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Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides
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“For instance, G418 and NB124 can stably promote the expression of full-length p53 protein.558,559”
From Targeting p53 pathways: mechanisms, structures, and advances in therapy (2023) · cites this paper as [558]
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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
Bykov, V. J. N., Issaeva, N., Shilov, A., Hultcrantz, M., Pugacheva, E., Chumakov, P., Bergman, J., Wiman, K. G., & Selivanova, G. (2002) · Nature Medicine · doi:10.1038/nm0302-282 · Cited by 1,067
p53 isoforms can regulate p53 transcriptional activity
Bourdon, J.-C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K., & Lane, D. P. (2005) · Genes & Development · doi:10.1101/gad.1339905 · Cited by 810
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Cited by
Targeting p53 pathways: mechanisms, structures, and advances in therapy
Wang, H., Guo, M., Wei, H., & Chen, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01347-1 · Cited by 1,016
Targeting mutant p53 for efficient cancer therapy
Bykov, V. J. N., Eriksson, S. E., Bianchi, J., & Wiman, K. G. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.109 · Cited by 889
Soussi, T., & Wiman, K. G. (2015) · Cell Death & Differentiation · doi:10.1038/cdd.2015.53 · Cited by 305
Drugs Targeting p53 Mutations with FDA Approval and in Clinical Trials
Nishikawa, S., & Iwakuma, T. (2023) · Cancers · doi:10.3390/cancers15020429 · Cited by 115
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Metadata
- Authors
- Floquet, C., Deforges, J., Rousset, J.-P., & Bidou, L.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-12-10
- Volume
- 39
- Issue
- 8
- Pages
- 3350-3362
- ISSN
- 1362-4962
- 0305-1048
- Cited by
- 144
- References
- 2
- Language
- en
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- Floquet, C., Deforges, J., Rousset, J.-P., & Bidou, L. (2011). Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides. Nucleic Acids Research. https://doi.org/10.1093/nar/gkq1277
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