
Hwang, J., & Kim, H. (2024) · BMC Public Health · doi:10.1186/s12889-024-18492-z · Cited by 27
“Air pollutants directly or indirectly promote a chronic inflammatory process in the human body [42, 43].”
BackgroundElvidge, T., Matthews, I. P., Gregory, C. J., & Hoogendoorn, B. (2013) · Journal of Environmental Science and Health Part C · doi:10.1080/10590501.2013.763575 · Cited by 19
“In a larger study of 710 elderly subjects over 3 years, only very marginally significant associations were found [78].”
BackgroundTracheal instillation of urban PM2.5 suspension promotes acute cardiac polarization changes in rats
Maatz, L. F., Wood, G. J. A., Rivero, D. H. R. F., & Saldiva, P. H. N. (2009) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2009000200009 · Cited by 18
Fuller, C. H., Williams, P. L., Mittleman, M. A., Patton, A. P., Spengler, J. D., & Brugge, D. (2015) · Annals of Epidemiology · doi:10.1016/j.annepidem.2015.02.003 · Cited by 17
“[26] noted that 2-day and 7-day average PNC exposure was associated with a 4% increase and 2% increase in fibrinogen, respectively.”
BackgroundResultZhang, J., Wang, Y., Feng, L., Hou, C., & Gu, Q. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-16554-y · Cited by 17
Bao, H., Dong, J., Liu, X., Tan, E., Shu, J., & Li, S. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-08797-y · Cited by 16
Kobos, L. M., & Shannahan, J. H. (2021) · Experimental Biology and Medicine · doi:10.1177/1535370220983275 · Cited by 18
“In vivo studies have demonstrated that individuals with hypertension are more prone to a variety of cardiovascular issues following PM inhalation, including depressed heart rate and blood pressure, increased WBC, and dysrhythmia.60,149–151 The increased impact of PM in such conditions has been supported by epidemiolog…”
BackgroundSH-29 and SK-119 Attenuates Air-Pollution Induced Damage by Activating Nrf2 in HaCaT Cells
Kahremany, S., Hofmann, L., Eretz-Kdosha, N., Silberstein, E., Gruzman, A., & Cohen, G. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182312371 · Cited by 14
“Other inflammatory diseases such as psoriasis, contact dermatitis, and allergic manifestations were also linked to air pollution [10,11].”
Socioeconomic Differentials in the Immediate Mortality Effects of the National Irish Smoking Ban
Stallings‐Smith, S., Goodman, P., Kabir, Z., Clancy, L., & Zeka, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098617 · Cited by 16
“and Q̂2 were the estimates for two tertiles (for example, the least and most deprived) and SÊ1 and SÊ2 were their respective standard errors [46].”
Global research trends in atherosclerosis: A bibliometric and visualized study
Tian, W., Zhang, T., Wang, X., Zhang, J., Ju, J., & Xu, H. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.956482 · Cited by 18
Particulate matter exposure and biomarkers associated with blood coagulation: A meta-analysis
Sun, M., Liang, Q., Ma, Y., Wang, F., Lin, L., Li, T., Sun, Z., & Duan, J. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111417 · Cited by 15
Ransome, Y., Slopen, N. B., Karlsson, O., & Williams, D. R. (2017) · Journal of Behavioral Medicine · doi:10.1007/s10865-017-9905-4 · Cited by 15
“Air pollution has also been associated with higher rates of cardiovascular disease (Zeka et al., 2006) through pathways of dysregulated allostatic load, which includes inflammation system markers (Clougherty & Kubzansky, 2009).”
Pearce, J. R. (2013) · Springer eBooks · doi:10.1007/978-94-007-6695-2_5 · Cited by 15
Kim, Y. C., Kim, E., Jung, J., Park, J. Y., Lee, H., Kim, D. K., Kim, Y. S., Lim, C. S., Lee, J. P., & Kim, H. (2021) · Environmental Health · doi:10.1186/s12940-021-00741-y · Cited by 14
“Research has also shown that inflammatory markers, including C-reactive protein, fibrinogen, white blood cell counts, and IL-6, are positively associated with PM exposure [22, 23], and that short-term changes in PM concentrations cause alterations in these key inflammatory biomarkers [24, 25].”
