Soluble receptor for advanced glycation end products: a new biomarker in diagnosis and prognosis of chronic inflammatory diseases

Maillard-Lefebvre, H.; Boulanger, E.; Daroux, M.; Gaxatte, C.; Hudson, B. I.; Lambert, M.

doi:10.1093/rheumatology/kep199

Cited by 190Advanced Glycation End Products researchBiomarkers in Disease MechanismsInflammation biomarkers and pathways

The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.

Soluble receptor for advanced glycation end products: a new biomarker in diagnosis and prognosis of chronic inflammatory diseases

Maillard-Lefebvre, H., Boulanger, E., Daroux, M., Gaxatte, C., Hudson, B. I., Lambert, M.·2009·Rheumatology

DOI 10.1093/rheumatology/kep199

Open this paper in CoChat — free account

Abstract

The formation of advanced glycation end products (AGEs) is a result of the non-enzymatic reaction between sugars and free amino groups of proteins. AGEs, through interacting with their specific receptor for AGEs (RAGE), result in activation of pro-inflammatory states and are involved in numerous pathologic situations. The soluble form of RAGE (sRAGE) is able to act as a decoy to avoid interaction of RAGE with its pro-inflammatory ligands (AGEs, HMGB1, S100 proteins). sRAGE levels have been found to be decreased in chronic inflammatory diseases including atherosclerosis, diabetes, renal failure and the aging process. The use of measuring circulating sRAGEs may prove to be a valuable vascular biomarker and in this review, we describe the implications of sRAGE in inflammation and propose that this molecule may represent a future therapeutic target in chronic inflammatory diseases.

Integrity signals

Registry

Crossref · 10.1093/rheumatology/kep199

Cites

65 of 65 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Soluble forms of RAGE competitively bind AGEs, preventing their interaction with mRAGE and activation of downstream pathways including pro-inflammatory responses.
“Furthermore, the soluble forms of the RAGE competitively bind AGEs preventing their interaction with mRAGE and the activation of downstream pathways, including pro-inflammatory responses.[42,43]”
From The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction (2021) · cites this paper as [42]

