The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Phylogenetic evidence for recombination in dengue virus
Open accessAbstract
A split decomposition analysis of dengue (DEN) virus gene sequences revealed extensive networked evolution, indicative of recombination, among DEN-1 strains but not within serotypes DEN-2, DEN-3, or DEN-4. Within DEN-1, two viruses sampled from South America in the last 10 years were identified as recombinants. To map the breakpoints and test their statistical support, we developed a novel maximum likelihood method. In both recombinants, the breakpoints were found to be in similar positions, within the fusion peptide of the envelope protein, demonstrating that a single recombination event occurred prior to the divergence of these two strains. This is the first report of recombination in natural populations of dengue virus.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Evolutionary trees from DNA sequences: A maximum likelihood approach.
Felsenstein, J. (1981) · Journal of Molecular Evolution · doi:10.1007/bf01734359 · Cited by 14,571
Statistical tests of models of DNA substitution
Goldman, N. (1993) · Journal of Molecular Evolution · doi:10.1007/bf00166252 · Cited by 736
Cited by
Mackenzie, J. S., Gubler, D. J., & Petersen, L. R. (2004) · Nature Medicine · doi:10.1038/nm1144 · Cited by 1,314
RDP2: recombination detection and analysis from sequence alignments
Martin, D. P., Williamson, C., & Posada, D. (2005) · Bioinformatics · doi:10.1093/bioinformatics/bth490 · Cited by 963
Global Spread and Persistence of Dengue
Kyle, J. L., & Harris, E. (2008) · Annual Review of Microbiology · doi:10.1146/annurev.micro.62.081307.163005 · Cited by 916
Evolutionary aspects of recombination in RNA viruses
Worobey, M., & Holmes, E. C. (1999) · Journal of General Virology · doi:10.1099/0022-1317-80-10-2535 · Cited by 556
Self-citationUse of Whole Genome Sequence Data To Infer Baculovirus Phylogeny
Herniou, E. A., Luque, T., Chen, X., Vlak, J. M., Winstanley, D., Cory, J. S., & O'Reilly, D. R. (2001) · Journal of Virology · doi:10.1128/jvi.75.17.8117-8126.2001 · Cited by 332
Metadata
- Authors
- Holmes, E. C., Worobey, M., & Rambaut, A.
- Venue
- Molecular Biology and Evolution
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-03-01
- Volume
- 16
- Issue
- 3
- Pages
- 405-409
- ISSN
- 0737-4038 (ISSN-L)
- 1537-1719
- OpenAlex
- W2070324371
- Cited by
- 410
- References
- 2
- FWCI
- 19.42
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Phylogenetic evidence for recombination in dengue virus. https://app.cochat.ai/papers/10.1093/oxfordjournals.molbev.a026121
- The paper
- Holmes, E. C., Worobey, M., & Rambaut, A. (1999). Phylogenetic evidence for recombination in dengue virus. Molecular Biology and Evolution. https://doi.org/10.1093/oxfordjournals.molbev.a026121
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.