The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A Putative Two Pore Channel AtTPC1 Mediates Ca2+ Flux in Arabidopsis Leaf Cells
Abstract
The gene encoding voltage-gated channel with high affinity for Ca(2+) permeation has not been cloned from plants. In the present study, we isolated a full-length cDNA encoding a putative Ca(2+ )channel (AtTPC1) from Arabidopsis. AtTPC1 has two conserved homologous domains, both of which contain six transmembrane segments (S1-S6) and a pore loop (P) between S5 and S6 in each domain, and has the highest homology with the two pore channel TPC1 recently cloned from rat. The overall structure is similar to the half of the general structure of alpha-subunits of voltage-activated Ca(2+) channels from animals. AtTPC1 rescued the Ca(2+) uptake activity of a yeast mutant cch1. Sucrose-induced luminescence, which reflects a cytosolic free Ca(2+) increase in aequorin-expressing Arabidopsis leaves, was enhanced by overexpression of AtTPC1 and suppressed by antisense expression of it. Sucrose-H(+) symporters AtSUC1 and 2, which depolarize membrane potential of cells receiving sucrose, also depressed a Ca(2+) increase by their antisense expression. These results suggest that AtTPC1 mediates a voltage-activated Ca(2+ )influx in Arabidopsis leaf cells.
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Citations
Cites
Structure and Regulation of Voltage-Gated Ca 2+ Channels
Catterall, W. A. (2000) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.16.1.521 · Cited by 2,344
Molecular Identification of a Eukaryotic, Stretch-Activated Nonselective Cation Channel
Kanzaki, M., Nagasawa, M., Kojima, I., Sato, C., Naruse, K., Sokabe, M., & Iida, H. (1999) · Science · doi:10.1126/science.285.5429.882 · Cited by 213
A Homolog of Voltage-Gated Ca 2+ Channels Stimulated by Depletion of Secretory Ca 2+ in Yeast
Locke, E. G., Bonilla, M., Liang, L., Takita, Y., & Cunningham, K. W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6686-6694.2000 · Cited by 212
Self-citationThe Saccharomyces cerevisiae CCH1 gene is involved in calcium influx and mating
Fischer, M., Schnell, N., Chattaway, J., Davies, P., Dixon, G., & Sanders, D. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)01466-x · Cited by 185 · cited 2×
“CCH1 encodes a homolog of the -subunit of animal L-type Ca channel (Fischer et al. 1997).”
Background
Cited by
WHITE, P. J. (2003) · Annals of Botany · doi:10.1093/aob/mcg164 · Cited by 2,381
McAinsh, M. R., & Pittman, J. K. (2009) · New Phytologist · doi:10.1111/j.1469-8137.2008.02682.x · Cited by 756
In the light of stomatal opening: new insights into ‘the Watergate’
Roelfsema, M. R. G., & Hedrich, R. (2005) · New Phytologist · doi:10.1111/j.1469-8137.2005.01460.x · Cited by 542
The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movement
Peiter, E., Maathuis, F. J. M., Mills, L. N., Knight, H., Pelloux, J., Hetherington, A. M., & Sanders, D. (2005) · Nature · doi:10.1038/nature03381 · Cited by 538
Hedrich, R. (2012) · Physiological Reviews · doi:10.1152/physrev.00038.2011 · Cited by 472
Metadata
- Authors
- Furuichi, T., Cunningham, K. W., & Muto, S.
- Venue
- Plant and Cell Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-09-15
- Volume
- 42
- Issue
- 9
- Pages
- 900-905
- ISSN
- 0032-0781 (ISSN-L)
- 1471-9053
- OpenAlex
- W2120740717
- Cited by
- 179
- References
- 4
- FWCI
- 10.60
- Type
- journal article
- Language
- en
- Open access
- closed
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