The ABC Subfamily B Auxin Transporter AtABCB19 is Involved in the Inhibitory Effects of N-1-Naphthyphthalamic Acid on the Phototropic and Gravitropic Responses of Arabidopsis Hypocotyls
Abstract
N-1-Naphthylphthalamic acid (NPA) causes the abnormal growth and development of plants by suppressing polar auxin transport. The mechanisms underlying this inhibition, however, have remained elusive. In Arabidopsis, we show that a defect in the ABC subfamily B auxin transporter AtABCB19 suppresses the inhibitory effects of NPA on hypocotyl phototropism and gravitropism, but not on hypocotyl elongation. Expression analysis using the auxin reporter gene DR5:GUS further suggests that NPA partially inhibits the asymmetric distribution of auxin in an AtABCB19-dependent manner. These data thus suggest that AtABCB19 plays an important role in the inhibitory effects of NPA on hypocotyl tropism induced by auxin.
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Exposure to red or blue light for 4 h reduced ABCB19 levels in the hypocotyl, which inhibited auxin transport to the base of hypocotyl.
“The study showed that exposure to red or blue light for 4 h reduced ABCB19 levels in the hypocotyl, which inhibited auxin transport to the base of hypocotyl (Nagashima et al., 2008a).”
From The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants (2022) · cites this paper as Nagashima et al., 2008a
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The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants
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- Authors
- Nagashima, A., Uehara, Y., & Sakai, T.
- Affiliations
- RIKEN (JP)
- Japan Science and Technology Agency (JP)
- Venue
- Plant and Cell Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-06-11
- Volume
- 49
- Issue
- 8
- Pages
- 1250-1255
- ISSN
- 0032-0781 (ISSN-L)
- 1471-9053
- OpenAlex
- W2169553669
- Cited by
- 81
- References
- 0
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 2 · 2019: 5 · 2018: 5 · 2017: 4 · 2016: 2 · 2015: 6 · 2014: 8 · 2013: 8 · 2012: 8
- FWCI
- 7.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Plant and Cell Physiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Missouri
- Novartis Foundation
- Ministry of Education, Culture, Sports, Science and Technology
- Research Foundation for Opto-Science and Technology
- Nissan Global Foundation
- Arizona Biomedical Research Commission
- Japan Society for the Promotion of Science (18770043)
- RIKEN
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
- Keywords
- N-1-naphthylphthalamic acid, polar auxin transport, gravitropism, auxin distribution, DR5::GUS reporter, Arabidopsis thaliana, plant tropism
- MeSH terms
- Carrier Proteins, Dose-Response Relationship, Drug, Phthalimides, Arabidopsis, Gene Expression Regulation, Plant, Gravitropism, Phototropism, ATP-Binding Cassette Transporters, Hypocotyl, Arabidopsis Proteins
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