Speed kills: cellular and molecular bases of methamphetamine‐induced nerve terminal degeneration and neuronal apoptosis

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Oltval, Z. N., Milliman, C. L., & Korsmeyer, S. J. (1993) · Cell · doi:10.1016/0092-8674(93)90509-o · Cited by 6,003

Death Receptors: Signaling and Modulation

Ashkenazi, A., & Dixit, V. M. (1998) · Science · doi:10.1126/science.281.5381.1305 · Cited by 5,866

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Yang, J., Liu, X., Bhalla, K. N., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., & Wang, X. (1997) · Science · doi:10.1126/science.275.5303.1129 · Cited by 4,913

Caspases: the executioners of apoptosis

Cohen, G. M. (1997) · Biochemical Journal · doi:10.1042/bj3260001 · Cited by 4,737

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Kluck, R. M., Bossy‐Wetzel, E., Green, D. R., & Newmeyer, D. D. (1997) · Science · doi:10.1126/science.275.5303.1132 · Cited by 4,715

Van Damme A.

Haine, M. M.-L., & Meeùs, N. (1986) · Cited by 3,464

Peroxynitrite oxidation of sulfhydryls.

Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,492

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shimizu, S., Narita, M., Tsujimoto, Y., & Tsujimoto, Y. (1999) · Nature · doi:10.1038/20959 · Cited by 2,178

Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

Yang, E., Zha, J., Jockel, J., Boise, L., Thompson, C. B., & Korsmeyer, S. J. (1995) · Cell · doi:10.1016/0092-8674(95)90411-5 · Cited by 2,125

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulumPreprint

Zinszner, H., Kuroda, M., Wang, X., Batchvarova, N., Lightfoot, R. T., Remotti, H. E., Stevens, J. L., & Ron, D. (1998) · Genes & Development · doi:10.1101/gad.12.7.982 · Cited by 2,039

New Insights into the Mechanism of Action of Amphetamines

Fleckenstein, A. E., Volz, T. J., Riddle, E. L., Gibb, J. W., & Hanson, G. R. (2007) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.47.120505.105140 · Cited by 731

Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review

Deepmala, Slattery, J., Kumar, N., Delhey, L., Berk, M., Dean, O., Spielholz, C., & Frye, R. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.015 · Cited by 463

Methamphetamine causes microglial activation in the brains of human abusers

Sekine, Y., Ouchi, Y., Sugihara, G., Takei, N., Yoshikawa, E., Nakamura, K., Iwata, Y., Tsuchiya, K. J., Suda, S., Suzuki, K., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1179-08.2008 · Cited by 381

Neural Activation Patterns of Methamphetamine-Dependent Subjects During Decision Making Predict Relapse

Paulus, M. P., Tapert, S. F., & Schuckit, M. A. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.7.761 · Cited by 369

Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation

Thomas, D. M., Walker, P. D., Benjamins, J. A., Geddes, T. J., & Kuhn, D. M. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.070961 · Cited by 319

Methamphetamine induces neuronal apoptosis via cross‐talks between endoplasmic reticulum and mitochondria‐dependent death cascades

Jayanthi, S., Deng, X., Noailles, P., Ladenheim, B., & Cadet, J. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0295com · Cited by 281

Neurotoxicity of substituted amphetamines: Molecular and cellular mechanisms

Cadet, J. L., Krasnova, I. N., Jayanthi, S., & Lyles, J. (2007) · Neurotoxicity Research · doi:10.1007/bf03033567 · Cited by 271

Drugs and alcohol: Treating and preventing abuse, addiction and their medical consequences

Volkow, N. D., & Li, T. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.06.021 · Cited by 247

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis

Jayanthi, S., Deng, X., Ladenheim, B., McCoy, M. T., Cluster, A. S., Cai, N.-S., & Cadet, J. L. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404990102 · Cited by 223

Neurotoxicity of methamphetamine: Main effects and mechanisms

Jayanthi, S., Daiwile, A. P., & Cadet, J. L. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113795 · Cited by 238

