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Cited by 389Schizophrenia research and treatmentPsychotherapy Techniques and ApplicationsCounseling, Therapy, and Family Dynamics

Cognitive therapy for psychosis in schizophrenia: An effect size analysis

Gould, Robert A., Mueser, Kim T., Bolton, Elisa, Mays, Virgina, Goff, Donald·2001·Schizophrenia Research
DOI 10.1016/s0920-9964(00)00145-6
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Abstract

We conducted a meta-analysis using all available controlled treatment outcome studies of cognitive therapy (CT) for psychotic symptoms in schizophrenia. Effect sizes were calculated for seven studies involving 340 subjects. The mean effect size for reduction of psychotic symptoms was 0.65. The findings suggest that cognitive therapy is an effective treatment for patients with schizophrenia who have persistent psychotic symptoms. Follow-up analyses in four studies indicated that patients receiving CT continued to make gains over time (ES=0.93). Further research is needed to determine the replicability of standardized cognitive interventions, to evaluate the clinical significance of cognitive therapy for schizophrenia, and to determine which patients are most likely to benefit from this intervention.

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  • In five of the seven controlled trials of CT for schizophrenia, there were significant post-treatment differences in psychotic symptoms between control and treatment conditions.

    “Of the seven studies, five reported significant differences in psychotic symptoms between the control and treatment conditions at post-treatment.”

    From The empirical status of cognitive-behavioral therapy: A review of meta-analyses (2006) · cites this paper as Gould et al. (2001)

  • In a meta-analysis of seven controlled trials of CT for schizophrenia, CT produced a large pre-post reduction in psychotic symptoms (grand mean ES=0.65).

    “They found a large effect size for reduction in psychotic symptoms between pre- and post-treatment (grand mean ES=0.65).”

    From The empirical status of cognitive-behavioral therapy: A review of meta-analyses (2006) · cites this paper as Gould et al. (2001)

  • In the four studies providing long-term follow-up, the gains made by patients who received CT were maintained and even increased in magnitude (ES=0.93).

    “Similar to these findings, Gould et al. (2001) reported that in the four studies providing long-term follow-up findings, the gains made by patients who received CT were maintained and even increased in magnitude (ES=0.93).”

    From The empirical status of cognitive-behavioral therapy: A review of meta-analyses (2006) · cites this paper as Gould et al. (2001)

  • In the remaining two of the seven controlled trials of CT for schizophrenia, decreases in psychotic symptoms were non-significant.

    “The remaining two studies found non-significant decreases in psychotic symptoms.”

    From The empirical status of cognitive-behavioral therapy: A review of meta-analyses (2006) · cites this paper as Gould et al. (2001)

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Authors
Gould, R. A., Mueser, K. T., Bolton, E., Mays, V., & Goff, D.
Affiliations
  • Harvard University (US)
  • Dartmouth Psychiatric Research Center (US)
Corresponding author
Gould, Robert A.
ORCID
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2001-03
Volume
48
Issue
2-3
Pages
335-342
ISSN
0920-9964 (ISSN-L)
DOI
10.1016/s0920-9964(00)00145-6
OpenAlex
W2068100666
Cited by
389
References
38
Citations by year
2026: 1 · 2024: 3 · 2023: 6 · 2022: 40 · 2021: 9 · 2020: 6 · 2019: 9 · 2018: 11 · 2017: 9 · 2016: 6 · 2015: 13 · 2014: 13 · 2013: 10 · 2012: 23
FWCI
14.87
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Schizophrenia Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Social Sciences › Psychology › Clinical Psychology › Counseling, Therapy, and Family Dynamics
Keywords
cognitive therapy, schizophrenia
MeSH terms
Cognition Disorders, Female, Follow-Up Studies, Humans, Male, Schizophrenia, Cognitive Behavioral Therapy, Treatment Outcome

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