Post-COVID syndrome and suicide risk
Open accessAbstract
A significant number of coronavirus disease SARS-CoV-2 (COVID-19) patients continue to have symptoms related to COVID-19 after the acute phase of illness. This post-COVID condition is sometimes called ‘post-COVID syndrome’, ‘long COVID’ or ‘post-acute COVID-19’. Persistent psychiatric symptoms among COVID-19 survivors such as depression, anxiety, post-traumatic symptoms and cognitive impairment may be related to psychological factors and neurobiological injury. COVID-19 related neurological symptoms including anosmia, ageusia, dizziness, headache and seizures may persist for a long time after the acute COVID-19 illness. Many COVID-19 survivors experience persistent physical symptoms such as cough, fatigue, dyspnea and pain after recovering from their initial illness. There is a high probability that symptoms of psychiatric, neurological and physical illnesses, as well as inflammatory damage to the brain in individuals with post-COVID syndrome increase suicidal ideation and behavior in this patient population. COVID-19 survivors without post-COVID syndrome may also be at elevated suicide risk. Studies of suicidality in COVID-19 survivors are urgently needed and will be a new area of suicide research. An appropriate management of psychiatric, neurological and medical conditions may reduce suicide risk among COVID-19 survivors with or without post-COVID syndrome.
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- Authors
- Sher, L.
- Affiliations
- James J. Peters VA Medical Center (US)
- Corresponding author
- Sher, L
- ORCID
- Sher, L
- Venue
- QJM: An International Journal of Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2021-01-24
- Volume
- 114
- Issue
- 2
- Pages
- 95-98
- ISSN
- 0033-5622 (ISSN-L)
- 1460-2725
- 1460-2393
- PMC
- PMC7928695
- OpenAlex
- W3122566052
- Cited by
- 148
- References
- 27
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 27 · 2023: 38 · 2022: 45 · 2021: 26
- FWCI
- 16.27
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- QJM (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Keywords
- long COVID, suicide risk, suicidal ideation, COVID-19 survivors, depression, anxiety, posttraumatic stress symptoms, cognitive impairment, neurological symptoms, anosmia, ageusia, persistent physical symptoms, neuroinflammation, psychiatric comorbidity
- MeSH terms
- COVID-19, Mental Disorders, Delirium, Fatigue, Headache, Humans, Severity of Illness Index, Survivors, Suicidal Ideation
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