Atherosclerosis--an inflammatory disease
Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725
RAGE Mediates a Novel Proinflammatory Axis
Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80801-6 · Cited by 1,864
Age-specific Incidence Rates of Myocardial Infarction and Angina in Women with Systemic Lupus Erythematosus: Comparison with the Framingham Study
Manzi, S., Meilahn, E. N., Rairie, J. E., Conte, C. G., Medsger, T. A., Jansen-McWilliams, L., D’Agostino, R. B., & Kuller, L. H. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009122 · Cited by 1,831
Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.
Neeper, M. P., Schmidt, A. M., Brett, J., Yan, S. D., Wang, F., Pan, Y., Elliston, K. O., Stern, D., & SHAW, A. R. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42138-2 · Cited by 1,545
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
Schmidt, A. M., Yan, S. D., Yan, S. F., & Stern, D. M. (2001) · Journal of Clinical Investigation · doi:10.1172/jci14002 · Cited by 1,256
Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
Park, L., Raman, K. G., Lee, K. J., Lu, Y., Ferran, L. J., Chow, W. S., Stern, D. M., & Schmidt, A. M. (1998) · Nature Medicine · doi:10.1038/2012 · Cited by 1,103
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
Wautier, M., Chappey, O., Corda, S., Stern, D. M., Schmidt, A. M., & Wautier, J. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.5.e685 · Cited by 1,088
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
Schmidt, A. M., Yan, S. D., Yan, S. F., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200114002 · Cited by 1,039
The bimodal mortality pattern of systemic lupus erythematosus
Urowitz, M. B., BOOKMAN, A. A. M., Koehler, B. E., Gordon, D. A., SMYTHE, H. A., & Ogryzlo, M. A. (1976) · The American Journal of Medicine · doi:10.1016/0002-9343(76)90431-9 · Cited by 999
Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface.
Schmidt, A. M., Vianna, M., Gerlach, M. L., Brett, J., Ryan, J., Kao, J. J., Esposito, C., Hegarty, H. M., Hurley, W. L., & Clauss, M. A. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42137-0 · Cited by 833
Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury
YONEKURA, H., YAMAMOTO, Y., SAKURAI, S., PETROVA, R. G., ABEDIN, M. J., LI, H., YASUI, K., TAKEUCHI, M., MAKITA, Z., TAKASAWA, S., et al. (2003) · Biochemical Journal · doi:10.1042/bj20021371 · Cited by 716
Advanced Maillard reaction end products are associated with Alzheimer disease pathology.
Smith, M. A., Taneda, S., Richey, P. L., Miyata, S., Yan, S. D., Stern, D., Sayre, L. M., Monnier, V. M., & Perry, G. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5710 · Cited by 715
Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry
Thornalley, P. J., Battah, S., Ahmed, N., Karachalias, N., Agalou, S., Babaei‐Jadidi, R., & Dawnay, A. (2003) · Biochemical Journal · doi:10.1042/bj20030763 · Cited by 669
The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins
Chavakis, T., Bierhaus, A., Al‐Fakhri, N., Schneider, D., Witte, S., Linn, T., Nagashima, M., Morser, J., Arnold, B., Preissner, K. T., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030800 · Cited by 583
RAGE Blockade Stabilizes Established Atherosclerosis in Diabetic Apolipoprotein E–Null Mice
Bucciarelli, L. G., Wendt, T., Qu, W., Lu, Y., Lalla, E., Rong, L., Goova, M. T., Moser, B., Kislinger, T., Lee, D. C., et al. (2002) · Circulation · doi:10.1161/01.cir.0000039325.03698.36 · Cited by 562
A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane‐bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
Raucci, A., Cugusi, S., Antonelli, A., Barabino, S. M. L., Monti, L. D., Bierhaus, A., Reiß, K., Säftig, P., & Bianchi, M. E. (2008) · The FASEB Journal · doi:10.1096/fj.08-109033 · Cited by 560
Sjöc;gren's Syndrome: Autoimmune Epithelitis
Moutsopoulos, H. Μ. (1994) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1994.1123 · Cited by 440
Protein Glycation
Wautier, J., & Schmidt, A. M. (2004) · Circulation Research · doi:10.1161/01.res.0000137876.28454.64 · Cited by 440
Blockade of Receptor for Advanced Glycation End-Products Restores Effective Wound Healing in Diabetic Mice
Goova, M. T., Li, J., Kislinger, T., Qu, W., Lu, Y., Bucciarelli, L. G., Nowygrod, S., Wolf, B. M., Caliste, X. A., Yan, S. F., et al. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)61723-3 · Cited by 432
Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex
Vlassara, H., Li, Y. M., Imani, F., Wojciechowicz, D., Yang, Z., Liu, F.-T., & Cerami, A. (1995) · Molecular Medicine · doi:10.1007/bf03401604 · Cited by 421
Rage and arthritis: The G82S polymorphism amplifies the inflammatory response
Hofmann, M. A., Drury, S., Hudson, B. I., Gleason, M. R., Qu, W., Lu, Y., Lalla, E., Chitnis, S., Monteiro, J., Stickland, M. H., et al. (2002) · Genes & Immunity · doi:10.1038/sj.gene.6363861 · Cited by 383
Self-citation
Plasma Levels of Soluble Receptor for Advanced Glycation End Products and Coronary Artery Disease in Nondiabetic Men
Falcone, C., Emanuele, E., D’Angelo, A., Buzzi, M. P., Belvito, C., Cuccia, M., & Geroldi, D. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000160342.20342.00 · Cited by 378
Identification, classification, and expression of RAGE gene splice variants
Hudson, B. I., Carter, A. M., Harja, E., Kalea, A. Z., Arriero, M., Yang, H., Grant, P. J., & Schmidt, A. M. (2007) · The FASEB Journal · doi:10.1096/fj.07-9909com · Cited by 366
Self-citation
Implication of an increased oxidative stress in the formation of advanced glycation end products in patients with end-stage renal failure
Miyata, T., Wada, Y., Cai, Z., Iida, Y., Horie, K., Yasuda, Y., Maeda, K., Kurokawa, K., & de Strihou, C. V. Y. (1997) · Kidney International · doi:10.1038/ki.1997.160 · Cited by 355
The myeloperoxidase system of human phagocytes generates Nε-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation
Anderson, M. M., Requena, J. R., Crowley, J. R., Thorpe, S. R., & Heinecke, J. W. (1999) · Journal of Clinical Investigation · doi:10.1172/jci3042 · Cited by 349
Plasma Level of Endogenous Secretory RAGE Is Associated With Components of the Metabolic Syndrome and Atherosclerosis
Koyama, H., Shoji, T., Yokoyama, H., Motoyama, K., Mori, K., Fukumoto, S., Emoto, M., Shoji, T., Tamei, H., Matsuki, H., et al. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000190660.32863.cd · Cited by 311
Etiologic Diagnosis of Ischemic Stroke Subtypes With Plasma Biomarkers
Montaner, J., Perea-Gainza, M., Delgado, P., Ribó, M., Chacón, P. M., Rosell, A., Quintana, M., Palacios, M. E., Molina, C. A., & Álvarez‐Sabín, J. (2008) · Stroke · doi:10.1161/strokeaha.107.505354 · Cited by 305
RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease
Bucciarelli, L. G., Wendt, T., Rong, L., Lalla, E., Hofmann, M. A., Goova, M. T., Taguchi, A., Yan, S. F., Yan, S. D., Stern, D. M., et al. (2002) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s00018-002-8491-x · Cited by 304
High mobility group box chromosomal protein 1: A novel proinflammatory mediator in synovitis
Kokkola, R., Sundberg, E., Ulfgren, A. ‐., Palmblad, K., Li, J., Wang, H., Ulloa, L., Yang, H., Yan, X. ‐., Furie, R., et al. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10540 · Cited by 290
Receptor for advanced glycation endproducts: a multiligand receptor magnifying cell stress in diverse pathologic settings
Stern, D. M., Yan, S. D., Yan, S. F., & Schmidt, A. M. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00160-6 · Cited by 281
Three Genes in the Human MHC Class III Region near the Junction with the Class II: Gene for Receptor of Advanced Glycosylation End Products, PBX2 Homeobox Gene and a Notch Homolog, Human Counterpart of Mouse Mammary Tumor Gene int-3
Sugaya, K., Fukagawa, T., Matsumoto, K., Mita, K., Takahashi, E., Ando, A., Inoko, H., & Ikemura, T. (1994) · Genomics · doi:10.1006/geno.1994.1517 · Cited by 242
Circulating Levels of Soluble Receptor for Advanced Glycation End Products in Alzheimer Disease and Vascular Dementia
Emanuele, E., D’Angelo, A., Tomaino, C., Binetti, G. G., Ghidoni, R., Politi, P., Bernardi, L., Maletta, R., Bruni, A. C., & Geroldi, D. (2005) · Archives of Neurology · doi:10.1001/archneur.62.11.1734 · Cited by 221
Modulation of Soluble Receptor for Advanced Glycation End Products by Angiotensin-Converting Enzyme-1 Inhibition in Diabetic Nephropathy
Forbes, J. M., Thorpe, S. R., Thallas‐Bonke, V., Pete, J., Thomas, M. C., Deemer, E. R., Bassal, S., El‐Osta, A., Long, D. M., Panagiotopoulos, S., et al. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2005010062 · Cited by 211
Advanced Glycation and Lipoxidation End Products
