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Sleep Patterns and Stability in Perimenopausal Women
Abstract
Women between the ages of 40 and 59 years were classified as pre-, peri-, and postmenopausal, with and without hot flash symptoms, for comparison of somnographic sleep variables. Few differences in sleep variables were noted between the groups. However, peri- and postmenopausal women experiencing hot flashes (symptomatic) tended to have lower sleep efficiencies than those not experiencing hot flashes. As well, rapid-eye-movement (REM) latency was longer (p less than 0.05) in the symptomatic women (means = 94.2 min) than in the nonsymptomatic women (means = 71.4 min). Although an age difference existed between the menopausal status groups, it was less than a decade and a main group effect for sleep efficiency and REM latency was seen while controlling for age and/or depression.
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“Although self-reported nocturnal flashes correlate with subjective poor sleep quality, such association is less clear when objective sleep measures are used [96,105,106].”
From Non-Pharmacological Treatment of Insomnia (2012) · cites this paper as [105]
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“However, polysomnographic (PSG) evidence of poorer sleep during this stage is sparse (Shaver et al., 1988; Young et al., 2003; Kalleinen et al., 2008), with a large epidemiological study showing even better PSG sleep in peri- and postmenopausal women, despite less sleep satisfaction, compared with premenopausal women…”
ResultSleep Loss and Fatigue in Healthcare Professionals
Owens, J. A. (2007) · The Journal of Perinatal & Neonatal Nursing · doi:10.1097/01.jpn.0000270624.64584.9d · Cited by 107
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“55 It is possible that the aging processes, as well as conditions such as sleep-disordered breathing, are associated with increased arousals that cause perceptions of disrupted sleep.”
Assessment and treatment of hot flushes and menopausal mood disturbance
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BackgroundFrequency and severity of hot flashes and sleep disturbance in postmenopausal women with hot flashes
Ensrud, K. E., Stone, K. L., Blackwell, T. L., Sawaya, G. F., Tagliaferri, M., Diem, S. J., & Grady, D. (2009) · Menopause · doi:10.1097/gme.0b013e31818c0485 · Cited by 104
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“However, some studies using PSG measures did not observe sleep impairments [12,36], while our study showed significant differences on objective but not on subjective sleep measures.”
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“Menopausal women with hot flashes report more frequent awakenings, reduced sleep efficiency, and poor sleep quality, compared with those without hot flashes (Shaver et al., 1988; Woodward & Freedman, 1994).”
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“17 Among the menopausal groups, there were no clear differences in PSG sleep quality, including PSG sleep fragmentation, arousal, or efficiency.”
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Joffe, H., White, D. P., Crawford, S. L., McCurnin, K. E., Economou, N. I., Connors, S., & Hall, J. E. (2013) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e31828292d1 · Cited by 63
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ResultSex differences in sleep health
Meers, J. M., Stout-Aguilar, J., & Nowakowski, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815373-4.00003-4 · Cited by 69
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Sukwatana, P., Meekhangvan, J., Tamrongterakul, T., et al. (1991) · Maturitas · doi:10.1016/0378-5122(91)90196-w · Cited by 54
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“Subjective complaints of insomnia are common in this population, though consensus has not been reached on alterations in polysomnographic characteristics.(4,5,6,23) The study on which this secondary analysis was based demonstrated a significant improvement in daily hot flashes with the use of gabapentin.”
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BackgroundResultEFFECTS OF LIGHT THERAPY ON SLEEP, MOOD, AND TEMPERATURE IN WOMEN WITH NONSEASONAL MAJOR DEPRESSION
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“6) [30-67] Body mass index, mean (SD) [range], kg/m(2) 25.”
BackgroundInsomnia and sleep apnea in midlife women: prevalence and consequences to health and functioning
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“When hot flashes occur during the night, they frequently but not invariably awaken women from sleep [18,19].”
BackgroundStress, support, psychological states and sleep
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Sleep disturbance in mid‐life women
Clark, A. J., Flowers, J., Boots, L. R., & Shettar, S. M. (1995) · Journal of Advanced Nursing · doi:10.1046/j.1365-2648.1995.22030562.x · Cited by 38
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EVALUATION AND TREATMENT OF CHANGES IN MOOD, SLEEP, AND SEXUAL FUNCTIONING ASSOCIATED WITH MENOPAUSE
Stone, A. B., & Pearlstein, T. B. (1994) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(21)00635-5 · Cited by 36
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“For example, women with nocturnal hot flashes experience greater sleep disruption, as measured by polysomnography (PSG), compared to women who do not experience hot flashes (Shaver et al., 1988; Woodward & Freedman, 1994).”
BackgroundDealing with Menopausal Sleep Disturbances
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Clinical Pharmacology of Sleep
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Body mass index and sleep in women aged 40 to 64 years
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Sleep Disturbance in Midlife Women
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Otte, J. L., Bakoyannis, G., Rand, K. L., Ensrud, K. E., Guthrie, K. A., Joffe, H., McCurry, S. M., Newton, K. M., & Carpenter, J. S. (2019) · Menopause · doi:10.1097/gme.0000000000001343 · Cited by 26
“E xtensive research shows that midlife women report poor sleep during various stages of the menopausal transition and postmenopause.(1-6) For example, at least 48% to 50% of women with hot flashes experience problems with nighttime sleep during late menopause and early postmenopause.”
BackgroundSleep during menopausal transition: a 10-year follow-up
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“The studies evaluating sleep architecture in menopausal transition are sparse and mainly cross sectional, showing few or no changes [6, 7] or suggesting even better sleep after menopause [2, 8].”
BackgroundZak, R., Zitser, J., Jones, H. J., Gilliss, C. L., & Lee, K. A. (2022) · Journal of Women s Health · doi:10.1089/jwh.2021.0328 · Cited by 25
“5 This finding supports the need to consider the influence of BMI on midlife women’s sleep quality in future studies.”
Self-citationSleep and Rest Regulation in Young and Old Oestrogen‐Deficient Female Mice
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Metadata
- Authors
- Shaver, J., Giblin, E., Lentz, M., & Lee, K.
- Affiliations
- University of Washington (US)
- University of California, San Francisco (US)
- Corresponding author
- Shaver, Joan
- Venue
- SLEEP
- Publisher
- Oxford University Press (OUP)
- Published
- 1988-09
- Volume
- 11
- Issue
- 6
- Pages
- 556-561
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W89794934
- Cited by
- 186
- References
- 0
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 2 · 2020: 2 · 2019: 7 · 2018: 3 · 2017: 4 · 2016: 5 · 2015: 6 · 2014: 8 · 2013: 8 · 2012: 6
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- SLEEP (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- sleep patterns, sleep stability, perimenopause, menopause, hot flashes, sleep efficiency, REM latency, middle-aged women, age differences in sleep
- MeSH terms
- Adult, Arousal, Climacteric, Female, Follicle Stimulating Hormone, Humans, Menopause, Middle Aged, Reaction Time, Sleep Stages, Sleep, REM
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