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Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

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CCR5 deficiency increases risk of symptomatic West Nile virus infection

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Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

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Cytokines and T-cell homeostasis

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Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

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An Aptamer-siRNA Chimera Suppresses HIV-1 Viral Loads and Protects from Helper CD4 + T Cell Decline in Humanized Mice

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Disseminated and sustained HIV infection in CD34 + cord blood cell-transplanted Rag2 −/− γ c −/− mice

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Hematopoietic stem cell–engrafted NOD/SCID/IL2Rγnull mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

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New generation humanized mice for virus research: Comparative aspects and future prospects

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Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

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A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

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Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/−γc−/−, and C.B-17-scid/bg immunodeficient mice

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The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment

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Chemokine receptor 5 knockout strategies

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Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice

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Generation of an HIV-1-Resistant Immune System with CD34 + Hematopoietic Stem Cells Transduced with a Triple-Combination Anti-HIV Lentiviral Vector

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Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody

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Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

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Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice compared with nonhuman primates

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HIV-1 immunopathogenesis in humanized mouse models

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In Vivo Engraftment Potential of Clinical Hematopoietic Grafts

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Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis

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Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non‐obese diabetic–severe combined immunodeficient assay

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NOD/SCID repopulating cells contribute only to short-term repopulation in the baboon

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A preclinical xenotransplantation animal model to assess human hematopoietic stem cell engraftment

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RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

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Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors

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Construction of Artificial Zinc Finger Libraries and Application in Screening Zinc Finger Nucleases

Yang, H. (2012) · Xibei nongye xuebao

Structure based design of protein linkers for zinc finger nuclease

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Electronic Design and Structure Simulation of Artificial Zinc Finger Nucleases

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Using defined finger–finger interfaces as units of assembly for constructing zinc-finger nucleases

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Improved DNA binding specil finger peptides by using strir two-finger units

Moore, M. J. B., Klug, A., & Choo, Y. (2016)