Miyata, T., Kurokawa, K., & de Strihou, C. V. Y. (2000) · Journal of the American Society of Nephrology · doi:10.1681/asn.v1191744 · Cited by 207
Circulating Soluble Receptor for Advanced Glycation End Products Is Inversely Associated with Glycemic Control and S100A12 Protein
Basta, G., Sironi, A. M., Lazzerini, G., Turco, S. D., Buzzigoli, E., Casolaro, A., Natali, A., Ferrannini, E., & Gastaldelli, A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2559 · Cited by 204
High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis
Pullerits, R., Jonsson, I., Verdrengh, M., Bokarewa, M. I., Andersson, U., Erlandsson-Harris, H., & Tarkowski, A. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11028 · Cited by 191
Decreased plasma levels of soluble receptor for advanced glycation end-products in patients with essential hypertension
Geroldi, D., Falcone, C., Emanuele, E., D’Angelo, A., Calcagnino, M. M., Buzzi, M. P., Scioli, G. A., & Fogari, R. (2005) · Journal of Hypertension · doi:10.1097/01.hjh.0000177535.45785.64 · Cited by 190
Accelerated diabetic glomerulopathy in galectin‐3/AGE receptor 3 knockout mice
Pugliese, G., Pricci, F., Iacobini, C., Leto, G., Amadio, L., Barsotti, P., Frigeri, L. G., Hsu, D. K., Vlassara, H., Liu, F., et al. (2001) · The FASEB Journal · doi:10.1096/fj.01-0006com · Cited by 185
Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
Yan, S. S., Wu, Z., Zhang, H. P., Furtado, G. D. C., Chen, X., Yan, S. F., Schmidt, A. M., Brown, C., Stern, A., Lafaille, J. J., et al. (2003) · Nature Medicine · doi:10.1038/nm831 · Cited by 182
Serum and mucosal S100 proteins, calprotectin (S100A8/S100A9) and S100A12, are elevated at diagnosis in children with inflammatory bowel disease
Leach, S. T., Yang, Z., Messina, I., Song, C., Geczy, C. L., Cunningham, A. M., & Day, A. S. (2007) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520701416709 · Cited by 180
Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control
Pullerits, R., Bokarewa, M. I., Dahlberg, L., & Tarkowski, A. (2005) · Arthritis Research & Therapy · doi:10.1186/ar1749 · Cited by 166
AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression
Boulanger, É., Wautier, M., Wautier, J., Boval, B., Panis, Y. H., Wernert, N., Danzé, P. M., & Dequiedt, P. (2002) · Kidney International · doi:10.1046/j.1523-1755.2002.00115.x · Cited by 162
Positive association between serum levels of advanced glycation end products and the soluble form of receptor for advanced glycation end products in nondiabetic subjects
Yamagishi, S.-I., Adachi, H., Nakamura, K., Matsui, T., Jinnouchi, Y., Takenaka, K., Takeuchi, M., Enomoto, M., Furuki, K., Hino, A., et al. (2006) · Metabolism · doi:10.1016/j.metabol.2006.05.007 · Cited by 148
Soluble RAGE in type 2 diabetes: Association with oxidative stress
Devangelio, E., Santilli, F., Formoso, G., Ferroni, P., Bucciarelli, L. G., Michetti, N., Clissa, C., Ciabattoni, G., Consoli, A., & Davı̀, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.03.015 · Cited by 147
Accelerated atherosclerosis in patients with Wegener's granulomatosis
de Leeuw, K., Sanders, J.-S., Stegeman, C. A., Smit, A. J., Kallenberg, C. G., & Bijl, M. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.029033 · Cited by 146
S100A12 (EN-RAGE) in monitoring Kawasaki disease
Foell, D., Ichida, F., Vogl, T., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12986-8 · Cited by 130
Decreased plasma soluble RAGE in patients with hypercholesterolemia: Effects of statins
Santilli, F., Bucciarelli, L. G., Noto, D., Cefalu, A. B., Davì, V., Ferrante, E., Pettinella, C., Averna, M. R., Ciabattoni, G., & Davı̀, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.06.017 · Cited by 124
Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via β2 integrin Mac‐1
Pullerits, R., Brisslert, M., Jonsson, I., & Tarkowski, A. (2006) · Arthritis & Rheumatism · doi:10.1002/art.22217 · Cited by 115
Galectin‐3/AGE‐receptor 3 knockout mice show accelerated AGE‐induced glomerular injury: evidence for a protective role of galectin‐3 as an AGE receptor
Iacobini, C., Menini, S., Oddi, G., Ricci, P. C., Amadio, L., Pricci, F., Olivieri, A., Sorcini, M., Mario, U. D., Pesce, C. M., et al. (2004) · The FASEB Journal · doi:10.1096/fj.04-2031fje · Cited by 113
RAGE: developmental expression and positive feedback regulation by Egr-1 during cigarette smoke exposure in pulmonary epithelial cells
