THE FRAMINGHAM EYE STUDY

Abstract

Kahn, H. A. (Department of Epidemiology, The Johns Hopkins U. School of Hygiene and Public Health, Baltimore, MO 21205), H. M. Leibowitz, J. P. Ganley, M. M. Kini, T. Colton, R. S. Nickerson and T. R. Dawber. The Framingham Eye Study. I. Outline and major prevalence findings. Am J Epidemiol 106:17–32, 1977. During the period 1973–1975, 2675 out of 3977 still-living members of the Framingham, Massachusetts, study population, who have been under investigation for coronary disease risk factors since 1948 and who were in 1973–1975 aged 52 to 85, were given an eye examination stressing cataract, diabetic retinopathy, macular degeneration and glaucoma. Of 2940 subjects who still lived in the local Framingham area, 2477 were examined. Local population prevalence for one or both eyes positive was: 15.5 for senile cataract, 3.1 for diabetic retinopathy, 8.8% for senile macular degeneration and 3.3% for open-angle glaucoma. The proportion of adults with poor “best” visual acuity may be much less than has been estimated by the National Health Survey and the proportion with open-angle glaucoma much more than currently suspected on the basis of foreign studies.