BackgroundЗайцева, Н. В., May, I. V., & Kleyn, S. V. (2013) · Health Risk Analysis · doi:10.21668/health.risk/2013.2.02 · Cited by 14
Chastang, J., Baïz, N., Parnet, L., Cadwallader, J., Frederic de, B. L. A. Y., Caillaud, D. M., Charpin, D., Dwyer, J., Lavaud, F., Rahérison, C., et al. (2017) · Pediatric Allergy and Immunology · doi:10.1111/pai.12699 · Cited by 15
“A strong increase in BMI appears to increase inflammatory mechanisms (17), and obesity may increase inflammatory responsiveness (18, 19).”
BackgroundStructural equation modeling of the inflammatory response to traffic air pollution
Baja, E. S., Schwartz, J. D., Coull, B. A., Wellenuis, G. A., Vokonas, P., & Suh, H. H. (2012) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2012.106 · Cited by 14
Kurti, S. P., Kurti, A. N., Emerson, S. R., Rosenkranz, R. R., Smith, J. R., Harms, C., & Rosenkranz, S. K. (2016) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph13070643 · Cited by 14
“Higher amounts of HAP have been reported to up-regulate oxidative [34,35] and inflammatory pathways [36].”
BackgroundHan, Y., Chatzidiakou, L., Yan, L., Chen, W., Zhang, H., Krause, A., Xue, T., Chan, Q. M., Liu, J., Wu, Y., et al. (2020) · Faraday Discussions · doi:10.1039/d0fd00097c · Cited by 13
Schiff, J. E., Vieira, C. L. Z., Garshick, E., Wang, V., Blomberg, A. J., Gold, D. R., Schwartz, J. D., Tracy, S. M., Vokonas, P., & Koutrakis, P. (2022) · PLoS ONE · doi:10.1371/journal.pone.0268700 · Cited by 13
“This is similar to those of lagged exposure of air pollutants on inflammatory and vascular markers [45].”
Seasonal distribution and modeling of diesel particulate matter in the Southeast US
Díaz‐Robles, L. A., Fu, J. S., Reed, G. D., & DeLucia, A. J. (2009) · Environment International · doi:10.1016/j.envint.2009.04.005 · Cited by 12
“A systemic marker of inflammation, c-reactive protein, is thought to be increased in production by the liver and found in higher blood concentrations in exposed individuals (Roux et al., 2006; Ruckerl et al., 2007, 2006; Sullivan et al., 2007; Zeka et al., 2006).”
BackgroundJhun, I., Kim, J.-A., Cho, B. S., Gold, D. R., Schwartz, J. D., Coull, B. A., Zanobetti, A., Rice, M. B., Mittleman, M. A., Garshick, E., et al. (2019) · Journal of the Air & Waste Management Association · doi:10.1080/10962247.2019.1596994 · Cited by 12
“Harvard investigators have found associations between BC and PN exposure and increased fibrinogen levels in the NAS cohort (Table 2, Figure 3) (Bind et al. 2012, 2014; Zeka et al. 2006).”
BackgroundPlasma nitrite is an indicator of acute changes in ambient air pollutant concentrations
Gandhi, S. K., Rich, D. Q., Ohman‐Strickland, P., Kipen, H. M., & Gow, A. J. (2014) · Inhalation Toxicology · doi:10.3109/08958378.2014.913216 · Cited by 11
“5, PM10 and O3 (Chuang et al., 2007; Eeden et al., 2012; Fang et al., 2012; Panasevich et al., 2009; Pope et al., 2004; Zeka et al., 2006).”
BackgroundSamadi, M. T., Khorsandi, H., Asl, F. B., Poorolajal, J., & Tayebinia, H. (2019) · Human and Ecological Risk Assessment An International Journal · doi:10.1080/10807039.2018.1508330 · Cited by 11
“Consistent with our results, Zeka et al. (2006) noted that exposure to ambient concentrations of traffic-source particles was associated with increased fibrinogen.”
