The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Psychopharmacologic Treatment of Schizophrenia
Open accessAbstract
Antipsychotic (neuroleptic) medications continue to be a critical component in the treatment of schizophrenia. Despite numerous advances in brain imaging, genetics, and neurochemistry, the pharmacologic agents routinely used to treat schizophrenia have not changed markedly over the last 30 years. The introduction of clozapine, however, represents an important step in drug development and has stimulated renewed activity in this area. In addition, its novel effects have had a heuristic value in efforts to better understand neuropharmacologic mechanisms. While we await further advances in treatment development, we are benefiting from clinical research focusing on improving our ability to use available pharmacotherapy in the most effective and least toxic manner. Recent studies reemphasize the potential value of using the minimum effective dosage for acute treatment (e.g., 10-15 mg/day of oral haloperidol) and provide needed data on the benefits and risks of long-term dosage reduction strategies (i.e., continuous low-dose or targeted/intermittent treatment).
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Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. (2013) · Encyclopedia of Social Work · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,519
Clozapine for the Treatment-Resistant Schizophrenic: A Double-blind Comparison With Chlorpromazine
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Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs
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Significance of Neuroleptic Dose and Plasma Level in the Pharmacological Treatment of Psychoses
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Cited by
Lehman, A. F., Steinwachs, D. M., & The Co-Investigators of the PORT Project (1998) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033302 · Cited by 910
Mueser, K. T., & McGurk, S. R. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16458-1 · Cited by 876
Research update on the psychosocial treatment of schizophrenia
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.5.607 · Cited by 398
Cognitive therapy for psychosis in schizophrenia: An effect size analysis
Gould, R. A., Mueser, K. T., Bolton, E., Mays, V., & Goff, D. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(00)00145-6 · Cited by 389
The Illness Management and Recovery Program: Rationale, Development, and Preliminary Findings
Mueser, K. T. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbl022 · Cited by 334
Metadata
- Authors
- Kane, J. M., & Marder, S. R.
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 1993-01-01
- Volume
- 19
- Issue
- 2
- Pages
- 287-302
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- OpenAlex
- W2057923287
- Cited by
- 273
- References
- 62
- FWCI
- 12.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