Methamphetamine: Effects on the brain, gut and immune system

Prakash, M. D., Tangalakis, K., Antonipillai, J., Stojanovska, L., Nurgali, K., & Apostolopoulos, V. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.03.009 · Cited by 220

Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity

LaVoie, M. J., Card, J. P., & Hastings, T. G. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.01.010 · Cited by 204

Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines

Thomas, D. M., Dowgiert, J., Geddes, T. J., Francescutti, D. M., Liu, X., & Kuhn, D. M. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.06.065 · Cited by 192

Methamphetamine: History, Pathophysiology, Adverse Health Effects, Current Trends, and Hazards Associated with the Clandestine Manufacture of Methamphetamine

Vearrier, D., Greenberg, M. I., Miller, S. N., Okaneku, J., & Haggerty, D. A. (2012) · Disease-a-Month · doi:10.1016/j.disamonth.2011.09.004 · Cited by 191

Regulation of the dopamine transporter

Schmitt, K. C., & Reith, M. E. A. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05148.x · Cited by 186

Recent Advances in Methamphetamine Neurotoxicity Mechanisms and Its Molecular Pathophysiology

Yu, S., Zhu, L., Shen, Q., Bai, X., & Di, X. (2015) · Behavioural Neurology · doi:10.1155/2015/103969 · Cited by 176

Acute or repeated cocaine administration generates reactive oxygen species and induces antioxidant enzyme activity in dopaminergic rat brain structures

Dietrich, J.-B., Mangeol, A., Revel, M.-O., Burgun, C., Aunis, D., & Zwiller, J. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.01.018 · Cited by 168

Dopaminergic neuron-specific oxidative stress caused by dopamine itself.

Miyazaki, I., & Asanuma, M. (2008) · PubMed · doi:10.18926/amo/30942 · Cited by 168

Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine

Zhang, L., Kitaichi, K., Fujimoto, Y., Nakayama, H., Shimizu, E., Iyo, M., & Hashimoto, K. (2006) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.05.015 · Cited by 159

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148

Involvement of sigma (σ) receptors in the acute actions of methamphetamine: Receptor binding and behavioral studies

Nguyen, E. C., McCracken, K. A., Liu, Y., Pouw, B., & Matsumoto, R. R. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.04.016 · Cited by 146

Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis

Wu, C.-W., Ping, Y., Yen, J., Chang, C., Wang, S., Yeh, C.-L., Chi, C., & Lee, H. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.01.011 · Cited by 143

Effect of antioxidant N-acetyl-l-cysteine on behavioral changes and neurotoxicity in rats after administration of methamphetamine

Fukami, G., Hashimoto, K., Koike, K., Okamura, N., Shimizu, E., & Iyo, M. (2004) · Brain Research · doi:10.1016/j.brainres.2004.04.072 · Cited by 137

Molecular, Behavioral, and Physiological Consequences of Methamphetamine Neurotoxicity: Implications for Treatment

Moszczyńska, A., & Callan, S. P. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.238501 · Cited by 136

MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity

Thomas, D. M., & Kuhn, D. M. (2005) · Brain Research · doi:10.1016/j.brainres.2005.05.049 · Cited by 132

Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine

Cunha‐Oliveira, T., Rego, A. C., Cardoso, S. M., Borges, F., Swerdlow, R. H., Macedo, T., & Oliveira, C. R. (2006) · Brain Research · doi:10.1016/j.brainres.2006.03.061 · Cited by 129

Pharmacotherapy for Methamphetamine Dependence: A Review of the Pathophysiology of Methamphetamine Addiction and the Theoretical Basis and Efficacy of Pharmacotherapeutic Interventions

Rose, M. E., & Grant, J. E. (2008) · Annals of Clinical Psychiatry · doi:10.1080/10401230802177656 · Cited by 121

Varied Access to Intravenous Methamphetamine Self-Administration Differentially Alters Adult Hippocampal Neurogenesis

