The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture
Abstract
The mechanism of action of acupuncture remains largely unknown. The reaction to acupuncture needling known as ‘de qi’, widely viewed as essential to the therapeutic effect of acupuncture, may be a key to understanding its mechanism of action. De qi includes a characteristic needling sensation, perceived by the patient, and ‘needle grasp’ perceived by the acupuncturist. During needle grasp, the acupuncturist feels pulling and increased resistance to further movement of the inserted needle. We hypothesize that 1) needle grasp is due to mechanical coupling between the needle and connective tissue with winding of tissue around the needle during needle rotation and 2) needle manipulation transmits a mechanical signal to connective tissue cells via mechanotransduction. Such a mechanism may explain local and remote, as well as long‐term effects of acupuncture.—Langevin, H. M., Churchill, D. L., Cipolla, M. J. Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture. FASEB J. 15, 2275–2282 (2001)
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Cited by
Evidence of Connective Tissue Involvement in Acupuncture
Langevin, H. M., Churchill, D. L., Wu, J., Badger, G. J., Yandow, J. A., Fox, J. R., & Krag, M. H. (2002) · The FASEB Journal · doi:10.1096/fj.01-0925fje · Cited by 311
Self-citationAcupuncture for Chronic Low Back Pain
Berman, B. M., Langevin, H. M., Witt, C. M., & Dubner, R. (2010) · New England Journal of Medicine · doi:10.1056/nejmct0806114 · Cited by 273
Self-citationCharacterization of the "deqi" response in acupuncture
Hui, K. K., Nixon, E. E., Vangel, M. G., Liu, J., Marina, O., Napadow, V., Hodge, S. M., Rosen, B. R., Makris, N., & Kennedy, D. N. (2007) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-7-33 · Cited by 265
Acupuncture for vascular dementia
Peng, W., Wang, Y., Zhang, Y., & Liang, C. M. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004987.pub2 · Cited by 67
Lu, L.-M., He, J., Zeng, J.-C., Liao, M.-X., Jia, C., & Pan, H.-H. (2017) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-016-2451-z · Cited by 16
Metadata
- Authors
- Langevin, H. M., Churchill, D. L., & Cipolla, M. J.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 2001-10
- Volume
- 15
- Issue
- 12
- Pages
- 2275-2282
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W1972059159
- Cited by
- 477
- References
- 54
- FWCI
- 11.57
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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