The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Acute Hepatitis B Virus Infection: Relation of Age to the Clinical Expression of Disease and Subsequent Development of the Carrier State
Abstract
Yupik Eskimos of southwestern Alaska have the highest known prevalence of hepatitis B virus infection of any general population in the United States. Prospective serological surveys of 1,280 seronegative Yupik Eskimos, performed between 1971 and 1976, identified 189 (14.8%) who developed serological evidence of hepatitis B virus infection. Twenty-six (13.8%) developed clinical hepatitis during the interval when seroconversion occurred. The proportion of patients with clinically apparent hepatitis increased with age (P less than .01), ranging from 9.5% of infections in patients who were four years of age or less to 33.3% of infections in patients who were 30 years of age or older. Twenty-five (13.3%) of the 188 individuals who were studied became chronic carriers of hepatitis B surface antigen. The risk of becoming a carrier was inversely related to the age of the patient at the time of infection (P = .02). Among patients who were four years of age or less when infected, 28.8% became chronic carriers of hepatitis B, as compared with 7.7% of those who were 30 years of age or older.
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Cites
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Snedecor, G. W., & Cochran, W. G. (1967) · Cited by 6,573
HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS
Beasley, R. P., Lin, C.-C., Hwang, L.-Y., & Chien, C.-S. (1981) · The Lancet · doi:10.1016/s0140-6736(81)90585-7 · Cited by 2,865
Palmer Beasley, R., Lin, C.-C., Wang, K.-Y., Hsieh, F.-J., Hwang, L.-Y., Stevens, C., Sun, T.-S., & Szmuness, W. (1981) · The Lancet · doi:10.1016/s0140-6736(81)90832-1 · Cited by 242
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INCIDENCE OF HEPATITIS AMONG STUDENTS AT A UNIVERSITY IN TAIWAN
Beasley, R. P., Hwang, L., Lin, C., Ko, Y.-C., & Twu, S. (1983) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113532 · Cited by 90
PREVALENCE OF HEPATITIS B IN SELECTED ALASKAN ESKIMO VILLAGES
Schreeder, M. T., Bender, T. R., McMahon, B. J., MOSER, M. R., Murphy, B. L., Sheller, M. J., Heyward, W. L., Hall, D. B., & Maynard, J. E. (1983) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113659 · Cited by 70
Self-citationPrimary hepatocellular carcinoma in alaskan natives, 1969–1979
Heyward, W. L., Lanier, A. P., Bender, T. R., Hardison, H. H., Dohan, P. H., McMahon, B. J., & Francis, D. P. (1981) · International Journal of Cancer · doi:10.1002/ijc.2910280109 · Cited by 38
Self-citationProspective study of hepatitis B in thirty-two inadvertently infected people
Rinker, J., & Galambos, J. T. (1981) · Gastroenterology · doi:10.1016/0016-5085(81)90492-3 · Cited by 28
Scott, R. M., SCHNEIDER, R. J., SNTTBHAN, R., et al. (1981) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113127 · Cited by 21
Cited by
Terrault, N. A., Lok, A. S. F., McMahon, B. J., Chang, K., Hwang, J. P., Jonas, M. M., Brown, R. S., Bzowej, N. H., & Wong, J. B. (2018) · Hepatology · doi:10.1002/hep.29800 · Cited by 4,306
Self-citationSeeger, C., & Mason, W. S. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.1.51-68.2000 · Cited by 1,451
Schillie, S., Vellozzi, C., Reingold, A., Harris, A., Haber, P., Ward, J. W., & Nelson, N. P. (2018) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr6701a1 · Cited by 815
“Infants, children aged <5 years, and immunosuppressed adults with newly acquired HBV infection typically are asymptomatic, whereas symptomatic illness is noted in 30%–50% of older children, adolescents, and adults (7,8,44,50).”
BackgroundA mathematical model to estimate global hepatitis B disease burden and vaccination impact.
Goldstein, S. T., Zhou, F., Hadler, S. C., Bell, B. P., Mast, E. E., & Margolis, H. S. (2005) · International Journal of Epidemiology · doi:10.1093/ije/dyi206 · Cited by 743
Lok, A. S. F., & McMahon, B. J. (2001) · Hepatology · doi:10.1053/jhep.2001.29401 · Cited by 709
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Metadata
- Authors
- McMahon, B. J., Alward, W. L. M., Hall, D. B., Heyward, W. L., Bender, T. R., Francis, D. P., & Maynard, J. E.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1985-04-01
- Volume
- 151
- Issue
- 4
- Pages
- 599-603
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2105585202
- Cited by
- 832
- References
- 10
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Acute Hepatitis B Virus Infection: Relation of Age to the Clinical Expression of Disease and Subsequent Development of the Carrier State. https://app.cochat.ai/papers/10.1093/infdis/151.4.599
- The paper
- McMahon, B. J., Alward, W. L. M., Hall, D. B., Heyward, W. L., Bender, T. R., Francis, D. P., & Maynard, J. E. (1985). Acute Hepatitis B Virus Infection: Relation of Age to the Clinical Expression of Disease and Subsequent Development of the Carrier State. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/151.4.599
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