ResultFine particulate matter and body weight status among older adults in China: Impacts and pathways
Zhang, N., Zhang, A., Wang, L., & Nie, P. (2021) · Health & Place · doi:10.1016/j.healthplace.2021.102571 · Cited by 12
Inflammation and short-term cardiopulmonary effects of particulate matter
Lotti, M., Olivato, I., & Bergamo, L. (2009) · Nanotoxicology · doi:10.1080/17435390802538763 · Cited by 10
“The pro-inflammatory effect of black carbon was stronger in GSTM1-null individuals and in those not using statins (Zeka et al. 2006).”
BackgroundResultDi, N., He, W., Zhang, K., Cui, J. T., Chen, J., Cheng, J., Chu, B., Li, S., Xie, Y., Xiang, H., et al. (2021) · Environmental Research Letters · doi:10.1088/1748-9326/abd9f3 · Cited by 9
Sousa, S., Pestana, D., Faria, G. R., Delerue-Matos, C. M., Calhau, C., & Domingues, V. F. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165015 · Cited by 9
STATE AND IMPROVEMENT OF SANITARY AND EPIDEMIOLOGICAL WELFARE MANAGEMENT IN THE RUSSIAN ARCTIC
Горбанев, С. А., Федоров, В. Н., & Андреевна, Т. Н. (2019) · Экология человека · doi:10.33396/1728-0869-2019-10-4-14 · Cited by 9
Association between particulate matter air pollution and heart attacks in San Diego County
Khanum, S., Chowdhury, Z., & Sant, K. E. (2021) · Journal of the Air & Waste Management Association · doi:10.1080/10962247.2021.1994053 · Cited by 9
“5 and have taken cross-functional dependency on personal characteristics such as body mass index and preexisting diseases (Brook et al. 2010; Zeka et al. 2006) into”
Eze, U. U., Eke, I. G., Anakwue, R. C., Oguejiofor, C. F., Onyejekwe, O. B., Udeani, I. J., Onunze, C. J., Obed, U. J., Eze, A. A., Anaga, A. O., et al. (2021) · Cardiovascular Toxicology · doi:10.1007/s12012-021-09693-8 · Cited by 8
Development of a new method to estimate the regional and local contributions to black carbon
Brochu, P. J., Kioumourtzoglou, M., Coull, B. A., Hopke, P. K., & Suh, H. H. (2011) · Atmospheric Environment · doi:10.1016/j.atmosenv.2011.01.074 · Cited by 8
The Air Quality Influences of Vehicular Traffic Emissions
Behera, S. N., & Balasubramanian, R. (2016) · InTech eBooks · doi:10.5772/64692 · Cited by 11
Zhang, C. L., Maccarone, J., Grady, S. T., Collins, C. M., Moy, M. L., Hart, J. E., Kang, C., Coull, B. A., Schwartz, J. D., Koutrakis, P., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.171897 · Cited by 7
Rana, S., Trushna, T., Tripathi, A. K., & Tiwari, R. R. (2021) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207324666210412121226 · Cited by 7
Floss, M., Zandavalli, R. B., Leão, J. R. B., Lima, C. V., Vianna, N., Barros, E., & Saldiva, P. H. N. (2022) · Revista Brasileira de Medicina de Família e Comunidade · doi:10.5712/rbmfc17(44)3038 · Cited by 7
Environmental chemical risk factors for Type 2 diabetes: an update
Starling, A. P., & Hoppin, J. A. (2015) · Diabetes Management · doi:10.2217/dmt.15.16 · Cited by 7
Chaulin, A. M., & Сергеев, А. К. (2022) · Current Cardiology Reviews · doi:10.2174/1573403x18666220817103105 · Cited by 5
“The concentration of PM 2.5 in the air determines the severity of the inflammatory response reaction and oxidative stress and positively correlates with the morbidity rate/incidence and mortality from CVDs across the population [21].”
BackgroundInfluentialParticulate Matter and Cardiovascular Health Effects
Akeem, O., & Jesus, A. (2012) · InTech eBooks · doi:10.5772/38706 · Cited by 5
Barakat, C., Elliott, S. J., & Pengelly, D. (2013) · Journal of Environmental Protection · doi:10.4236/jep.2013.48091 · Cited by 5
“Ambient pollutants trigger the respiratory tract epithelium to produce and release inflammatory cytokines [17] and can also cause oxidative stress to other body cells leading to inflammation [18,19].”
