Cited by 112Sleep and related disordersSleep and Wakefulness ResearchSleep and Work-Related Fatigue

A link between short sleep and obesity: building the evidence for causation

Cizza, Giovanni, Skarulis, Monica, Mignot, Emmanuel·2005·SLEEP

Abstract

Dr. Mignot has received research support and speaker honorarium from Cephalon and Orphan Medical; and is a stock holder and advisor of Hypnion, a biotechnology company. Drs. Cizza and Skarulis have indicated no financial conflicts of interest.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/sleep/28.10.1217

Cites

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Insufficient sleep duration (quantity) has been associated with an increased risk of obesity, type 2 diabetes, hypertension, cardiovascular disease, metabolic syndrome, and early mortality.

    “Insufficient sleep duration (quantity) has been associated with an increased risk of obesity (3–6,51), type 2 diabetes (7–11), hypertension (12), cardiovascular disease (13,14), metabolic syndrome (a combination of cardiovascular and metabolic dysfunction) (15), and early mortality (14,16,17,19–21,52).”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

The publisher hasn’t deposited this paper’s reference list.

Research works printed but not linked: 27

  1. Gangwisch JE, Malaspina D, Boden-Albala B, Heymsfield SB. In- adequate sleep as a risk factor for obesity: analysis of the NHANES I. Sleep 2005; 28:1289-1296.
  2. Friedman JM. Modern science versus the stigma of obesity. Nat Med 2004;10:563-9.
  3. Zimmet P, Thomas CR. Genotype, obesity and cardiovascular dis- ease--has technical and social advancement outstripped evolution? J Intern Med. 2003; 254(2):114-25.
  4. Speakman JR. Obesity: the integrated roles of environment and ge- netics. J Nutr 2004;134:2090S-105S.
  5. Kaplan LM. Pharmacological therapies for obesity. Gastroenterol Clin North Am 2005;34:91-104.
  6. Wilding J. Clinical evaluation of anti-obesity drugs. Curr Drug Tar- gets 2004;5:325-32.
  7. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a sys- tematic review and meta-analysis. JAMA 2004;292:1724-37. Erra- tum in: JAMA 2005;293:1728.
  8. Reilly JJ, Armstrong J, Dorosty AR, et al, Avon Longitudinal Study of Parents and Children Study Team. Early life risk factors for obe- sity in childhood: cohort study. BMJ 2005;330:1357.
  9. Vorona RD, Winn MP, Babineau TW, Eng BP, Feldman HR, Ware JC. Overweight and obese patients in a primary care population re- port less sleep than patients with a normal body mass index. Arch Intern Med 2005;165:25-30.
  10. Hasler G, Buysse DJ, Klaghofer R, et al. The association between short sleep duration and obesity in young adults: a 13-year prospec- tive study. Sleep 2004;27:661-6.
  11. Patel SR, Ayas NT, Malhotra MR, et al. A prospective study of sleep duration and mortality risk in women. Sleep 2004;27:440-4.
  12. Cournot M, Ruidavets JB, Marquie JC, Esquirol Y, Baracat B, Fer- rieres J. Environmental factors associated with body mass index in a population of Southern France. Eur J Cardiovasc Prev Rehabil 2004;11:291-7.
  13. Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med 2004;1:e62.
  14. Gupta NK, Mueller WH, Chan W, Meininger JC Is obesity asso- ciated with poor sleep quality in adolescents? Am J Human Biol 2002;14:762-8.
  15. Kripke DF, Garfinkel L, Wingard DL, Klauber MR, Marler MR. Mortality associated with sleep duration and insomnia. Arch Gen Psychiatry 2002;59:131-6.
  16. Sekine M, Yamagami T, Handa K, et al. A dose-response relationship between short sleeping hours and childhood obesity: results of the Toyama Birth Cohort Study. Child Care Health Dev 2002;28:163- 70.
  17. von Kries R, Toschke AM, Wurmser H, Sauerwald T, Koletzko B. Reduced risk for overweight and obesity in 5-and 6-y-old chil- dren by duration of sleep-a cross-sectional study. Int J Obes Relat Metab Disord 2002;26:710-16.
  18. Shigeta H, Shigeta M, Nakazawa A, Nakamura N, Yoshikawa T. Life- style, obesity, and insulin resistance. Diabetes Care 2001;24:608.
  19. Vioque J, Torres A, Quiles J. Time spent watching television, sleep duration and obesity in adults living in Valencia, Spain. Int J Obes Relat Metab Disord 2000;24:1683-8.
  20. Locard E, Mamelle N, Billette A, et al. Risk factors of obesity in a five year old population. Parental versus environmental factors. Int J Obes Relat Metab Disord 1992;16:721-9.
  21. Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on meta- bolic and endocrine function. Lancet 1999;354:1435-9.
  22. Spiegel K, Leproult R, L'hermite-Baleriaux M, Copinschi G, Penev PD, Van Cauter E. Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. J Clin Endocrinol Metab 2004;89:5762- 71.
  23. Spiegel K, Tasali E, Penev P, Van Cauter E. Sleep curtailment in healthy young men is associated with decreased leptin levels, el- evated ghrelin levels, and increased hunger and appetite. Ann Intern Med 2004;141:846-50.
  24. Vgontzas AN, Zoumakis E, Bixler EO, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflamma- tory cytokines. J Clin Endocrinol Metab 2004;89:2119-26.
  25. Mullington JM, Chan JL, Van Dongen HP, et al. Sleep loss reduces diurnal rhythm amplitude of leptin in healthy men. J. Neuroendocri- nol 2003;15:851-4.
  26. Guilleminault C, Powell NB, Martinez S, et al. Preliminary obser- vations on the effects of sleep time in a sleep restriction paradigm. Sleep Med 2003;4:177-84.
  27. Shearer WT, Reuben JM, Mullington JM, et al. Soluble TNF-al- pha receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight. J Allergy Clin Immunol 2001;107:165-70.

Cited by

Sorted by citations

Authors
Cizza, G., Skarulis, M., & Mignot, E.
Affiliations
  • National Institutes of Health (US)
  • Stanford Medicine (US)
Corresponding author
Mignot, Emmanuel
Venue
SLEEP
Published
2005-10
Volume
28
Issue
10
Pages
1217-1220
ISSN
  • 0161-8105 (ISSN-L)
  • 1550-9109
OpenAlex
W137438242
Cited by
111
References
0
Citations by year
2026: 1 · 2024: 2 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 5 · 2017: 5 · 2016: 2 · 2015: 6 · 2014: 9 · 2013: 11 · 2012: 8
FWCI
12.06
Type
journal article
Language
en
Open access
closed
Locations
  • SLEEP (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health
  • National Institute of Mental Health (MH-073435, R01MH073435)
  • National Institute of Diabetes and Digestive and Kidney Diseases
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Keywords
short sleep duration, obesity, causality, sleep deprivation
MeSH terms
Adult, Humans, Life Style, Middle Aged, Obesity, Sleep Deprivation, Body Mass Index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review