Reynolds, P. R., Kasteler, S. D., Cosío, M. G., Sturrock, A., Huecksteadt, T. P., & Hoidal, J. R. (2008) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00318.2007 · Cited by 113
Circulating soluble receptor for advanced glycation end products is inversely associated with body mass index and waist/hip ratio in the general population
Norata, G. D., Garlaschelli, K., Grigore, L., Tibolla, G., Raselli, S., Redaelli, L., Buccianti, G., & Catapano, A. L. (2008) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2008.03.004 · Cited by 105
Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes
Tan, K. C. B., Chow, W.-S., Tso, A. W. K., Xu, A., Tse, H., Hoo, R. L. C., Betteridge, D. J., & Lam, K. S. L. (2007) · Diabetologia · doi:10.1007/s00125-007-0759-0 · Cited by 91
Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12
Wittkowski, H., Hirono, K., Ichida, F., Vogl, T., Ye, F., Yanlin, X., Saito, K., Uese, K., Miyawaki, T., Viemann, D., et al. (2007) · Arthritis & Rheumatism · doi:10.1002/art.23042 · Cited by 77
Advanced Glycation End Product Homeostasis
Vlassara, H., Uribarri, J., Cai, W., & Striker, G. E. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1433.055 · Cited by 76
Angiotensin converting enzyme inhibiting therapy is associated with lower vitreous vascular endothelial growth factor concentrations in patients with proliferative diabetic retinopathy
van Buggenum, I. M. H., Polak, B. C. P., Reichert-Thoen, J. W. M., et al. (2002) · Diabetologia · doi:10.1007/s00125-001-0747-8 · Cited by 76
The triggering of human peritoneal mesothelial cell apoptosis and oncosis by glucose and glycoxydation products
Boulanger, É., Wautier, M.-P., Gane, P., Mariette, C., Devuyst, O., & Wautier, J. (2004) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfh277 · Cited by 76
HIGH LEVELS OF SOLUBLE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS MAY BE A MARKER OF EXTREME LONGEVITY IN HUMANS
Geroldi, D., Falcone, C., Minoretti, P., Emanuele, E., Arra, M., & D’Angelo, A. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00776.x · Cited by 66
Identification of the receptor for advanced glycation end products in synovial tissue of patients with rheumatoid arthritis
Drinda, S., Franke, S., Rüster, M., Petrow, P. K., Pullig, O., Stein, G., & Hein, G. E. (2004) · Rheumatology International · doi:10.1007/s00296-004-0456-y · Cited by 64
Angiotensin II receptor blocker inhibits abnormal accumulation of advanced glycation end products and retinal damage in a rat model of type 2 diabetes
Sugiyama, T., Okuno, T., Fukuhara, M., et al. (2007) · Experimental Eye Research · doi:10.1016/j.exer.2007.06.008 · Cited by 59
Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced glycation endproducts
Nienhuis, H. L. A., de Leeuw, K., Bijzet, J., Smit, A. J., Schalkwijk, C., Graaff, R., Kallenberg, C. G. M., & Bijl, M. (2008) · Rheumatology · doi:10.1093/rheumatology/ken302 · Cited by 56
Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis
Wong, F. S., Dittel, B. N., & Janeway, C. A. (1999) · Immunological Reviews · doi:10.1111/j.1600-065x.1999.tb01309.x · Cited by 46
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-γ2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease
Catalano, M., Cortelazzo, A., Santi, R., Contino, L., Demicheli, M. S. A., Yilmaz, Y. N., Zorzetto, M., Campo, I., Lanati, N., & Emanuele, E. (2008) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2008.05.007 · Cited by 36
AGEs, macrophage colony stimulating factor and vascular adhesion molecule blood levels are increased in patients with diabetic microangiopathy
Wautier, M., Boulanger, É., Guillausseau, P.-J., Massin, P., & Wautier, J. (2004) · Thrombosis and Haemostasis · doi:10.1160/th03-07-0486 · Cited by 36
Decreased levels of soluble receptor for advanced glycation end products in patients with primary Sjögren’s syndrome
Stewart, C., Cha, S., Caudle, R. M., Berg, K. M., & Katz, J. (2008) · Rheumatology International · doi:10.1007/s00296-008-0529-4 · Cited by 31
Receptor of advanced glycation end product (RAGE) expression in the minor salivary glands of patients with Sjo˝gren's syndrome: a preliminary study
Katz, J., Stavropoulos, F., Bhattacharyya, I., Stewart, C., Perez, F., & Caudle, R. M. (2004) · Scandinavian Journal of Rheumatology · doi:10.1080/03009740310004775 · Cited by 25

