Evolutionary aspects of recombination in RNA viruses
Abstract
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Recombination tends to oppose these negative effects by bringing beneficial mutations into the same genome and purging deleterious mutations.
“Recombination tends to oppose these negative effects by bringing beneficial mutations into the same genome and purging deleterious mutations (Worobey and Holmes, 1999).”
From Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence (2020) · cites this paper as Worobey and Holmes, 1999
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- Authors
- Worobey, M., & Holmes, E. C.
- Affiliations
- University of Oxford (GB)
- Corresponding author
- Worobey, Michael
- Venue
- Journal of General Virology
- Publisher
- Microbiology Society
- Published
- 1999-10-01
- Volume
- 80
- Issue
- 10
- Pages
- 2535-2543
- ISSN
- 0022-1317 (ISSN-L)
- 1465-2099
- OpenAlex
- W2136511801
- Cited by
- 556
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 13 · 2023: 18 · 2022: 21 · 2021: 22 · 2020: 24 · 2019: 18 · 2018: 10 · 2017: 25 · 2016: 24 · 2015: 26 · 2014: 29 · 2013: 17 · 2012: 23
- FWCI
- 1.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of General Virology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Keywords
- RNA viruses, genetic recombination, viral evolution, recombination mechanisms
- MeSH terms
- Animals, Humans, Recombination, Genetic, RNA Viruses, Evolution, Molecular
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