The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
A Selective Review of Recent North American Long-term Followup Studies of Schizophrenia
Open accessAbstract
North American outcome studies of schizophrenia conducted within the past quarter century are reviewed if their minimum average followup is 10 years and they meet at least some modern design criteria. Ten such investigations are described and summarized. Taken as a whole, they demonstrate that schizophrenia can be a chronic disease whose outcome on the average is worse than that of other major mental illnesses. It is associated with an increased risk for suicide, physical illness, and mortality. The schizophrenic process, however, is not relentlessly progressive, as originally described, but appears to plateau after 5-10 years of manifest illness. Overall, outcome is heterogeneous, but much of the variance can be linked to sample characteristics, including expressions of psychopathology (broad vs. narrow diagnostic criteria, subtypes, and comorbidity), dimensions of chronicity (length of manifest illness, treatment resistance, age of onset, and institutionalization), and other predictor variables (gender, marital status, socioeconomic status, physical setting, and premorbid health). Long-term followup studies have yet to demonstrate clearly any effect of treatment on the natural history of schizophrenia. Finally, these studies support a broad definition of schizophrenia.
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Citations
Cites
Diagnostic Criteria for Use in Psychiatric Research
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Cited by
Robinson, D., Woerner, M. G., Alvir, J. M. J., Bilder, R., Goldman, R., Geisler, S., Koreen, A., Sheitman, B., Chakos, M., Mayerhoff, D., et al. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.3.241 · Cited by 1,327
Natural Course of Schizophrenic Disorders: A 15-Year Followup of a Dutch Incidence Cohort
Wiersma, D., Nienhuis, F. J., Slooff, C. J., & Giel, R. (1998) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033315 · Cited by 649
Lieberman, J. A., Perkins, D., Belger, A., Chakos, M., Jarskog, F., Boteva, K., & Gilmore, J. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01303-8 · Cited by 593
Longitudinal study of brain morphology in first episode schizophrenia
Lieberman, J., Chakos, M., Wu, H., Alvir, J., Hoffman, E., Robinson, D., & Bilder, R. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01067-8 · Cited by 554
Recovery in serious mental illness: A new wine or just a new bottle?
Davidson, L., O'Connell, M. J., Tondora, J., Lawless, M., & Evans, A. C. (2005) · Professional Psychology Research and Practice · doi:10.1037/0735-7028.36.5.480 · Cited by 466
Metadata
- Authors
- McGlashan, T. H.
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 1988-01-01
- Volume
- 14
- Issue
- 4
- Pages
- 515-542
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- OpenAlex
- W2127251599
- Cited by
- 554
- References
- 56
- FWCI
- 10.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
