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Cited by 532

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Persistence of DNA Sequences of BK Virus and JC Virus in Normal Human Tissues and in Diseased Tissues

Chesters, P. M., Heritage, J., McCance, D. J.·1983·Journal of Infectious Diseases

Abstract

Available evidence suggests that BK virus (BKV) and JC virus (JCV) persist in the kidneys of healthy individuals after primary infection and may reactivate when the host's immune response is impaired. Data supporting this hypothesis are presented. A previous study had shown BKV to be present in the kidneys of eight (57%) of 14 subjects. In the present study, which extended the investigation to a total of 30 subjects, BKV DNA was found in the renal tissues of 10 (33%) subjects, and JCV DNA was found in the renal tissues of three (10%) subjects. The viral DNA detected appeared not to be integrated with host DNA and to be isolated in foci. Investigation of normal and diseased brain tissue, including tissue from six subjects with multiple sclerosis, failed to reveal the presence of either JCV DNA or BKV DNA.

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Metadata

Authors
Chesters, P. M., Heritage, J., & McCance, D. J.
Venue
Journal of Infectious Diseases
Published
1983-04-01
Volume
147
Issue
4
Pages
676-684
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2082046294
Cited by
532
References
11
FWCI
3.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Persistence of DNA Sequences of BK Virus and JC Virus in Normal Human Tissues and in Diseased Tissues. https://app.cochat.ai/papers/10.1093/infdis/147.4.676
The paper
Chesters, P. M., Heritage, J., & McCance, D. J. (1983). Persistence of DNA Sequences of BK Virus and JC Virus in Normal Human Tissues and in Diseased Tissues. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/147.4.676

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.