The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.
Mitochondrial spare respiratory capacity: Mechanisms, regulation, and significance in non‐transformed and cancer cells
Abstract
Mitochondrial metabolism must constantly adapt to stress conditions in order to maintain bioenergetic levels related to cellular functions. This absence of proper adaptation can be seen in a wide array of conditions, including cancer. Metabolic adaptation calls on mitochondrial function and draws on the mitochondrial reserve to meet increasing needs. Among mitochondrial respiratory parameters, the spare respiratory capacity (SRC) represents a particularly robust functional parameter to evaluate mitochondrial reserve. We provide an overview of potential SRC mechanisms and regulation with a focus on its particular significance in cancer cells.
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Cites
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Cited by
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice
Al-Habsi, M., Chamoto, K., Matsumoto, K., Nomura, N., Zhang, B., Sugiura, Y., Sonomura, K., Maharani, A., Nakajima, Y., Wu, Y., et al. (2022) · Science · doi:10.1126/science.abj3510 · Cited by 223
Metadata
- Authors
- Marchetti, P., Fovez, Q., Germain, N., Khamari, R., & Kluza, J.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 2020-08-17
- Volume
- 34
- Issue
- 10
- Pages
- 13106-13124
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W3071840836
- Cited by
- 322
- References
- 128
- FWCI
- 10.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Marchetti, P., Fovez, Q., Germain, N., Khamari, R., & Kluza, J. (2020). Mitochondrial spare respiratory capacity: Mechanisms, regulation, and significance in non‐transformed and cancer cells. The FASEB Journal. https://doi.org/10.1096/fj.202000767r
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