Flagged first, then by citations

Research works printed but not linked: 1

2008, Nutrition, metabolism, and cardiovascular diseases : NMCD, 19, 129

Sorted by citations

The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction
Sergi, D., Boulestin, H., Campbell, F. M., & Williams, L. M. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900934 · Cited by 194
RAGE Signaling in Skeletal Biology
Plotkin, L. I., Essex, A. L., & Davis, H. M. (2019) · Current Osteoporosis Reports · doi:10.1007/s11914-019-00499-w · Cited by 54

[AGEs and RAGE - advanced glycation end-products and their receptor in questions and answers].
Kalousová, M., & Zima, T. (2014) · PubMed · Cited by 4
Abstract 13855: The Impact of Plasma Levels of Receptor for Advanced Glycation End-products and High Mobility Group Box 1 in Patients With Pulmonary Hypertension
Suzuki, S., Nakazato, K., Sugimoto, K., et al. (2014) · Circulation · doi:10.1161/circ.130.suppl_2.13855
The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines
Chen, R.-C., Yi, P.-P., Zhou, R.-R., Xiao, M.-F., Huang, Z.-B., Tang, D., Huang, Y., & Fan, X. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-1978-6 · Cited by 111
Advanced Glycation End Product Recognition by the Receptor for AGEs
Xue, J., Rai, V., Singer, D. L., Chabierski, S., Xie, J., Reverdatto, S., Burz, D. S., Schmidt, A. M., Hoffmann, R., & Shekhtman, A. G. (2011) · Structure · doi:10.1016/j.str.2011.02.013 · Cited by 218
ADVANCED GLYCATION END PRODUCTS AND THEIR RECEPTORS IN CARDIOVASCULAR DISEASES
Шевцова, А. И., & Ткаченко, В. А. (2019) · Journal of the Grodno State Medical University · doi:10.25298/2221-8785-2019-17-1-11-16 · Cited by 5

Authors: Maillard-Lefebvre, H., Boulanger, E., Daroux, M., Gaxatte, C., Hudson, B. I., & Lambert, M.
Affiliations: Université de Lille (FR)
ORCID: Hudson, B. I.
Lambert, M.
Venue: Rheumatology
Publisher: Oxford University Press (OUP)
Published: 2009-07-09
Volume: 48
Issue: 10
Pages: 1190-1196
ISSN: 1462-0324 (ISSN-L)
1462-0332
DOI: 10.1093/rheumatology/kep199
OpenAlex: W2150894134
Cited by: 190
References: 65
Citations by year: 2026: 4 · 2025: 4 · 2024: 6 · 2023: 7 · 2022: 9 · 2021: 12 · 2020: 10 · 2019: 17 · 2018: 7 · 2017: 9 · 2016: 9 · 2015: 17 · 2014: 18 · 2013: 20 · 2012: 12
FWCI: 1.47
Type: journal article
Language: en
Open access: closed
Locations: Lara D. Veeken (publishedVersion)
PubMed (publishedVersion)
HighWire Press Open Archive (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
Life Sciences › Immunology and Microbiology › Immunology › Biomarkers in Disease Mechanisms
Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
Keywords: soluble receptor for advanced glycation end products, advanced glycation end products, chronic inflammatory diseases, biomarkers, inflammation, atherosclerosis, diabetes mellitus, renal failure, aging, HMGB1, S-100 protein, therapeutic target
MeSH terms: Receptor for Advanced Glycation End Products, Animals, Arthritis, Rheumatoid, Chronic Disease, Humans, Inflammation, Lupus Erythematosus, Systemic, Prognosis, Receptors, Immunologic, Vascular Diseases, Biomarkers, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Soluble receptor for advanced glycation end products: a new biomarker in diagnosis and prognosis of chronic inflammatory diseases

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks