Phenotypically distinct subsets of CD4 + T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

The influence of CD4+ CD25+ Foxp3+ regulatory T cells on the immune response to rotavirus infection

Kim, B., Feng, N., Narváez, C. F., He, X.-S., Eo, S. K., Lim, C. W., & Greenberg, H. B. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.07.099 · Cited by 42

Environmental influences on T regulatory cells in inflammatory bowel disease

Hardenberg, G., Steiner, T. S., & Levings, M. K. (2011) · Seminars in Immunology · doi:10.1016/j.smim.2011.01.012 · Cited by 44

Elevated serum anti-I2 and anti-OmpW antibody levels in children with IBD

Iltanen, S., Tervo, L., Halttunen, T., Wei, B., Braun, J. G., Rantala, I. S., Honkanen, T., Kronenberg, M., Cheroutre, H., Turovskaya, O., et al. (2006) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000218765.84087.42 · Cited by 42

T‐cell regulation of peripheral tolerance and immunity: the potential role for Notch signalling

Hoyne, G. F., Dallman, M. J., & Lamb, J. R. (2000) · Immunology · doi:10.1046/j.1365-2567.2000.00073.x · Cited by 42

T cells, dendritic cells and epithelial cells in intestinal homeostasis

Westendorf, A. M., Fleissner, D., Hansen, W., & Buer, J. (2009) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2009.08.009 · Cited by 43

Inflammatory Bowel Disease

Taylor, K. D., Yang, H., & Rotter, J. I. (2001) · Molecular Genetics and Metabolism · doi:10.1006/mgme.2001.3214 · Cited by 42

Expression of multiple forms of IL-1 receptor antagonist (IL-1ra) by human retinal pigment epithelial cells: identification of a new IL-1ra exon

Holtkamp, G. M., de Vos, A. F., Kijlstra, A., & Peek, R. (1999) · European Journal of Immunology · doi:10.1002/(sici)1521-4141(199901)29:01 · Cited by 31

Presence of Diabetes-Inhibiting, Glutamic Acid Decarboxylase-Specific, IL-10-Dependent, Regulatory T Cells in Naive Nonobese Diabetic Mice

You, S., Chen, C., Lee, W.-H., Brusko, T. M., Atkinson, M. A., & Liu, C. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.11.6777 · Cited by 42

Generation of Intestinal Mucosal Lymphocytes in SCID Mice Reconstituted with Mature, Thymus-Derived T Cells

Camerini, V., Sydora, B. C., Aranda, R., Nguyen, C., MacLean, C., McBride, W. H., & Kronenberg, M. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.6.2608 · Cited by 42

Phosphatidylinositol 3-Kinase γ Inhibition Ameliorates Inflammation and Tumor Growth in a Model of Colitis-Associated Cancer

González-Garcı́a, A., Sánchez-Ruíz, J., Flores, J. M., & Carrera, A. C. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.12.001 · Cited by 41

T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis

Zimmermann, J., Kühl, A. A., Weber, M., Grün, J. R., Löffler, J., Haftmann, C., Riedel, R., Maschmeyer, P., Lehmann, K., Westendorf, K., et al. (2016) · Mucosal Immunology · doi:10.1038/mi.2016.5 · Cited by 41

Microbiome modulates intestinal homeostasis against inflammatory diseases

Sun, X., & Jia, Z. (2018) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2018.10.014 · Cited by 44

Clearance of Helicobacter pylori infection through immunization: the site of T cell activation contributes to vaccine efficacy

Blanchard, T. G., Eisenberg, J. C., & Matsumoto, Y. M. (2003) · Vaccine · doi:10.1016/j.vaccine.2003.11.035 · Cited by 41

Transmembrane tumor necrosis factor is a potent inducer of colitis even in the absence of its secreted form

Corazza, N., Brunner, T., Buri, C., Rihs, S., Imboden, M. A., Seibold, I., & Mueller, C. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.06.036 · Cited by 41

MHC-II-Independent CD4+ T Cells Induce Colitis in Immunodeficient RAG−/− Hosts

Trobonjača, Z., Leithäuser, F., Möller, P., Bluethmann, H., Koezuka, Y., MacDonald, H. R., & Reimann, J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.6.3804 · Cited by 41

Inhibition of cell-mediated immunity by IL4 and IL10

Powrie, F. M., & Coffman, R. L. (1993) · Research in Immunology · doi:10.1016/s0923-2494(05)80019-7 · Cited by 41

Pharmacological Evaluation of the SCID T Cell Transfer Model of Colitis: As a Model of Crohn's Disease

Holm, T. L., Poulsen, S. S., Markholst, H., & Reedtz-Runge, S. L. (2012) · International Journal of Inflammation · doi:10.1155/2012/412178 · Cited by 40

Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8αβ+ Intraepithelial Lymphocytes in a Mouse Model for Crohn’s Disease-like Ileitis

Chang, J., Ocvirk, S., Berger, E., Kisling, S., Binder, U., Skerra, A., Lee, A. S., & Haller, D. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1200166 · Cited by 40

Tumor Infiltrating Regulatory T Cells in Sporadic and Colitis-Associated Colorectal Cancer: The Red Little Riding Hood and the Wolf

Fantini, M. C., Favale, A., Onali, S., & Facciotti, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186744 · Cited by 40

A role for regulatory T cells in renal acute kidney injury

Monteiro, R. M. M., Câmara, N. O. S., Rodrigues, M. M., Tzelepis, F., Damião, M. J., Cenedeze, M. A., Teixeira, V. D. P. A., dos Reis, M. A., & Pacheco‐Silva, Á. (2009) · Transplant Immunology · doi:10.1016/j.trim.2009.02.003 · Cited by 40

Modulation of surgical fibrosis by microbial zwitterionic polysaccharides

Ruiz‐Perez, B., Chung, D. R., Sharpe, A. H., Yagita∥, H., Kalka-Moll, W. M., Sayegh, M. H., Kasper, D. L., & Tzianabos, A. O. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505688102 · Cited by 40

Understanding Immune-Microbial Homeostasis in Intestine

Elson, C. O., & Cong, Y. (2002) · Immunologic Research · doi:10.1385/ir:26:1-3:087 · Cited by 40

Regulatory T Cells Control Immune Responses through Their Non-Redundant Tissue Specific Features

Lehtimäki, S., & Lahesmaa, R. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00294 · Cited by 39

Cytokines in canine inflammatory bowel disease

Kołodziejska-Sawerska, A., Rychlik, A., Depta, A., Wdowiak, M., Nowicki, M., & Kander, M. (2013) · Polish Journal of Veterinary Sciences · doi:10.2478/pjvs-2013-0025 · Cited by 39

Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

Rogers, D., Sood, A., Wang, H., van Beek, J. J. P., Rademaker, T. J., Artusa, P., Schneider, C., Shen, C., Wong, D. C., Bhagrath, A., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.110064 · Cited by 39

Leukemic dendritic cells: potential for therapy and insights towards immune escape by leukemic blasts

Mohty, M., Olive, D., & Gaugler, B. (2002) · Leukemia · doi:10.1038/sj.leu.2402710 · Cited by 39

Protective function of sclerosing cholangitis on IBD

Bedke, T., Stumme, F., Tomczak, M., Steglich, B., Jia, R., Bohmann, S., Wittek, A., Kempski, J., Göke, E., Böttcher, M., et al. (2024) · Gut · doi:10.1136/gutjnl-2023-330856 · Cited by 38

Immunopathogenesis of inflammatory bowel diseases: functional role of T cells and T cell homing.

Zundler, S., & Neurath, M. F. (2015) · PubMed · Cited by 38

Histone deacetylases as targets in autoimmune and autoinflammatory diseases

Hamminger, P., Rîca, R., & Ellmeier, W. (2020) · Advances in immunology · doi:10.1016/bs.ai.2020.06.001 · Cited by 39

Metabolomics activity screening of T cell–induced colitis reveals anti-inflammatory metabolites

Montenegro-Burke, J. R., Kok, B. P., Guijas, C., Domingo-Almenara, X., Moon, C., Galmozzi, A., Kitamura, S., Eckmann, L., Sáez, E., Siuzdak, G. E., et al. (2021) · Science Signaling · doi:10.1126/scisignal.abf6584 · Cited by 42

Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model

Wang, S.-B., Deng, Y., Ren, J., Xiao, B., Liu, Z., & Tao, Z. (2014) · BMC Immunology · doi:10.1186/1471-2172-15-9 · Cited by 38

TUMOUR NECROSIS FACTOR AS A THERAPEUTIC TARGET IN RHEUMATOID ARTHRITIS AND OTHER CHRONIC INFLAMMATORY DISEASES: THE CLINICAL EXPERIENCE WITH INFLIXIMAB (REMICADE™)

Bondeson, J., & Maini, R. N. (2001) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2001.tb11014.x · Cited by 38

Adaptive T‐cell responses regulating oral tolerance to protein antigen

du Pré, M. F., & Samsom, J. N. (2010) · Allergy · doi:10.1111/j.1398-9995.2010.02519.x · Cited by 38

Innate lymphoid cells in organ fibrosis

Mikami, Y., Takada, Y., Hagihara, Y., & Kanai∥, T. (2018) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2018.07.002 · Cited by 39

Stepwise chromatin and transcriptional acquisition of an intraepithelial lymphocyte program

London, M., Bilate, A. M. B., Castro, T. B. R., Sujino, T., & Mucida, D. (2021) · Nature Immunology · doi:10.1038/s41590-021-00883-8 · Cited by 38

CCR9+ plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice

Mizuno, S., Kanai∥, T., Mikami, Y., Sujino, T., Ono, Y., Hayashi, A., Handa, T., Matsumoto, A., Nakamoto, N., Matsuoka, K., et al. (2012) · Immunology Letters · doi:10.1016/j.imlet.2012.05.001 · Cited by 37

Possible Protective Effect of 5-Aminosalicylic Acid on Helicobacter pylori Infection in Patients With Inflammatory Bowel Disease

Piodi, L. P., Bardella, M., Rocchia, C., Cesana, B. M., Baldassarri, A., & Quatrini, M. (2003) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200301000-00008 · Cited by 37

Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR

Saparov, A. (1999) · International Immunology · doi:10.1093/intimm/11.8.1253 · Cited by 37

IL-7 exacerbates chronic colitis with expansion of memory IL-7RhighCD4+mucosal T cells in mice

Okada, E., Yamazaki, M., Tanabe, M., Takeuchi, T., Nanno, M., Oshima, S., Okamoto, R., Tsuchiya, K., Nakamura, T., Kanai∥, T., et al. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00276.2004 · Cited by 37

Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

Chandra, A., Yoon, S., Michieletto, M. F., Goldman, N., Ferrari, E. K., Abedi, M., Johnson, I., Fasolino, M., Pham, K., Joannas, L. D., et al. (2023) · Immunity · doi:10.1016/j.immuni.2023.05.004 · Cited by 39

CD4+CD25+Foxp3+ Regulatory T Cells Optimize Diversity of the Conventional T Cell Repertoire during Reconstitution from Lymphopenia

Winstead, C. J., Reilly, C., Moon, J. J., Jenkins, M. K., Hamilton, S. E., Jameson, S. C., Way, S. S., & Khoruts, A. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0904076 · Cited by 36

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo

Maschmeyer, P., Petkau, G., Siracusa, F., Zimmermann, J., Zügel, F., Kühl, A. A., Lehmann, K., Schimmelpfennig, S., Weber, M., Haftmann, C., et al. (2017) · Journal of Autoimmunity · doi:10.1016/j.jaut.2017.11.005 · Cited by 36

Lactobacillus paracasei Reduces Intestinal Inflammation in Adoptive Transfer Mouse Model of Experimental Colitis

Oliveira, M., Bosco, N., Perruisseau, G., Nicolas, J., Segura-Roggero, I., Duboux, S., Briand, M., Blum, S., & Benyacoub, J. (2011) · Clinical and Developmental Immunology · doi:10.1155/2011/807483 · Cited by 42

Long-Lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis

Nemoto, Y., Kanai∥, T., Kameyama, K., Shinohara, T., Sakamoto, N., Totsuka, T., Okamoto, R., Tsuchiya, K., Nakamura, T., Sudo, T., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803684 · Cited by 36

FOXP3+T Regulatory Cell Modifications in Inflammatory Bowel Disease Patients Treated with Anti-TNF α Agents

Guidi, L., Felice, C., Procoli, A., Bonanno, G., Martinelli, E., Marzo, M., Mocci, G., Pugliese, D., Andrisani, G., Danese, S., et al. (2013) · BioMed Research International · doi:10.1155/2013/286368 · Cited by 35

A murine model of appendicitis and the impact of inflammation on appendiceal lymphocyte constituents

Ng, W., Hampartzoumian, T., Lloyd, A. R., & Grimm, M. (2007) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2007.03463.x · Cited by 35

Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease

Kanai∥, T., Nemoto, Y., Kamada, N., Totsuka, T., Hisamatsu, T., Watanabe, M., & Hibi∥, T. (2009) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e32832bc627 · Cited by 33

Transfer of CD4+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo

Powrie, F. M., Coffman, R. L., & Corrêa‐Oliveira, R. (1994) · Research in Immunology · doi:10.1016/s0923-2494(94)80198-3 · Cited by 35

Pivotal roles of interleukin-6 in transmural inflammation in murine T cell transfer colitis

Kitamura, K., Nakamoto, Y., Kaneko, S., & Mukaida, N. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0604328 · Cited by 34

Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis

Reißig, S., Tang, Y., Nikolaev, A., Gerlach, K., Wolf, C., Davari, K., Gallus, C., Masri, J., Mufazalov, I. A., Neurath, M. F., et al. (2017) · Nature Communications · doi:10.1038/ncomms15069 · Cited by 35

Anti-Interleukin-18 Therapy in Murine Models of Inflammatory Bowel Disease

Lochner, M., & Förster, I. (2002) · Pathobiology · doi:10.1159/000068149 · Cited by 35

CD25+Foxp3+ Regulatory T Cells Facilitate CD4+ T Cell Clonal Anergy Induction during the Recovery from Lymphopenia

Vanasek, T. L., Nandiwada, S. L., Jenkins, M. K., & Mueller, D. L. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.10.5880 · Cited by 34

BET bromodomain inhibition reduces maturation and enhances tolerogenic properties of human and mouse dendritic cells

Schilderink, R., Bell, M. J., Reginato, E., Patten, C., Rioja, I., Hilbers, F. W., Kabala, P. A., Reedquist, K. A., Tough, D. F., Tak, P. P., et al. (2016) · Molecular Immunology · doi:10.1016/j.molimm.2016.09.010 · Cited by 35

c-Rel Is Essential for the Development of Innate and T Cell-Induced Colitis

Wang, Y., Rickman, B. H., Poutahidis, T., Schlieper, K. A., Jackson, E. A., Erdman, S. E., Fox, J. G., & Horwitz, B. H. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.12.8118 · Cited by 34

Fyn Promotes Th17 Differentiation by Regulating the Kinetics of RORγt and Foxp3 Expression

Ueda, A., Zhou, L., & Stein, P. L. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102241 · Cited by 36

The C3H/HeJBir Mouse Model: A High Susceptibility Phenotype for Colitis

Elson, C. O., Cong, Y., & Sundberg, J. P. (2000) · International Reviews of Immunology · doi:10.3109/08830180009048390 · Cited by 34

Homeostasis of intestinal immune regulation

Annacker, O., & Powrie, F. M. (2002) · Microbes and Infection · doi:10.1016/s1286-4579(02)01574-5 · Cited by 34

Distinct Roles for CXCR6+ and CXCR6− CD4+ T Cells in the Pathogenesis of Chronic Colitis

Mandai, Y., Takahashi, D., Hase, K., Obata, Y., Furusawa, Y., Ebisawa, M., Nakagawa, T., Satô, T., Katsuno, T., Saitō, Y., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065488 · Cited by 33

Top-100 highest-cited original articles in inflammatory bowel disease

Chen, X., Yang, K., Xu, Y.-J., & Li, K. (2019) · Medicine · doi:10.1097/md.0000000000015718 · Cited by 34

Transplant Tolerance

Newell, K. A., Larsen, C. P., & Kirk, A. D. (2006) · Transplantation · doi:10.1097/01.tp.0000179149.12979.13 · Cited by 33

The emerging distinct role of TNF-receptor 2 (p80) signaling in chronic inflammatory disorders.

Holtmann, M. H., Schuchmann, M., Zeller, G. C., Galle, P. R., & Neurath, M. F. (2002) · PubMed · Cited by 33

Reprogramming the immune system

Waldmann, H. (2002) · Immunological Reviews · doi:10.1034/j.1600-065x.2002.18519.x · Cited by 33

UVB-Irradiated Dendritic Cells Induce Nonproliferating, Regulatory Type T Cells

Simon, J. C., Hara, H., Denfeld, R. W., & Martin, S. F. (2002) · Skin Pharmacology and Physiology · doi:10.1159/000064537 · Cited by 33

Transcriptional and Epigenetic Control of Regulatory T Cell Development

Kitagawa, Y., Wing, J. B., & Sakaguchi, S. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.07.011 · Cited by 32

Diet, gut microbes, and genetics in immune function: can we leverage our current knowledge to achieve better outcomes in inflammatory bowel diseases?

Leone, V., Cham, C. M., & Chang, E. B. (2014) · Current Opinion in Immunology · doi:10.1016/j.coi.2014.08.004 · Cited by 32

Chromatin organizer SATB1 is an important determinant of T‐cell differentiation

Burute, M., Gottimukkala, K., & Galande, S. (2012) · Immunology and Cell Biology · doi:10.1038/icb.2012.28 · Cited by 34

Diminution of Circulating CD4+CD25high T Cells in Naïve Crohn’s Disease

Chamouard, P., Monneaux, F., Richert, Z., Voegeli, A., Lavaux, T., Gaub, M. P., Baumann, R., Oudet, P., & Muller, S. (2008) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0590-6 · Cited by 32

CD4+ T lymphocytes mediate colitis in HLA-B27 transgenic rats monoassociated with nonpathogenic Bacteroides vulgatus

Hoentjen, F., Tonkonogy, S. L., Qian, B.-F., Liu, B., Dieleman, L. A., & Sartor, R. B. (2006) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20040 · Cited by 32

Colon lamina propria dendritic cells induce a proinflammatory cytokine response in lamina propria T cells in the SCID mouse model of colitis

Drakes, M. L., Blanchard, T. G., & Czinn, S. J. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0605342 · Cited by 32

Clinical application of human CD4+CD25+regulatory Tcells for the treatment of inflammatory bowel diseases

Kanai∥, T., & Watanabe, M. (2005) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.5.4.451 · Cited by 32

Blocking inducible co-stimulator in the absence of CD28 impairs Th1 and CD25+ regulatory T cells in murine colitis

de Jong, Y. P. (2004) · International Immunology · doi:10.1093/intimm/dxh019 · Cited by 32

Development of Colonic Adenocarcinomas in a Mouse Model of Ulcerative Colitis

Shah, S. A., Simpson, S. J., Brown, L. F., Comiskey, M., de Jong, Y. P., Allen, D., & Terhorst, C. (1998) · Inflammatory Bowel Diseases · doi:10.1097/00054725-199808000-00004 · Cited by 32

Maternal tolerance is not critically dependent on interleukin‐4

Bonney, E. A. (2001) · Immunology · doi:10.1046/j.1365-2567.2001.01239.x · Cited by 31

Immunogenicity and pathogenicity of Helicobacter infections of veterinary animals

Harbour, S. N., & SUTTON, P. R. N. (2008) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2007.12.003 · Cited by 31

Review: Mouse models of inflammatory bowel disease--insights into the mechanisms of inflammation-associated colorectal cancer.

Mladenova, D. N., & Kohonen‐Corish, M. R. J. (2012) · PubMed · Cited by 31

A Novel Role for CD4+ T Cells in the Control of Cachexia

Wang, Z., Zhao, C., Moya, R., & Davies, J. D. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.7.4676 · Cited by 31

Loss of Immunological Tolerance in Gimap5-Deficient Mice Is Associated with Loss of Foxo in CD4+ T Cells

Aksoylar, H., Lampe, K., Barnes, M. J., Plas, D. R., & Hoebe, K. H. N. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1101206 · Cited by 31

TLR2‐independent induction and regulation of chronic intestinal inflammation

Boulard, O., Asquith, M. J., Powrie, F. M., & Maloy, K. J. (2009) · European Journal of Immunology · doi:10.1002/eji.200939669 · Cited by 31

Impact of Dietary Gluten on Regulatory T Cells and Th17 Cells in BALB/c Mice

Antvorskov, J. C., Fundová, P., Buschard, K., & Funda, D. P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033315 · Cited by 31

Essential crosstalk between myeloid and lymphoid cells for development of chronic colitis in myeloid‐specific signal transducer and activator of transcription 3‐deficient mice

Reindl, W., Weiß, S., Lehr, H., & Förster, I. (2006) · Immunology · doi:10.1111/j.1365-2567.2006.02473.x · Cited by 31

CD48 Controls T-Cell and Antigen-Presenting Cell Functions in Experimental Colitis

Abadía‐Molina, A. C., Ji, H., Faubion, W. A., Julien, A., Latchman, Y. E., Yagita∥, H., Sharpe, A. H., Bhan, A. K., & Terhorst, C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.12.009 · Cited by 31

Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function

Duguet, F., Locard‐Paulet, M., Marcellin, M., Chaoui, K., Bernard, I., Andréoletti, O., Lesourne, R., Burlet‐Schiltz, O., de Peredo, A. G., & Saoudi, A. (2017) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m116.062745 · Cited by 30

Host-Directed Therapies for Parasitic Diseases

Singh, B., Varikuti, S., Halsey, G., Volpedo, G., Hamza, O., & Satoskar, A. R. (2019) · Future Medicinal Chemistry · doi:10.4155/fmc-2018-0439 · Cited by 32

Animal models of inflammatory bowel disease

Kolios, G. C. (2016) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000287 · Cited by 30

CCDC88B is required for pathogenesis of inflammatory bowel disease

Fodil, N., Moradin, N., Leung, V., Olivier, J.-F., Radovanovic, I., Jeyakumar, T., Molina, M. F., McFarquhar, A., Cayrol, R., Bozec, D., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01381-y · Cited by 30

Multiple sclerosis: a study of chemokine receptors and regulatory T cells in relation to MRI variables

Putheti, P., Morris, M. J., Stawiarz, L., Teleshova, N., Kivisäkk, P., Pashenkov, M. V., Kouwenhoven, M. C. M., Wiberg, M. K., Bronge, L. H., Huang, Y. ‐., et al. (2003) · European Journal of Neurology · doi:10.1046/j.1468-1331.2003.00638.x · Cited by 30

Regulatory T cells and the liver

Chang, K. (2005) · Hepatology · doi:10.1002/hep.20678 · Cited by 30

T cell-associated CD18 but not CD62L, ICAM-1, or PSGL-1 is required for the induction of chronic colitis

Ostanin, D. V., Furr, K. L., Pavlick, K. P., Gray, L. T., Kevil, C. G., Shukla, D., D’Souza, D., Hoffman, J. M., & Grisham, M. B. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00573.2006 · Cited by 30

Genetics of inflammatory bowel disease

Taylor, K. D., Rotter, J. I., & Huiying, Y. (2007) · Springer eBooks · doi:10.1007/0-387-25808-6_3 · Cited by 30

Regulatory T-Cells and Autoimmunity

Choileain, N. N., & Redmond, H. P. (2006) · Journal of Surgical Research · doi:10.1016/j.jss.2005.07.033 · Cited by 30

Specificity, restriction and effector mechanisms of immunoregulatory CD8 T cells

Vukmanovic‐Stejic, M., Thomas, M. J., Noble, A., & Kemeny, D. M. (2001) · Immunology · doi:10.1046/j.1365-2567.2001.01193.x · Cited by 30

Tolerance to antigen-presenting cell-depleted islet allografts is CD4 T cell dependent.

Coulombe, M., Yang, H., Wolf, L. A., & Gill, R. G. (1999) · Journal of Immunology · doi:10.4049/jimmunol.162.5.2503 · Cited by 36

Impaired Peripheral Th1 CD4+ T Cell Response to Escherichia coli Proteins in Patients with Crohn’s Disease and Ankylosing Spondylitis

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Placenta-specific 8 limits IFNγ production by CD4 T cells in vitro and promotes establishment of influenza-specific CD8 T cells in vivo

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Genomic, microbial and environmental standardization in animal experimentation limiting immunological discovery

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Regulatory T cells: back to the future.

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Development and validation of a novel IL-10 deficient cell transfer model for colitis

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DX5+NKT cells induce the death of colitis‐associated cells: involvement of programmed death ligand‐1

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Update on the Therapeutic Efficacy of Tregs in IBD

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Aronia Berry Supplementation Mitigates Inflammation in T Cell Transfer-Induced Colitis by Decreasing Oxidative Stress

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OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset.

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CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells.

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Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients

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Summary

Powrie, F. M., & Mason, D. (2013)

CD45RBHIGH CD4+ T-CELLS INDUCE A PATHOGENIC TH1 RESPONSE IN THE COLON WHEN TRANSFERRED TO C-B-17 SCID MICE WHICH IS PREVENTED BY CO-TRANSFER OF THE CD45RBLOW POPULATION

Powrie, F. M., Leach, M. W., & Coffman, R. L. (1994) · Journal of Cellular Biochemistry · Cited by 1