BackgroundLawrence, J., Martins, M., Liu, M., & Koutrakis, P. (2020) · Journal of the Air and Waste Management Association · doi:10.1080/10962247.2020.1850543 · Cited by 5
Zhang, Y., Rosen, R. L., Reibman, J., & Shao, Y. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19148622 · Cited by 5
“The biological mechanisms contributing to this wide range of adverse health effects have been hypothesized to involve systemic inflammation resulting from oxidative stress [51,59,60].”
BackgroundAre we understanding the respiratory effects of traffic related airborne particles?
Forastiere, F., & Faustini, A. (2008) · Thorax · doi:10.1136/thx.2008.096073 · Cited by 5
Exposure to air pollution and cardiovascular risk in young children – a pilot project
Groner, J. A., Nicholson, L., Bauer, J. A., Huang, H., Lindstrom, M., & Root, E. D. (2024) · Pediatric Research · doi:10.1038/s41390-024-03377-z · Cited by 4
Sater, M. S., AlDehaini, D. M. B., Malalla, Z. H. A., Ali, M. E., & Giha, H. A. (2025) · Biomedicines · doi:10.3390/biomedicines13030531 · Cited by 4
“In other studies, IL6 was shown to be associated with decreased LTL [21,26,27] and, controversially, it was shown to increase TE activity in vitro; it may, therefore, maintain telomere length [28,29].”
Ambient air pollution and the fetus
Yurdakök, K. (2013) · Journal of pediatric and neonatal individualized medicine · doi:10.7363/020232 · Cited by 4
“Positive associations of CRP with air pollution in various populations including people with coronary heart diseases, healthy adults and elderly have been published previously [14-18].”
BackgroundBrain Syndemics: Cognitive Deficit, Pathways of Interaction, and the Biology of Inequality
Singer, M. C., & Singer, M. C. (2021) · Neurology and Neurobiology · doi:10.31487/j.nnb.2021.02.03 · Cited by 4
“This connection is also indicated by research showing a reduction of some of the harmful effects of air pollution is achieved through increasing intake of essential micronutrients and longchain polyunsaturated fatty acids [147, 148].”
BackgroundGenotoxic and epigenetic concerns of black carbon/soot in recent times: a systematic review
Nze-Dike, O. U., Ezealisiji, K. M., Ezejiofor, A. N., Awanye, A. M., & Dike, C. S. (2025) · Discover Applied Sciences · doi:10.1007/s42452-025-06942-1 · Cited by 3
“…development of cancer [58], significant increase in cardiovascular events due to elevation in some blood markers which inadvertently affect those with type 2 diabetes, by impairing the endothelial function [59–61] changes in C-reactive protein and fibrogen which are markers of coagulation [62, 63].”
Khushboo, Chaudhary, E., Ghosh, S., Singh, N., Knibbs, L. D., West, J. J., Kumar, A., Imam, F., & Dey, S. (2025) · Environmental Research Health · doi:10.1088/2752-5309/ae11cc · Cited by 2
“The body’s chronic inflammatory response is either directly or indirectly exacerbated by air pollution [42, 43].”
Association of bedroom particulate matter, sleep quality and next-day physical performance
Lin, X., Ji, T., Guo, R., Guo, C., Gong, P., & Lan, L. (2026) · Scientific Reports · doi:10.1038/s41598-026-37949-2 · Cited by 2
Particulate Exposure and Cardiovascular Inflammation
Wingard, C. J., Cozzi, E., Scott, M. R. V., & Lust, R. M. (2013) · Springer eBooks · doi:10.1007/978-1-4614-9044-9_5 · Cited by 2
Nath, J., Kar, M., Priyadarsini, N., Boopathy, R., Subudhi, U., & Das, T. (2025) · Air Quality Atmosphere & Health · doi:10.1007/s11869-025-01806-4 · Cited by 2
“Sometimes the particles reach the bloodstream via different mechanisms and transport pathways leading to inflammation resulting in elevated levels of C-reactive protein, fibrinogen, blood leukocytes, and plasma viscosity (Zeka et al. 2006; Griffin 2013).”
Commentary: Inflamed about ultrafine particles?