Mandyam, C. D., Wee, S., Crawford, E. F., Eisch, A. J., Richardson, H. N., & Koob, G. F. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.010 · Cited by 125

Methamphetamine-induced cell death: Selective vulnerability in neuronal subpopulations of the striatum in mice

Zhu, J. P. Q., Xu, W., & Angulo, J. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.02.055 · Cited by 119

Emerging research on methamphetamine

Maxwell, J. C. (2005) · Current Opinion in Psychiatry · doi:10.1097/01.yco.0000165592.52811.84 · Cited by 116

A Coat of Many Colors: Neuroimmune Crosstalk in Human Immunodeficiency Virus Infection

Kraft-Terry, S. D., Buch, S. J., Fox, H. S., & Gendelman, H. E. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.042 · Cited by 115

Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension

Chen, P.-I., Cao, A., Miyagawa, K., Tojais, N. F., Hennigs, J. K., Li, C. G., Sweeney, N. M., Inglis, A. S., Wang, L., Li, D., et al. (2017) · JCI Insight · doi:10.1172/jci.insight.90427 · Cited by 106

Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

Muneer, P. M. A., Alikunju, S., Szlachetka, A. M., Murrin, L. C., & Haorah, J. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-23 · Cited by 104

Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory

Simões, A. P., Silva, A. P., Pereira, F. C., Marques, E., Grade, S., Milhazes, N., Borges, F., Ribeiro, C., & Macedo, T. R. A. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.09.044 · Cited by 104

Methamphetamine Increases Brain Viral Load and Activates Natural Killer Cells in Simian Immunodeficiency Virus-Infected Monkeys

Marcondes, M. C. G., Flynn, C. T., Watry, D. D., Zandonatti, M. A., & Fox, H. S. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090953 · Cited by 98

Involvement of Dopamine Receptors in Binge Methamphetamine-Induced Activation of Endoplasmic Reticulum and Mitochondrial Stress Pathways

Beauvais, G., Atwell, K., Jayanthi, S., Ladenheim, B., & Cadet, J. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028946 · Cited by 98

Oxoguanine Glycosylase 1 Protects Against Methamphetamine-Enhanced Fetal Brain Oxidative DNA Damage and Neurodevelopmental Deficits

Wong, A. W., McCallum, G. P., Jeng, W., & Wells, P. G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2557-08.2008 · Cited by 96

Astrocyte-derived metallothionein protects dopaminergic neurons from dopamine quinone toxicity

Miyazaki, I., Asanuma, M., Kikkawa, Y., Takeshima, M., Murakami, S., Miyoshi, K., Sogawa, N., & Kita, T. (2010) · Glia · doi:10.1002/glia.21112 · Cited by 96

Attenuated microglial activation mediates tolerance to the neurotoxic effects of methamphetamine

Thomas, D. M., & Kuhn, D. M. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02906.x · Cited by 94

Neuropeptide Y Protects against Methamphetamine-Induced Neuronal Apoptosis in the Mouse Striatum

Thiriet, N., Deng, X., Solinas, M., Ladenheim, B., Curtis, W., Goldberg, S. R., Palmiter, R. D., & Cadet, J. L. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4893-04.2005 · Cited by 91

Methamphetamine-induced neurotoxicity: the road to Parkinson’s disease

Thrash, B., Kariharan, T., Ahuja, M., Suppiramaniam, V. D., & Dhanasekaran, M. (2009) · Pharmacological Reports · doi:10.1016/s1734-1140(09)70158-6 · Cited by 88

Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes

Du, S., Qiao, D., Chen, C., Chen, S., Liu, C., Lin, Z., Wang, H., & Xie, W. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00409 · Cited by 82

Melatonin attenuates methamphetamine‐induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK‐N‐SH cells

Kongsuphol, P., Mukda, S., Nopparat, C., Villarroel, A., & Govitrapong, P. (2008) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2008.00648.x · Cited by 81

