The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse
Open accessAbstract
Chromatin immunoprecipitation, DNase I hypersensitivity and transposase-accessibility assays combined with high-throughput sequencing enable the genome-wide study of chromatin dynamics, transcription factor binding and gene regulation. Although rapidly accumulating publicly available ChIP-seq, DNase-seq and ATAC-seq data are a valuable resource for the systematic investigation of gene regulation processes, a lack of standardized curation, quality control and analysis procedures have hindered extensive reuse of these data. To overcome this challenge, we built the Cistrome database, a collection of ChIP-seq and chromatin accessibility data (DNase-seq and ATAC-seq) published before January 1, 2016, including 13 366 human and 9953 mouse samples. All the data have been carefully curated and processed with a streamlined analysis pipeline and evaluated with comprehensive quality control metrics. We have also created a user-friendly web server for data query, exploration and visualization. The resulting Cistrome DB (Cistrome Data Browser), available online at http://cistrome.org/db, is expected to become a valuable resource for transcriptional and epigenetic regulation studies.
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Cites
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ChIP‐Atlas: a data‐mining suite powered by full integration of public ChIP‐seq data
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hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets
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Self-citationConti, D. V., Darst, B. F., Moss, L. C., Saunders, E. J., Sheng, X., Chou, A., Schumacher, F. R., Olama, A. A. A., Benlloch, S., Dadaev, T., et al. (2021) · Nature Genetics · doi:10.1038/s41588-020-00748-0 · Cited by 462
Metadata
- Authors
- Mei, S., Qin, Q., Wu, Q., Sun, H., Zheng, R., Zang, C., Zhu, M., Wu, J., Shi, X., Taing, L., Liu, T., Brown, M., Meyer, C. A., & Liu, X. S.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-10-26
- Volume
- 45
- Issue
- D1
- Pages
- D658-D662
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2544405043
- Cited by
- 586
- References
- 28
- FWCI
- 16.85
- Type
- journal article
- Language
- en
- Open access
- gold
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- Mei, S., Qin, Q., Wu, Q., Sun, H., Zheng, R., Zang, C., Zhu, M., Wu, J., Shi, X., Taing, L., Liu, T., Brown, M., Meyer, C. A., & Liu, X. S. (2017). Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse. Nucleic Acids Research. https://doi.org/10.1093/nar/gkw983
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