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Cited by 275

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report

Open access
Riddle, Mark S., Connor, Bradley A., Beeching, Nicholas J., DuPont, Herbert L., Hamer, Davidson H., Kozarsky, Phyllis, Libman, Michael, Steffen, Robert, Taylor, David, Tribble, David R., Vila, Jordi, Zanger, Philipp, Ericsson, Charles D.·2017·Journal of Travel Medicine

Abstract

BACKGROUND: : Travelers' diarrhea causes significant morbidity including some sequelae, lost travel time and opportunity cost to both travelers and countries receiving travelers. Effective prevention and treatment are needed to reduce these negative impacts. METHODS: : This critical appraisal of the literature and expert consensus guideline development effort asked several key questions related to antibiotic and non-antibiotic prophylaxis and treatment, utility of available diagnostics, impact of multi-drug resistant (MDR) colonization associated with travel and travelers' diarrhea, and how our understanding of the gastrointestinal microbiome should influence current practice and future research. Studies related to these key clinical areas were assessed for relevance and quality. Based on this critical appraisal, guidelines were developed and voted on using current standards for clinical guideline development methodology. RESULTS: : New definitions for severity of travelers' diarrhea were developed. A total of 20 graded recommendations on the topics of prophylaxis, diagnosis, therapy and follow-up were developed. In addition, three non-graded consensus-based statements were adopted. CONCLUSIONS: : Prevention and treatment of travelers' diarrhea requires action at the provider, traveler and research community levels. Strong evidence supports the effectiveness of antimicrobial therapy in most cases of moderate to severe travelers' diarrhea, while either increasing intake of fluids only or loperamide or bismuth subsalicylate may suffice for most cases of mild diarrhea. Further studies are needed to address knowledge gaps regarding optimal therapies, the individual, community and global health risks of MDR acquisition, manipulation of the microbiome in prevention and treatment and the utility of laboratory testing in returning travelers with persistent diarrhea.

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Metadata

Authors
Riddle, M. S., Connor, B. A., Beeching, N. J., DuPont, H. L., Hamer, D. H., Kozarsky, P., Libman, M., Steffen, R., Taylor, D., Tribble, D. R., Vila, J., Zanger, P., & Ericsson, C. D.
Venue
Journal of Travel Medicine
Published
2017-04-01
Volume
24
Issue
suppl_1
Pages
S63-S80
ISSN
  • 1195-1982 (ISSN-L)
  • 1708-8305
OpenAlex
W2608053762
Cited by
275
References
10
FWCI
28.51
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report. https://app.cochat.ai/papers/10.1093/jtm/tax026
The paper
Riddle, M. S., Connor, B. A., Beeching, N. J., DuPont, H. L., Hamer, D. H., Kozarsky, P., Libman, M., Steffen, R., Taylor, D., Tribble, D. R., Vila, J., Zanger, P., & Ericsson, C. D. (2017). Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report. Journal of Travel Medicine. https://doi.org/10.1093/jtm/tax026

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.