Peters, A. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl202 · Cited by 2
One mechanism underlying contrasting health-economy findings
Jacobs, I. A., Podobny, M. T., & Bilusich, D. (2007) · International Journal of Epidemiology · doi:10.1093/ije/dym123 · Cited by 2
Smith, S. S. (2013) · Brunel University Research Archive (BURA) (Brunel University London) · Cited by 2
THE ROLE OF ATMOSPHERIC AIR POLLUTION BY FINE PARTICLES IN THE PATHOGENESIS OF ATHEROSCLEROSIS
Chaulin, A. M., Сергеев, А. К., & Grigoryeva, J. (2021) · Современные проблемы науки и образования · doi:10.17513/spno.31029 · Cited by 1
Air Pollution and Ischemic Heart Disease
Peters, A. (2010) · Royal Society of Chemistry eBooks · doi:10.1039/9781849732307-00220 · Cited by 1
Wilker, E. H., & Schwartz, J. D. (2010) · Royal Society of Chemistry eBooks · doi:10.1039/9781849732307-00143 · Cited by 1
Chaulin, A. M., Aleksandrov, A., Сергеев, А. К., & Duplyakov, D. V. (2021) · Archiv Euromedica · doi:10.35630/2199-885x/2021/11/6.5 · Cited by 1
“5 concentration and the ability to cause inflammatory responses and oxidative stress, which positively correlates with disease rate and mortality rate due to CVD [6, 41].”
BackgroundKrzeszowiak, J., Pawlas, K., & Rabczenko, D. (2021) · Environmental Medicine · doi:10.26444/ms/132865 · Cited by 2
Zhang, J., Wang, Y., Feng, L., Hou, C., & Gu, Q. (2021) · Research Square · doi:10.21203/rs.3.rs-633168/v1 · Cited by 1
Williams, L. (2008) · ProQuest Demo Repository
de Oliveira, R. S., & Penteado, C. W. (2014) · JICEX
Bashawri, L., & Salama, K. F. (2015) · International Journal of Medical Science and Public Health · doi:10.5455/ijmsph.2016.1705201587
Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust
Mills, N. L., Miller, M. R., Lucking, A. J., Beveridge, J., Flint, L., Wojcieszak, A., Boere, F., Fokkens, P. H. B., Boon, N. A., Sandström, T., et al. (2011)
Kaufman, J. D., Mittleman, M. A., Peters, A., Siscovick, D. S., Smith, S. C., Diez–Roux, A. V., Holguín, F., Hong, Y., Luepker, R. V., Brook, R. D., et al. (2010)
Researchof cardiac and vascular changes with ambient PM 2.5 in diabetic individuals
Schneider, A. E., Neas, L., Graff, D. W., Herbst, M., Cascio, W. E., Schmitt, M. T., Buse, J. B., Peters, A., & Devlin, R. B. (2010)
Peters, A., Siscovick, D. S., Smith, S. C., Whitsel, L. P., Diez–Roux, A. V., Holguín, F., Hong, Y., Luepker, R. V., Brook, D., Rajagopalan, S., et al. (2012)
Cardiovascular Effects of Particulate-Matter Air Pollution: An Overview and Perspectives
Araujo, J. A., & Brook, R. D. (2010) · Royal Society of Chemistry eBooks · doi:10.1039/9781849732307-00076
Zhong, J. (2016) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
Puett, R. C., Yanosky, J. D., Mittleman, M. A., Montresor-López, J., Bell, R. A., Crume, T., Dabelea, D., Dolan, L. M., D'Agostino, R. B., Marcovina, S. M., et al. (2018) · ISEE Conference Abstracts · doi:10.1289/isesisee.2018.o02.01.01
Socioeconomic Differentials in the Immediate Mortality Effects of the National Irish Smoking Ban
Stallings‐Smith, S., Zeka, A., Goodman, P. G., Kabir, Z., & Clancy, L. (2013) · ISEE Conference Abstracts · doi:10.1289/isee.2013.o-2-30-04
Short Term Exposure to Air Pollution and Mortality in the US: A Case-Crossover AnalysisPreprint
Liu, R., Wei, Y., Qiu, X., Kosheleva, A., & Schwartz, J. D. (2021) · Research Square · doi:10.21203/rs.3.rs-1138337/v1
“5 exposure was disproportionately borne by the elderly [35, 50] and people of races other than white [51, 52].”
BackgroundEnvironmental factors in health
Tallon, L. A. (2016) · doi:10.17760/d20255933
Chaulin, A. M., & Сергеев, А. К. (2022) · Кардиология в Беларуси · doi:10.34883/pi.2022.14.4.011
Jeong, Y., Park, S., Kwon, E., Hur, Y. M., You, Y., Kim, S. J., Lee, G., Lee, K. A., Cho, G. J., Oh, M., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2270323/v1
Exploring the Effects of Local Air Pollution on Popliteal Artery Aneurysms
Leinweber, M.-E., Meisenbacher, K., Schmandra, T. C., Karl, T., Torsello, G. B., Walensi, M., Geisbüsch, P., Schmitz‐Rixen, T., Jung, G., & Hofmann, G. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13113250
“…different lung receptors or nerves, and (c) possibility of PM or particulate components (organic compounds, metals) entering the circulatory system [23–26 Although a recent publication has shown that exposure to PM 2.5 increases the diameter of the thoracic aorta in mouse models [20], the…”
BackgroundInfluentialAL-Shuraifi, R. M., & Dallalbashi, Z. I. Y. (2024) · Bionatura journal : · doi:10.21931/bj/2024.01.02.6
AL-Shuraifi, R. M., & Dallalbashi, Z. I. Y. (2024) · Bionatura journal : · doi:10.70099/bj/2024.01.02.6
“…cells in the blood samples of cattle egret (Bubulcus ibis) taken from industrial areas was higher than in blood samples taken from rural areas, and this is consistent with what was indicated by 29 , who found that lead and copper contamination led to an increase in the number of white blood cells.”
Liu, R. A., Wei, Y., Qiu, X., Kosheleva, A., & Schwartz, J. D. (2022) · Figshare · doi:10.6084/m9.figshare.21009491
Liu, R. A., Wei, Y., Qiu, X., Kosheleva, A., & Schwartz, J. D. (2022) · Figshare · doi:10.6084/m9.figshare.21009494
Liu, R. A., Wei, Y., Qiu, X., Kosheleva, A., & Schwartz, J. D. (2022) · Figshare · doi:10.6084/m9.figshare.21009503
Hwang, J., & Kim, H.-J. (2024) · Figshare · doi:10.6084/m9.figshare.25572491
Huang, K., Yu, D., Hongyun, F., Lahong, J., Piao, W., Guo, Q., Xu, X., Wei, X., Yang, Y., & Zhao, L. (2023) · Figshare · doi:10.6084/m9.figshare.23908913
Liu, R. A., Wei, Y., Qiu, X., Kosheleva, A., & Schwartz, J. D. (2022) · Figshare · doi:10.6084/m9.figshare.21009506
Liu, R. A., Wei, Y., Qiu, X., Kosheleva, A., & Schwartz, J. D. (2022) · Figshare · doi:10.6084/m9.figshare.21009500
Metadata
- Authors
- Zeka, A., Sullivan, J. R., Vokonas, P. S., Sparrow, D., & Schwartz, J.
- Affiliations
- Harvard University (US)
- Boston University (US)
- Corresponding author
- Zeka, Ariana
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-07-14
- Volume
- 35
- Issue
- 5
- Pages
- 1347-1354
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W2122623434
- Cited by
- 205
- References
- 66
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 8 · 2023: 4 · 2022: 17 · 2021: 20 · 2020: 14 · 2019: 7 · 2018: 9 · 2017: 7 · 2016: 11 · 2015: 10 · 2014: 10 · 2013: 15 · 2012: 15
- FWCI
- 5.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Physical Sciences › Earth and Planetary Sciences › Atmospheric Science › Atmospheric chemistry and aerosols
- Keywords
- particulate matter, air pollution, inflammatory markers, black carbon, PM2.5, sulfate, cardiovascular disease, older adults, obesity, GSTM1, statin use
- MeSH terms
- Adult, Aged, Aged, 80 and over, Air Pollutants, Air Pollution, Vehicle Emissions, Boston, C-Reactive Protein, Cardiovascular Diseases, Environmental Exposure, Environmental Monitoring, Humans, Male, Middle Aged, Obesity, Biomarkers, Inflammation Mediators
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
