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Cited by 371

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

The number of years lived with obesity and the risk of all-cause and cause-specific mortality

Abdullah, A., Wolfe, R., Stoelwinder, J. U., de Courten, M., Stevenson, C., Walls, H. L., Peeters, A.·2011·International Journal of Epidemiology
DOI 10.1093/ije/dyr018
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Abstract

BACKGROUND: The role of the duration of obesity as an independent risk factor for mortality has not been investigated. The aim of this study was to analyse the association between the duration of obesity and the risk of mortality. METHODS: A total of 5036 participants (aged 28-62 years) of the Framingham Cohort Study were followed up every 2 years from 1948 for up to 48 years. The association between obesity duration and all-cause and cause-specific mortality was analysed using time-dependent Cox models adjusted for body mass index. The role of biological intermediates and chronic diseases was also explored. RESULTS: The adjusted hazard ratio (HR) for mortality increased as the number of years lived with obesity increased. For those who were obese for 1-4.9, 5-14.9, 15-24.9 and ≥ 25 years of the study follow-up period, adjusted HRs for all-cause mortality were 1.51 [95% confidence interval (CI) 1.27-1.79], 1.94 (95% CI 1.71-2.20), 2.25 (95% CI 1.89-2.67) and 2.52 (95% CI 2.08-3.06), respectively, compared with those who were never obese. A dose-response relation between years of duration of obesity was also clear for all-cause, cardiovascular, cancer and other-cause mortality. For every additional 2 years of obesity, the HRs for all-cause, cardiovascular disease, cancer and other-cause mortality were 1.06 (95% CI 1.05-1.07), 1.07 (95% CI 1.05-1.08), 1.03 (95% CI 1.01-1.05) and 1.07 (95% CI 1.05-1.11), respectively. CONCLUSIONS: The number of years lived with obesity is directly associated with the risk of mortality. This needs to be taken into account when estimating its burden on mortality.

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Metadata

Authors
Abdullah, A., Wolfe, R., Stoelwinder, J. U., de Courten, M., Stevenson, C., Walls, H. L., & Peeters, A.
Venue
International Journal of Epidemiology
Publisher
Oxford University Press (OUP)
Published
2011-02-27
Volume
40
Issue
4
Pages
985-996
ISSN
  • 0300-5771 (ISSN-L)
  • 1464-3685
DOI
10.1093/ije/dyr018
OpenAlex
W2121477958
Cited by
371
References
29
FWCI
24.11
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The number of years lived with obesity and the risk of all-cause and cause-specific mortality. https://app.cochat.ai/papers/10.1093/ije/dyr018
The paper
Abdullah, A., Wolfe, R., Stoelwinder, J. U., de Courten, M., Stevenson, C., Walls, H. L., & Peeters, A. (2011). The number of years lived with obesity and the risk of all-cause and cause-specific mortality. International Journal of Epidemiology. https://doi.org/10.1093/ije/dyr018

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.