Long-Term Methamphetamine Administration in the Vervet Monkey Models Aspects of a Human Exposure: Brain Neurotoxicity and Behavioral Profiles

Melega, W. P., Jorgensen, M. J., Laćan, G., Way, B. M., Pham, J., Morton, G. G., Cho, A. K., & Fairbanks, L. A. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301502 · Cited by 78

Genetically correlated effects of selective breeding for high and low methamphetamine consumption

Wheeler, J. M., Reed, C. L., Burkhart‐Kasch, S., Li, N., Cunningham, C. L., Janowsky, A. J., Franken, F. H., Wiren, K. M., Hashimoto, J. G., Scibelli, A. C., et al. (2009) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2009.00522.x · Cited by 77

Methamphetamine Induces Autophagy and Apoptosis in a Mesencephalic Dopaminergic Neuronal Culture Model

Kanthasamy, A., ANANTHARAM, V., ALI, S. F., & KANTHASAMY, A. G. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1369.022 · Cited by 75

Amphetamine induces apoptosis of medium spiny striatal projection neurons via the mitochondria‐dependent pathway

Krasnova, I. N., Ladenheim, B., & Cadet, J. L. (2005) · The FASEB Journal · doi:10.1096/fj.04-2881fje · Cited by 74

Pharmacogenetic Treatments for Drug Addiction: Cocaine, Amphetamine and Methamphetamine

Haile, C. N., Kosten, T. R., & Kosten, T. A. (2009) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990902825447 · Cited by 76

Protein expression profile in the striatum of acute methamphetamine-treated rats

Iwazaki, T., McGregor, I. S., & Matsumoto, I. (2006) · Brain Research · doi:10.1016/j.brainres.2006.04.052 · Cited by 74

Approaches to Prevent Dopamine Quinone-Induced Neurotoxicity

Miyazaki, I., & Asanuma, M. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9843-1 · Cited by 71

Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ

Shin, E., Duong, C. X., Nguyen, X.-K. T., Li, Z., Bing, G., Bach, J. H., Park, D. H., Nakayama, K. I., Ali, S. F., Kanthasamy, A. G., et al. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.04.001 · Cited by 71

Crocin Inhibits Apoptosis and Astrogliosis of Hippocampus Neurons Against Methamphetamine Neurotoxicity via Antioxidant and Anti-inflammatory Mechanisms

Shafahi, M., Vaezi, G., Shajiee, H., Sharafi, S., & Khaksari, M. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2644-2 · Cited by 70

Methamphetamine Administration Causes Death of Dopaminergic Neurons in the Mouse Olfactory Bulb

Deng, X., Ladenheim, B., Jayanthi, S., & Cadet, J. L. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.010 · Cited by 70

Neuropsychological deficits in adolescent methamphetamine abusers

King, G., Alicata, D., Cloak, C. C., & Chang, L. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1949-x · Cited by 70

Protective Effects of N-acetyl-L-cysteine on the Reduction of Dopamine Transporters in the Striatum of Monkeys Treated with Methamphetamine

Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., Shimizu, E., & Iyo, M. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300512 · Cited by 70

Role of nitrergic system in behavioral and neurotoxic effects of amphetamine analogs

Itzhak, Y., & Ali, S. F. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.08.004 · Cited by 67

Effect of methamphetamine self-administration on tyrosine hydroxylase and dopamine transporter levels in mesolimbic and nigrostriatal dopamine pathways of the rat

Shepard, J. D., Chuang, D., Shaham, Y., & Morales, M. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0316-4 · Cited by 66

Effects of Exercise on Depression, Anxiety, Cognitive Control, Craving, Physical Fitness and Quality of Life in Methamphetamine-Dependent Patients

Huang, J., Zheng, Y., Gao, D., Hu, M., & Yuan, T. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00999 · Cited by 65

Protective Effects of Minocycline on the Reduction of Dopamine Transporters in the Striatum After Administration of Methamphetamine: A Positron Emission Tomography Study in Conscious Monkeys

