Arabidopsis TEOSINTE BRANCHED1-LIKE 1 Regulates Axillary Bud Outgrowth and is Homologous to Monocot TEOSINTE BRANCHED1
Abstract
Axillary bud outgrowth is controlled by developmental and environmental signals through the integrated action of hormones and other factors that probably regulate the cell cycle in the buds. While hormonal regulators have been studied extensively, less is known about downstream mechanisms regulating bud outgrowth. The TCP domain protein Teosinte Branched1 (TB1) is a putative transcriptional regulator that represses bud outgrowth in grasses. Phylogenetic analyses have indicated that three hypothetical Arabidopsis (Arabidopsis thaliana) proteins, TCP1, TCP12 and TCP18 [Teosinte Branched1-Like 1 (TBL1)], are closely related to monocot TB1 proteins. A reverse genetics approach was used to identify TBL1 and TCP12 mutants to assess the function of the hypothetical proteins. No obvious phenotype was observed in tcp12 mutants. tbl1 null mutants exhibited a non-pleiotropic hyperbranching phenotype that was due to enhanced outgrowth of primary and secondary buds. The role of TBL1 as a repressor of bud outgrowth was supported by TBL1 mRNA accumulation: abundance was high in unelongated buds, and decreased to low levels in buds that were elongating. Analyses of TBL1 expression in hormone signaling mutants with aberrant branching suggest that TBL1 acts downstream of auxin and the MAX-related hormone to coordinate bud outgrowth. The data are consistent with Arabidopsis TBL1 providing functionality similar to monocot TB1, and highlight the conservation of mechanisms regulating branching acr…
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BRC1 expression is high in dormant rosette leaf buds and low in elongating buds.
“BRC1 expression is high in dormant rosette leaf buds and low in elongating, i.e., growing buds”
From Shaping plant architecture (2015) · cites this paper as Finlayson, 2007
BRC1 is a TB1 CYCLOIDEA PCF (TCP) type transcription factor.
“BRANCHED1 (BRC1) is a TB1 CYCLOIDEA PCF (TCP) type transcription factor (Aguilar-Martinez et al., 2007; Finlayson, 2007).”
From Shaping plant architecture (2015) · cites this paper as Finlayson, 2007
Auxin seems at least partially to play a role in influencing BRC1 expression.
“Therefore, auxin seems at least partially to play a role in influencing BRC1 expression.”
From Shaping plant architecture (2015) · cites this paper as Finlayson, 2007
With respect to axillary branching, BRC1 seems to be the major regulator, while BRC2 shows comparably low expression and brc2 knockout lines exhibit weaker phenotypes compared to brc1 plants.
“With respect to axillary branching, BRC1 seems to be the major regulator, while BRC2 shows a comparably low expression and brc2 knockout lines exhibit weaker phenotypes compared to brc1 plants (Aguilar-Martinez et al., 2007; Finlayson, 2007).”
From Shaping plant architecture (2015) · cites this paper as Finlayson, 2007
A gradient of BRC1 expression exists along the apical to basal axis in rosette leaf buds of Arabidopsis grown under long day conditions.
“In addition, a gradient of BRC1 expression exists along the apical to basal axis in rosette leaf buds of Arabidopsis grown under long day conditions.”
From Shaping plant architecture (2015) · cites this paper as Finlayson, 2007
In other tissues than buds, BRC1 transcript levels are very low or non-detectable.
“In other investigated tissues than buds, BRC1 transcript levels are very low or non-detectable (Aguilar-Martinez et al., 2007; Finlayson, 2007), emphasizing its specific role in the regulation of bud outgrowth.”
From Shaping plant architecture (2015) · cites this paper as Finlayson, 2007
Cites
<i>MAX1</i> and <i>MAX2</i> control shoot lateral branching in <i>Arabidopsis</i>
Stirnberg, P., van de Sande, K., & Leyser, H. M. O. (2002) · Development · doi:10.1242/dev.129.5.1131 · Cited by 692 · see citing works
Sorefan, K., Booker, J., Haurogné, K., Goussot, M., Bainbridge, K., Foo, E., Chatfield, S., Ward, S., Beveridge, C., Rameau, C., et al. (2003) · Genes & Development · doi:10.1101/gad.256603 · Cited by 604 · see citing works
Axillary bud outgrowth: sending a message
Beveridge, C. A. (2006) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2005.11.006 · Cited by 168 · see citing works
<i>AXR1</i> Acts after Lateral Bud Formation to Inhibit Lateral Bud Growth in Arabidopsis
Stirnberg, P., Chatfield, S. P., & Leyser, H. M. O. (1999) · Plant Physiology · doi:10.1104/pp.121.3.839 · Cited by 152 · see citing works
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The Pea TCP Transcription Factor PsBRC1 Acts Downstream of Strigolactones to Control Shoot Branching
Braun, N., de Saint Germain, A., Pillot, J.-P., Boutet-Mercey, S., Dalmais, M., Antoniadi, I., Li, X., Maia-Grondard, A., Le Signor, C., Bouteiller, N., et al. (2012) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.182725 · Cited by 486 · see citing works
Strigolactone Acts Downstream of Auxin to Regulate Bud Outgrowth in Pea and Arabidopsis
Brewer, P. B., Dun, E. A., Ferguson, B. J., Rameau, C., & Beveridge, C. A. (2009) · PLANT PHYSIOLOGY · doi:10.1104/pp.108.134783 · Cited by 418 · see citing works
“…mutant plants in medium containing GR24 also led to an inhibition of shoot bud outgrowth, whereas the tbl1/brc1 mutant, which is thought to act downstream of strigolactone response (Aguilar-Martı́nez et al., 2008; Finlayson, 2008), showed no response to strigolactone treatment, as expected (Fig.”
Background<i>BRANCHED1</i> Promotes Axillary Bud Dormancy in Response to Shade in <i>Arabidopsis</i>
González-Grandío, E., Poza-Carrión, C., Sorzano, C. O. S., & Cubas, P. (2013) · The Plant Cell · doi:10.1105/tpc.112.108480 · Cited by 272 · see citing works
Strigolactones and the control of plant development: lessons from shoot branching
Waldie, T., McCulloch, H., & Leyser, O. (2014) · The Plant Journal · doi:10.1111/tpj.12488 · Cited by 242 · see citing works
Teichmann, T., & Muhr, M. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00233 · Cited by 228 · see citing works
“AguilarMartinez et al. (2007) and Finlayson (2007) described the TB1 orthologs BRANCHED1 (BRC1 = TCP18) and BRANCHED2 (BRC2 = TCP12) in the dicot species Arabidopsis.”
BackgroundInfluentialPhytochrome regulation of branching in Arabidopsis
Finlayson, S. A., Krishnareddy, S. R., Kebrom, T. H., & Casal, J. J. (2010) · Plant Physiology · doi:10.1104/pp.109.148833 · Cited by 240 · see citing works
Self-citationHormonal regulation of branching in grasses
McSteen, P. (2009) · Plant Physiology · doi:10.1104/pp.108.129056 · Cited by 193 · see citing works
Suppression of sorghum axillary bud outgrowth by shade, phyB and defoliation signalling pathways
KEBROM, T. H., BRUTNELL, T. P., & FINLAYSON, S. A. (2009) · Plant, Cell & Environment · doi:10.1111/j.1365-3040.2009.02050.x · Cited by 139 · see citing works
Self-citation
- Authors
- Finlayson, S. A.
- Affiliations
- Texas A&M University (US)
- Corresponding author
- Finlayson, S. A.
- ORCID
- Finlayson, S. A.
- Venue
- Plant and Cell Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-03-29
- Volume
- 48
- Issue
- 5
- Pages
- 667-677
- ISSN
- 0032-0781 (ISSN-L)
- 1471-9053
- OpenAlex
- W2107803280
- Cited by
- 242
- References
- 4
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 13 · 2023: 9 · 2022: 14 · 2021: 18 · 2020: 21 · 2019: 19 · 2018: 15 · 2017: 13 · 2016: 13 · 2015: 16 · 2014: 12 · 2013: 19 · 2012: 15
- FWCI
- 8.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Plant and Cell Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Keywords
- TBL1, axillary bud outgrowth, branching, auxin signaling, transcriptional repression, Arabidopsis thaliana, bud elongation
- MeSH terms
- Indoleacetic Acids, Molecular Sequence Data, Mutation, Phenotype, RNA, Messenger, Arabidopsis, Gene Expression Regulation, Plant, Gene Expression Regulation, Developmental, Plant Shoots, Arabidopsis Proteins, Flowers
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