Hashimoto, K., Tsukada, H., Nishiyama, S., Fukumoto, D., Kakiuchi, T., & Iyo, M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.019 · Cited by 65

Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: Relevance to oxidative damage in Parkinson's disease

Anantharam, V., Lehrmann, E., Kanthasamy, A., Yang, Y., Banerjee, P., Becker, K. G., Freed, W. J., & Kanthasamy, A. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.02.003 · Cited by 65

Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion

Gillingwater, T. H. (2006) · Brain · doi:10.1093/brain/awl101 · Cited by 67

Attenuation of Cocaine and Methamphetamine Neurotoxicity by Coenzyme Q10

Klongpanichapak, S., Govitrapong, P., SHARMA, S. K., & Ebadi, M. (2006) · Neurochemical Research · doi:10.1007/s11064-005-9025-3 · Cited by 65

Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamine

Cai, D., Huang, E., Luo, B., Yang, Y., ZHANG, F., Liu, C., Lin, Z., Xie, W.-B., & Wang, H. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.67 · Cited by 62

SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation

Robson, M. J., Turner, R. C., Naser, Z. J., McCurdy, C. R., Huber, J. D., & Matsumoto, R. R. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.04.009 · Cited by 60

The Scourge of Methamphetamine: Impact on a Level I Trauma Center

Swanson, S. M., Sise, C. B., Sise, M. J., Sack, D. I., Holbrook, T. L., & Paci, G. M. (2007) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e318074d3ac · Cited by 61

Alteration of blood-brain barrier function by methamphetamine and cocaine

Dietrich, J. B. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0777-y · Cited by 61

The role of endogenous serotonin in methamphetamine‐induced neurotoxicity to dopamine nerve endings of the striatum

Thomas, D. M., Angoa‐Pérez, M., Francescutti, D. M., Shah, M. M., & Kuhn, D. M. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06950.x · Cited by 59

Interactions of HIV and methamphetamine: Cellular and molecular mechanisms of toxicity potentiation

Cadet, J. L., & Krasnova, I. N. (2007) · Neurotoxicity Research · doi:10.1007/bf03033915 · Cited by 59

Neurotoxicology of Synthetic Cathinone Analogs

Angoa‐Pérez, M., Anneken, J. H., & Kuhn, D. M. (2016) · Current topics in behavioral neurosciences · doi:10.1007/7854_2016_21 · Cited by 60

Neurotoxic Effects of Methamphetamine

Thrash, B., Karuppagounder, S. S., Uthayathas, S., Suppiramaniam, V. D., & Dhanasekaran, M. (2009) · Neurochemical Research · doi:10.1007/s11064-009-0042-5 · Cited by 59

Persistence of tolerance to methamphetamine-induced monoamine deficits

Danaceau, J. P., Deering‐Rice, C. E., Day, J. E., Smeal, S. J., Johnson‐Davis, K. L., Fleckenstein, A. E., & Wilkins, D. G. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.11.045 · Cited by 59

Methamphetamine and MDMA (Ecstasy) Neurotoxicity: 'of Mice and Men'

Itzhak, Y., & Achat‐Mendes, C. (2004) · IUBMB Life · doi:10.1080/15216540410001727699 · Cited by 59

Immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users

Kitamura, O., Tokunaga, I., Gotohda, T., & Kubo, S. (2006) · International Journal of Legal Medicine · doi:10.1007/s00414-006-0087-9 · Cited by 59

Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway

Sharikova, A. V., Quaye, E., Park, J. Y., Maloney, M. C., Desta, H., Thiyagarajan, R., Seldeen, K. L., Parikh, N. U., Sandhu, P., Khmaladze, A. T., et al. (2018) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-018-9787-4 · Cited by 59

Binge Use and Sex and Drug Use Behaviors among HIV(–), Heterosexual Methamphetamine Users in San Diego

Cheng, W. S., Garfein, R. S., Semple, S. J., Strathdee, S. A., Zians, J. K., & Patterson, T. L. (2009) · Substance Use & Misuse · doi:10.3109/10826080902869620 · Cited by 58

Turn on fluorescence sensing of vapor phase electron donating amines via tetraphenylporphyrin or metallophenylporphrin doped polyfluorene

He, C., He, Q., Deng, C., Shi, L., Zhu, D., Fu, Y., Cao, H., & Cheng, J. (2010) · Chemical Communications · doi:10.1039/c0cc01972k · Cited by 58

Differential neurochemical consequences of an escalating dose‐binge regimen followed by single‐day multiple‐dose methamphetamine challenges

Graham, D. L., Noailles, P.-A. H., & Cadet, J. L. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05269.x · Cited by 58

Methamphetamine Preconditioning Alters Midbrain Transcriptional Responses to Methamphetamine-Induced Injury in the Rat Striatum

Cadet, J. L., McCoy, M. T., Cai, N. S., Krasnova, I. N., Ladenheim, B., Beauvais, G., Wilson, N., Wood, W. H., Becker, K. G., & Hodges, A. B. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007812 · Cited by 58

Cyclooxygenase-2 Is an Obligatory Factor in Methamphetamine-Induced Neurotoxicity

Thomas, D. M., & Kuhn, D. M. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.080242 · Cited by 58

Proteomic profiling of proteins associated with methamphetamine-induced neurotoxicity in different regions of rat brain

Li, X., Wang, H., Qiu, P., & Luo, H. L. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.06.014 · Cited by 57

Methamphetamine administration impairs behavior, memory and underlying signaling pathways in the hippocampus

Golsorkhdan, S. A., Boroujeni, M. E., Aliaghaei, A., Abdollahifar, M., Ramezanpour, A., Nejatbakhsh, R., Anarkooli, I. J., Barfi, E., & Fridoni, M. J. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112300 · Cited by 55

Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats

He, J., Xu, H., Yang, Y., Zhang, X., & Li, X. (2004) · Brain Research · doi:10.1016/j.brainres.2004.05.060 · Cited by 54

MDMA, methamphetamine and their combination: possible lessons for party drug users from recent preclinical research

Clemens, K. J., McGregor, I. S., Hunt, G. E., & Cornish, J. L. (2007) · Drug and Alcohol Review · doi:10.1080/09595230601036945 · Cited by 55

L-Ascorbate Protects Against Methamphetamine-Induced Neurotoxicity of Cortical Cells via Inhibiting Oxidative Stress, Autophagy, and Apoptosis

Huang, Y.-N., Yang, L.-Y., Wang, J.-Y., Lai, C.-C., Chiu, C.-T., & Wang, J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9561-z · Cited by 57

Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain

Kaewsuk, S., Sae‐ung, K., Phansuwan‐Pujito, P., & Govitrapong, P. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.04.010 · Cited by 53

Do Preclinical Findings of Methamphetamine-Induced Motor Abnormalities Translate to an Observable Clinical Phenotype?

Caligiuri, M. P., & Buitenhuys, C. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300859 · Cited by 52

Methamphetamine and its impact on dental care.

Klasser, G. D., & Epstein, J. B. (2005) · PubMed · Cited by 52

Caspase-11 Plays an Essential Role in Methamphetamine-Induced Dopaminergic Neuron Apoptosis

Huang, W., Xie, W., Qiao, D., Qiu, P., Huang, E., Li, B., Chen, C., Liu, C., Wang, Q., Lin, Z., et al. (2015) · Toxicological Sciences · doi:10.1093/toxsci/kfv014 · Cited by 51

Methamphetamine Causes Alterations in the MAP Kinase-Related Pathways in the Brains of Mice that Display Increased Aggressiveness

Sokolov, B. P., & Cadet, J. L. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300891 · Cited by 51

The Crosstalk Between Neurons and Glia in Methamphetamine-Induced Neuroinflammation

Shi, S., Chen, T., & Zhao, M. (2022) · Neurochemical Research · doi:10.1007/s11064-021-03513-9 · Cited by 53

Modeling Human Methamphetamine Exposure in Nonhuman Primates: Chronic Dosing in the Rhesus Macaque Leads to Behavioral and Physiological Abnormalities

Madden, L. J., Flynn, C. T., Zandonatti, M. A., May, M., Parsons, L. H., Katner, S. N., Henriksen, S. J., & Fox, H. S. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300575 · Cited by 50

Effect of N-acetylcysteine and/or deferoxamine on oxidative stress and hyperactivity in an animal model of mania

Valvassori, S. S., Petronilho, F. C., Réus, G. Z., Steckert, A. V., Oliveira, V. B. M., Boeck, C. R., Kapczinski, F. P., Dal‐Pizzol, F., & Quevedo, J. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.02.012 · Cited by 49

Psychiatric Symptoms and HPA Axis Function in Adolescent Methamphetamine Users

King, G., Alicata, D., Cloak, C. C., & Chang, L. (2010) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-010-9206-y · Cited by 49

Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine

Chen, H., Wu, J., Zhang, J., Fujita, Y., Ishima, T., Iyo, M., & Hashimoto, K. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2619-3 · Cited by 49

A validated gas chromatographic–electron impact ionization mass spectrometric method for methylenedioxymethamphetamine (MDMA), methamphetamine and metabolites in oral fluid

Scheidweiler, K. B., & Huestis, M. A. (2006) · Journal of Chromatography B · doi:10.1016/j.jchromb.2006.03.020 · Cited by 48

Serotonin neurotoxins — past and present

Baumgarten, H. G., & Lachenmayer, L. (2004) · Neurotoxicity Research · doi:10.1007/bf03033455 · Cited by 49

Role of Sigma Receptors in Methamphetamine-Induced Neurotoxicity

Kaushal, N., & Matsumoto, R. R. (2011) · Current Neuropharmacology · doi:10.2174/157015911795016930 · Cited by 48

A functional glutathioneS‐transferase P1 gene polymorphism is associated with methamphetamine‐induced psychosis in Japanese population

Hashimoto, T., Hashimoto, K., Matsuzawa, D., Shimizu, E., Sekine, Y., Inada, T., Ozaki, N., Iwata, N., Harano, M., Komiyama, T., et al. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30164 · Cited by 47

Environmental Enrichment does not Reduce the Rewarding and Neurotoxic Effects of Methamphetamine

Thiriet, N., Gennequin, B., Lardeux, V., Chauvet, C., Decressac, M., Janet, T., Jaber, M., & Solinas, M. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9158-2 · Cited by 51

Methamphetamine induces macropinocytosis in differentiated SH-SY5Y human neuroblastoma cells

Nara, A., Aki, T., Funakoshi, T., & Uemura, K. (2010) · Brain Research · doi:10.1016/j.brainres.2010.07.043 · Cited by 46

Involvement of multiple molecular events in methamphetamine‐induced neurodegeneration: evidence from cDNA array analysis

Cadet, J. L. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00011.x

Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review

Cadet, J. L., Jayanthi, S., & Deng, X. (2005) · Neurotoxicity Research · doi:10.1007/bf03033973 · Cited by 134

Methamphetamine induces neuronal apoptosis via cross‐talks between endoplasmic reticulum and mitochondria‐dependent death cascades

Jayanthi, S., Deng, X., Noailles, P., Ladenheim, B., & Cadet, J. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0295com · Cited by 281

Molecular Mechanisms of Methamphetamine-Induced Neurotoxicity: Insights Obtained Through cDNA Array Analyses

Jayanthi, S., McCoy, M. T., & Cadet, J. L. (2007) · Springer eBooks · doi:10.1007/978-0-387-30377-2_10

Methamphetamine toxicity and messengers of death

Krasnova, I. N., & Cadet, J. L. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.03.002 · Cited by 598